Автор: Christian W. Kreipke; Jose A. Rafols Название: Cerebral Blood Flow, Metabolism, and Head Trauma ISBN: 1493901508 ISBN-13(EAN): 9781493901500 Издательство: Springer Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reflecting the most recent advances in our understanding of TBI pathotrajectory, this guide is aimed at a broad range of clinicians. It suggests avenues for future research and focuses on issues such as the role of cerebral blood flow in brain trauma recovery.
Автор: M. Segal; Berislav V. Zlokovic Название: The Blood-Brain Barrier, Amino Acids and Peptides ISBN: 0746201222 ISBN-13(EAN): 9780746201220 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain.
Автор: David Kobiler; Shlomo Lustig; Shlomo Shapira Название: Blood-Brain Barrier ISBN: 1461351413 ISBN-13(EAN): 9781461351412 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the 44th OHOLO Conference on Blood-Brain Barrier: Drug Delivery and Brain Pathology, held September 10-14, 2000, Dead Sea, Israel
Автор: Howard M. Eisenberg Название: The Cerebral Microvasculature ISBN: 1468437542 ISBN-13(EAN): 9781468437546 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Symposium takes as its focus of interest the micro- vasculature of the brain and includes considerations of blood flow, the properties of vessel walls and the control of flow and permeability.
Автор: Dorovini-Zis, Katerina Название: The Blood-Brain Barrier in Health and Disease, Volume One ISBN: 0367738120 ISBN-13(EAN): 9780367738129 Издательство: Taylor&Francis Рейтинг: Цена: 48990.00 T Наличие на складе: Нет в наличии.
Автор: Dorovini-Zis, Katerina Название: The Blood-Brain Barrier in Health and Disease, Volume Two ISBN: 0367737698 ISBN-13(EAN): 9780367737696 Издательство: Taylor&Francis Рейтинг: Цена: 48990.00 T Наличие на складе: Нет в наличии.
Автор: Cader Название: Physiology, Pharmacology and Pathology of the Blood-Brain Barrier ISBN: 3030996530 ISBN-13(EAN): 9783030996536 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: This book presents a comprehensive collection of current knowledge and leading research about the blood-brain barrier. The chapters are organized in four main parts providing basic information and novel insights about the physiology of the blood-brain barrier, the challenges related to finding and developing drugs crossing the blood-brain barrier, experimental methods to study the blood-brain barrier and the role of the blood-brain barrier in disease mechanisms and its consequences for drug development. In the first part the readers will discover the structure, function and developmental aspects of the blood-brain barrier and gain novel insights into the complexity and functionality of the neurovascular unit and energy metabolism of brain endothelial cells. Chapters of the second part focus on translational challenges from the bench to the bedside in CNS drug development, shed light on the importance to understand the brain distribution of drugs related to their efficacy, elaborate on general pharmacokinetic considerations for CNS drugs and introduce current and novel drug delivery strategies to overcome the blood-brain barrier. The experimental part of the book covers mathematical and in vitro models as well as animal and human methods in blood-brain barrier research. Specific emphasis is set on the description of the methods, the role of species differences for data interpretation, novel human models based on stem cells with the potential for personalized medicine and technical considerations and tips helpful for readers interested in working with these models. In the fourth part particular attentions is given to the blood-brain barrier, its changes and participation during disease progression. Chapters summarize alterations of the blood-brain barrier that are present in common disorders such as Alzheimer’s disease, multiple sclerosis, stroke, traumatic brain injury, epilepsy and brain tumors. Present therapies will be discussed and the consequences for novel treatment approaches that need to bypass the blood-brain-barrier will be explored. In addition, experts discuss the question in how far changes at the blood-brain barrier are causally linked to disease progressions and consequently could serve as therapeutic targets. This collection is designed to appeal to a wide readership from students through basic and applied scientist to pharmacologists, medical doctors and stakeholders from the pharmaceutical industry and regulatory affairs. Due its comprehensive content the book has the potential to become a standard work in the field of blood-brain barrier research.
Автор: Stone Название: The Blood-Brain Barrier ISBN: 1071622919 ISBN-13(EAN): 9781071622919 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume features techniques to explore the complex interface that separates the systemic circulation from the central nervous system, known as the blood-brain barrier (BBB). Beginning with an introduction to its physiology, the book continues with sections on using pluripotent stem cells in models of the BBB, co-culture, permeability and transwell models, microfluidic and chip models, as well as models to study specific BBB pathologies. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, The Blood-Brain Barrier: Methods and Protocols collects a wide range of methodologies which will aid all researchers in the fascinating world of the blood-brain barrier.
Автор: Bradbury, Michael Название: The Blood-Brain Barrier and Drug Delivery to the CNS ISBN: 0824703944 ISBN-13(EAN): 9780824703943 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Blood-brain barrier ISBN: 1493989456 ISBN-13(EAN): 9781493989454 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This volume focuses on experimental research with applicable models to study physiology, biochemistry, and molecular biology of the blood-brain barrier (BBB). This book is organized into six parts: Part One is an overview of the physiology of BBB; Part Two explores in vitro cell models to study the BBB; Part Three discusses techniques in vivo and ex vivo models to evaluate BBB in Drosophila melanogaster, Zebrafish, and rodents; Part Four looks at permeability, influx, efflux transportation, and drug delivery through the BBB; Part Five talks about various invasive and non-invasive imaging techniques to study BBB; and Part Six describes how molecular biomarkers are used to look at the integrity or dysfunction of the BBB. In Neuromethods series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory.
Cutting-edge and thorough, Blood-Brain Barrier is a valuable resource to aid both novice and experienced investigators with performing experiments using new and classic translational approaches.
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
