Biomedical Nanomaterials, Stoika

Advances In Polymeric Nanomaterials For Biomedical Applications examines advanced polymer synthetic strategies for developing novel biomaterials for use in medicine. With a strong focus on fundamentals and structure, the authors also explore their fabrication, as well as current and potential biomedical applications.

The book begins with a look at the fundamentals of polymeric nanomaterials and their properties. The text goes on to discuss the design of biomaterials and their applications in drug delivery. Further chapters explore other important applications such as imaging and regenerative medicine, including current challenges and future trends.

This valuable resource is especially useful for materials and polymer scientists, and bioengineers wishing to broaden their knowledge of polymeric nanobiomaterials.

• Covers the complete spectrum of polymer nanomaterials used in biomedical applications
• Includes various applications such as drug delivery, gene delivery, bio-imaging, tissue engineering and regenerative medicine, anti-microbial agents and neuroscience together for the first time in this area
• Explores fundamental correlations between structures, properties and applications as well as synthetic strategies for polymer nanomaterials

In the early chapters, the book discusses the overall progress of novel nanomaterial applications in the biomedical, environmental and energy fields, introducing the synthesis, characterization, properties and applications of novel nanomaterials, in a practical fashion. The book goes on to discuss biomedical applications, and the electrocatalytical and photothermal effects of novel nanomaterials for efficient energy applications, before summarizing the latest progress in application development.

The book is invaluable to academic researchers and biomedical clinicians working with nanomaterials.

• Offers comprehensive characterization details of novel and emerging nanomaterials which will help in their vast applications
• Presents a comprehensive view of emerging ways to synthesize more efficient nanomaterials
• Describes and monitors the functions of applications of new and emerging nanomaterials in the biomedical, environmental and energy fields, which is very useful in the development of new and more efficient materials

This timely resource for scientists and engineers in this rapidly advancing field features contributions from over 30 leaders who address advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials, along with expert opinions on a range of 2D nanomaterials that have therapeutic and diagnostic applications.

• Presents advanced methods and strategies for controlling the physical-chemical properties of 2D nanomaterials
• Provides state-of-the-art biomedical applications for 2D nanomaterials, including graphene and boron nitride
• Includes key information from a broad selection of subject areas for researchers in both materials, engineering and medicine

• Provides a valuable resource of recent scientific progress, highlighting the most well-known applications of nanostructures in drug delivery systems
• Includes novel opportunities and ideas for developing or improving technologies in composites by companies, biomedical industries, and in related sectors
• Features at least 50% of references from the last 2-3 years

This collection brings together novel methodologies and strategies adopted in the research and development of bioengineered nanomaterials and technology. Renowned international researchers discuss topics including:

• Nanoemulsions as a vaccine adjuvant
• Bioceramic nanomaterials in medical applications
• Natural and synthetic nanoporous membranes for cell encapsulation therapy
• Inorganic nanoparticle materials for the controlled release of drugs
• Nanomedicine in brain tumor treatment
• Nanoparticles for the treatment of solid tumors and metastasis
• Near-infrared-resonant gold nanoshells and carbon nanotubes in tumor imaging
• Toxicity testing and bioapplications of silver nanoparticles
• Innovative approaches to improve bioactive properties and molecular signaling in cells to stimulate bone repair

The book is written for readers from diverse backgrounds across chemistry, physics, materials science and engineering, medical science, pharmacy, biotechnology, and biomedical engineering. It offers a comprehensive view of cutting-edge research on nanomaterials of biotechnological importance.

The reader also gets a tutorial introduction to the computer software used to generate 3D illustrations that are used throughout the book. The first authors are early-career researchers from the Australian Nanotechnology Network.

Abstract of Dissertation............................................................................................................ i

Table of Contents.................................................................................................................... iv

List of Figures and Tables....................................................................................................... vi

Chapter 1. Introduction of Graphene-based Nanomaterials

1.1. Applications in Biology and Medical Science.................................................................. 1

1.1.1. Sensing Applications...................................................................................................... 2

1.1.2. Therapeutic Applications............................................................................................... 3

1.1.3. Fluorescence Bio-imaging............................................................................................. 4

1.2.1. Enhancing the Stability under Physiological Conditions.............................................. 7

1.2.2. Reduction of GOs........................................................................................................... 8

1.3.1. In vitro Toxicity of Graphene-based Nanomaterials..................................................... 9

1.3.2. In vivo Toxicity of Graphene-based Nanomaterials.................................................... 11

1.4. Perspectives and Other Applications.............................................................................. 15

1.5. References....................................................................................................................... 17

Chapter 2. Catalytic Degradation of Phenols by Recyclable CVD Grapehene Films

1.1. Abstract............................................................................................................................ 21

1.2. Introduction..................................................................................................................... 22

1.4. Conclusion....................................................................................................................... 31

1.5. Experimental................................................................................................................... 32

1.7. References....................................................................................................................... 37

Chapter 3. Graphene Quantum Dots Prevent α-synucleinopathy in Parkinson's Disease

1.2. Results and Discussion.................................................................................................... 40

1.3. Conclusion....................................................................................................................... 54