Autoimmunity versus Carcinogenesis in Tissue Injury, Lawrence M. Agius
Автор: Tollefsbol, Trygve Название: The Epigenetics of Autoimmunity ISBN: 0128099127 ISBN-13(EAN): 9780128099124 Издательство: Elsevier Science Рейтинг: Цена: 159450.00 T Наличие на складе: Нет в наличии. Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.
Автор: A. Pullman; Paul O.P. Ts`O; H. Gelboin Название: Carcinogenesis: Fundamental Mechanisms and Environmental Effects ISBN: 9027711712 ISBN-13(EAN): 9789027711717 Издательство: Springer Рейтинг: Цена: 278580.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the 13th Jerusalem Symposium on Quantum Chemistry and Biochemistry held in Jerusalem, Israel, April 28-May 2, 1980
Автор: Harri U. Vainio; Eino K. Hietanen Название: Mechanisms in Carcinogenesis and Cancer Prevention ISBN: 3642078591 ISBN-13(EAN): 9783642078590 Издательство: Springer Рейтинг: Цена: 330870.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume describes the present state of the art in carcinogenesis, possibilities for cancer prevention, and gives genetic background in cancer development. Attention is given to the host-environment interaction, considering how this interaction may lead to cancer formation and how it can be utilised in cancer prevention.
Автор: Kendric Smith Название: Aging, Carcinogenesis, and Radiation Biology ISBN: 1475716648 ISBN-13(EAN): 9781475716641 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A summary of data on natural adducts to DNA thus serves to introduce the subject of the radiation and chemical enhancement of DNA adduct formation.
Автор: George G. Skouteris Название: Liver Carcinogenesis ISBN: 3642792170 ISBN-13(EAN): 9783642792175 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the NATO Advanced Study Institute on Molecular Aspects of Liver Carcinogenesis, held at City of Delphi, Greece, January 8 - 18, 1994
Автор: Stavridis Название: Oxidation: The Cornerstone of Carcinogenesis ISBN: 1402067038 ISBN-13(EAN): 9781402067037 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is unique due to its collective approach to the key aspects of the interdependency between three entities: oxidative stress, tobacco smoke and carcinogenesis, operating in a cause-effect sequence, in a concise and to the point manner.
Автор: Xianglin Shi; Vince Castranova; Val Vallyathan; Wi Название: Molecular Mechanisms of Metal Toxicity and Carcinogenesis ISBN: 1461352428 ISBN-13(EAN): 9781461352426 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: During the last two decades, chemical and cellular studies have contributed enormously to our understanding of metal-induced carcinogenesis, and many hypotheses on the role of metals in pathophysiological processes have been investigated. In addition, new techniques are available to shed light on the mechanism of carcinogenesis in molecular terms. This conference on Molecular Mechanisms of Metal Toxicity and Carcinogenesis in September 2000 focused on the latest research in molecular mechanisms of metal-induced toxicity and carcinogenesis. The conference promoted a multidisciplinary investigative approach and included presentations from international experts on state-of-the-art information in this field.
Автор: Jonathan J. Li; Satyabrata Nandi; Sara A. Li Название: Hormonal Carcinogenesis ISBN: 1461392101 ISBN-13(EAN): 9781461392101 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Additionally, gonadotrophins playa role in the etiology of ovarian and testicular cancers and thyroid-stimulating hormones in thyroid cancers.
Автор: C.F. Arlett; Colin S. Cooper; Philip L. Grover; D. Название: Chemical Carcinogenesis and Mutagenesis II ISBN: 3642747809 ISBN-13(EAN): 9783642747809 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: I have been privileged to witness and participate in the great growth of knowledge on chemical carcinogenesis and mutagenesis since 1939 when I entered graduate school in biochemistry at the University of Wisconsin- Madison.
Автор: Clayson, David B. Название: Toxicological Carcinogenesis ISBN: 0367273276 ISBN-13(EAN): 9780367273279 Издательство: Taylor&Francis Рейтинг: Цена: 153120.00 T Наличие на складе: Нет в наличии. Описание: First published in 2001, written by an expert with more than fifty years experience, Toxicological Carcinogenesis provides a summary of current information available on chemicals that induce cancer and an appendix containing bibliographic references, making the text easy to use as a reference.
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