This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Gregory Gregoriadis; Brenda McCormack Название: Targeting of Drugs 5 ISBN: 0306455048 ISBN-13(EAN): 9780306455049 Издательство: Springer Рейтинг: Цена: 74490.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of a NATO ASI held in Cape Sounion, Greece, June 24-July 5, 1995
Polysaccharide-Based Nanocomposites for Gene Delivery and Tissue Engineering presents quantitative background on new polysaccharide nanocomposites in a clear and logical way, highlighting the most exciting applications in gene delivery and tissue engineering and their progress. The book focuses on the different types of polysaccharide nanocomposites for gene delivery and tissue engineering and covers polysaccharide hydrogels for tissue engineering and polysaccharide magnetic nanocomposites for gene delivery. Chapters cover various nanocomposites presented in twenty-one separate chapters. This book will be of great interest to all those researching the development and applications of polysaccharide-based nanocomposites for modeling.
As polysaccharide-based nanocomposites promise cutting-edge applications in gene delivery and tissue engineering, with their development at the forefront of modern medicine, this book is a welcome title on this exciting science.
Presents quantitative background on new polysaccharide nanocomposites for advanced medicine
Focuses on polysaccharide nanocomposites in relation to gene delivery and tissue engineering
Highlights the most exciting, leading-edge applications in gene delivery and tissue engineering
Covers polysaccharide hydrogels for tissue engineering and magnetic nanocomposites for gene delivery
Offers a logical and useful presentation of polysaccharide nanocomposites organized first by application and then by nanocomposite
Автор: Yiyun Cheng Название: Polymeric Gene Delivery Systems ISBN: 3030085597 ISBN-13(EAN): 9783030085599 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: ?The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
The chapter 'Polymeric Nanoparticle-Mediated Gene Delivery for Lung Cancer Treatment' is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Название: Biotechnology in the modern medicinal system ISBN: 1771889721 ISBN-13(EAN): 9781771889728 Издательство: Taylor&Francis Рейтинг: Цена: 133730.00 T Наличие на складе: Нет в наличии. Описание: Presents an informative picture of the state-of-the-art research and development of actionable knowledge in medical biotechnology, specifically involving gene therapy, immunotherapy, and targeted drug delivery systems.
Автор: Ronit Satchi-Fainaro; Ruth Duncan Название: Polymer Therapeutics II ISBN: 3642067190 ISBN-13(EAN): 9783642067198 Издательство: Springer Рейтинг: Цена: 269260.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Floyd, Kory (University of Arizona, USA) Schrodt, Paul Erbert, Larry A. (University Colorado Denver, USA) Scharp, Kristina M. (University of Washington, USA) Название: Gene Delivery ISBN: 1032025549 ISBN-13(EAN): 9781032025544 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Gene therapy involves altering the genes in the body`s cells in an effort to treat or stop disease, instead of using drugs or surgery. This book discusses the development of gene therapy today, from the technology involved to gene correction and the advances in genome editing.
Автор: Donglu Shi Название: Bio-Inspired Nanomaterials and Applications: Nano Detection, Drug/Gene Delivery, Medical Diagnosis and Therapy ISBN: 9814616915 ISBN-13(EAN): 9789814616911 Издательство: World Scientific Publishing Рейтинг: Цена: 95040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book intends to provide an up-to-date information in the field of nanobiomedicine. The focus of the book is on the basic concepts and recent developments in the field of nanotechnology.
Автор: Aaron S. Goldstein Название: Biomaterials For Cell Delivery ISBN: 1498743161 ISBN-13(EAN): 9781498743167 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Нет в наличии. Описание: The purpose of this book is to summarize key strategies and recent accomplishments in the area of developing cell/biomaterial constructs for regenerative medicine. The bulk of the book is devoted to unique problems associated with key tissue and organ targets.
Автор: Anil Kumar Bajpai, Rajesh Saini, Abhilasha Mishra, Jaya Kumar Bajpai, Atul Tiwari Название: Stimuli-Responsive Drug Delivery Systems: From Introduction to Application ISBN: 1501518836 ISBN-13(EAN): 9781501518836 Издательство: Walter de Gruyter Цена: 96630.00 T Наличие на складе: Нет в наличии. Описание:
Stimuli responsive drug delivery systems have emerged as one of the most innovative classes of polymer materials of modern materials science. The book offers a convincing approach to understanding the basic principles of drug delivery process, their mathematical modeling, different types of drug delivery systems, various polymer systems responsive to stimuli such as swelling, pH, temperature, light, chemical agents, electric and magnetic fields.
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