Cluster randomised trials, Hayes, Richard J. (london School Of Hygiene & Tropical Medicine, Uk) Moulton, Lawrence H. (johns Hopkins Bloomberg School Of Public Health, Baltimore,
Автор: Abonyi JГЎnos, Feil BalГЎzs Название: Cluster Analysis for Data Mining and System Identification ISBN: 3764379871 ISBN-13(EAN): 9783764379872 Издательство: Springer Рейтинг: Цена: 93130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents new approaches to data mining and system identification. Algorithmsthat can be used for the clustering of data have been overviewed. New techniques andtools are presented for the clustering, classification, regression and visualization ofcomplex datasets. Special attention is given to the analysis of historical process data,tailored algorithms are presented for the data driven modeling of dynamical systems,determining the model order of nonlinear input-output black box models, and thesegmentation of multivariate time-series. The main methods and techniques areillustrated through several simulated and real-world applications from data mining andprocess engineering practice.The books is aimed primarily at practitioners, researches, and professionals in statistics,data mining, business intelligence, and systems engineering, but it is also accessible tograduate and undergraduate students in applied mathematics, computer science, electricaland process engineering. Familiarity with the basics of system identification and fuzzysystems is helpful but not required.
Автор: Miyamoto Sadaaki Название: Theory of Agglomerative Hierarchical Clustering ISBN: 9811904197 ISBN-13(EAN): 9789811904196 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book discusses recent theoretical developments in agglomerative hierarchical clustering. A fundamental theorem for single linkage using a fuzzy graph is proved, which uncovers several theoretical features of single linkage.
Автор: Campbell Название: How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research ISBN: 1119992028 ISBN-13(EAN): 9781119992028 Издательство: Wiley Рейтинг: Цена: 70700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A much-needed guide to the design and analysis of cluster randomized trials, How to Design, Analyse and Report Cluster Randomised Trials in Medicine and Health Related Research delivers practical guidance on the design and analysis of cluster randomised trials (cRCTs) in healthcare research.
Автор: Hayes Название: Cluster Randomised Trials, Second Edition ISBN: 1498728227 ISBN-13(EAN): 9781498728225 Издательство: Taylor&Francis Рейтинг: Цена: 132710.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Cluster Randomised Trials, Second Edition explores the advantages of cluster randomisation, with special attention given to evaluating the effects of interventions against infectious diseases. Avoiding unnecessary mathematical detail, it covers basic concepts underlying the use of cluster randomisation.
Автор: Sandra Eldridge,Sally Kerry Название: A Practical Guide to Cluster Randomised Trials in Health Services Research ISBN: 0470510471 ISBN-13(EAN): 9780470510476 Издательство: Wiley Рейтинг: Цена: 67530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book addresses the statistical, practical, and ethical issues arising from allocating groups of individuals, or clusters, to different interventions.
Автор: Atkinson, Anthony C , Biswas, Atanu Название: Randomised Response-Adaptive Designs in Clinical Trials ISBN: 0367378973 ISBN-13(EAN): 9780367378974 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Randomised Response-Adaptive Designs in Clinical Trials presents methods for the randomised allocation of treatments to patients in sequential clinical trials. Emphasizing the practical application of clinical trial designs, the book is designed for medical and applied statisticians, clinicians, and statisticians in training.
After introducing clinical trials in drug development, the authors assess a simple adaptive design for binary responses without covariates. They discuss randomisation and covariate balance in normally distributed responses and cover many important response-adaptive designs for binary responses. The book then develops response-adaptive designs for continuous and longitudinal responses, optimum designs with covariates, and response-adaptive designs with covariates. It also covers response-adaptive designs that are derived by optimising an objective function subject to constraints on the variance of estimated parametric functions. The concluding chapter explores future directions in the development of adaptive designs.
Автор: Christopher J. Bulpitt Название: Randomised Controlled Clinical Trials ISBN: 1475763603 ISBN-13(EAN): 9781475763607 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Bradford Hill has defined a clinical trial as "A carefully and ethically designed experiment with the aim of answering some precisely framed question" [1].
Randomised Clinical Trials: Design, Practice and Reporting provides a detailed overview of the methodology for conducting clinical trials, including developing protocols, data capture, randomisation, analysis and reporting. Assuming no prior background, this user-friendly resource describes the statistical, regulatory, and practical components required for conducting randomised clinical trials. Numerous examples and case studies from industry, academia, and the research literature help readers understand each stage of the clinical trial process.
This second edition contains extensively revised material throughout, including new chapters covering designs for repeated measures, non-inferiority, cluster and stepped wedge trials. Other new chapters describe data and safety monitoring, biomarker studies, and feasibility studies. Updated and expanded sections discuss situations where multiple organs, different body locations or competing risks are involved, subgroup analysis, and multiple outcomes. Written by an author team with extensive experience in conducting clinical trials, this book:
Provides comprehensive coverage of randomised clinical trials, ranging from basic to advanced
Features several new chapters, updated case studies and examples, and references to changes in regulations
Explains basic randomised trials, including the parallel two-group controlled trial with a single outcome measure
Covers paired trial designs and trials with more than two interventions
Includes a chapter on miscellaneous topics such as adaptive designs, large simple trials, Bayesian methods for very small trials, alpha-spending functions and the predictive probability test
Randomised Clinical Trials is essential reading for clinicians, nurses, data managers, and medical statisticians involved in clinical trials, and for health practitioners responsible for direct patient care in a clinical trial setting.
Автор: Allan Donner, Neil Klar Название: Design and Analysis of Cluster Randomization Trials in Health Research ISBN: 0470711000 ISBN-13(EAN): 9780470711002 Издательство: Wiley Рейтинг: Цена: 67530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A cluster randomization trial is one in which intact social units, or clusters of individuals, are randomized to different intervention groups.
Название: Spatial Cluster Modelling ISBN: 0367454912 ISBN-13(EAN): 9780367454913 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Невозможна поставка. Описание:
Research has generated a number of advances in methods for spatial cluster modelling in recent years, particularly in the area of Bayesian cluster modelling. Along with these advances has come an explosion of interest in the potential applications of this work, especially in epidemiology and genome research.
In one integrated volume, this book reviews the state-of-the-art in spatial clustering and spatial cluster modelling, bringing together research and applications previously scattered throughout the literature. It begins with an overview of the field, then presents a series of chapters that illuminate the nature and purpose of cluster modelling within different application areas, including astrophysics, epidemiology, ecology, and imaging. The focus then shifts to methods, with discussions on point and object process modelling, perfect sampling of cluster processes, partitioning in space and space-time, spatial and spatio-temporal process modelling, nonparametric methods for clustering, and spatio-temporal cluster modelling. Many figures, some in full color, complement the text, and a single section of references cited makes it easy to locate source material. Leading specialists in the field of cluster modelling authored each chapter, and an introduction by the editors to each chapter provides a cohesion not typically found in contributed works. Spatial Cluster Modelling thus offers a singular opportunity to explore this exciting new field, understand its techniques, and apply them in your own research.
Accurate sample size calculation ensures that clinical studies have adequate power to detect clinically meaningful effects. This results in the efficient use of resources and avoids exposing a disproportionate number of patients to experimental treatments caused by an overpowered study.
Sample Size Calculations for Clustered and Longitudinal Outcomes in Clinical Research explains how to determine sample size for studies with correlated outcomes, which are widely implemented in medical, epidemiological, and behavioral studies.
The book focuses on issues specific to the two types of correlated outcomes: longitudinal and clustered. For clustered studies, the authors provide sample size formulas that accommodate variable cluster sizes and within-cluster correlation. For longitudinal studies, they present sample size formulas to account for within-subject correlation among repeated measurements and various missing data patterns. For multiple levels of clustering, the level at which to perform randomization actually becomes a design parameter. The authors show how this can greatly impact trial administration, analysis, and sample size requirement.
Addressing the overarching theme of sample size determination for correlated outcomes, this book provides a useful resource for biostatisticians, clinical investigators, epidemiologists, and social scientists whose research involves trials with correlated outcomes. Each chapter is self-contained so readers can explore topics relevant to their research projects without having to refer to other chapters.
Автор: Chaoqun Ma, Guojun Gan, Jianhong Wu Название: Data Clustering: Theory, Algorithms, and Applications ISBN: 1611976324 ISBN-13(EAN): 9781611976328 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 81090.00 T Наличие на складе: Нет в наличии. Описание: Data clustering, also known as cluster analysis, is an unsupervised process that divides a set of objects into homogeneous groups. Since the publication of the first edition of this monograph in 2007, development in the area has exploded, especially in clustering algorithms for big data and open-source software for cluster analysis. This second edition reflects these new developments.Data Clustering: Theory, Algorithms, and Applications, Second Edition:covers the basics of data clustering,includes a list of popular clustering algorithms, andprovides program code that helps users implement clustering algorithms.
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