Автор: Cornel Mulhardt Название: Molecular Biology and Genomics, ISBN: 0120885468 ISBN-13(EAN): 9780120885466 Издательство: Elsevier Science Рейтинг: Цена: 45150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.
Автор: Brauer Fred Название: Mathematical models in population biology and epidemiology ISBN: 1489993983 ISBN-13(EAN): 9781489993984 Издательство: Springer Рейтинг: Цена: 42390.00 T Наличие на складе: Есть Описание: This book balances theory and application in the use of mathemathical models for addressing questions in epidemiology and population studies. This latest revised edition makes extensive use of both examples and exercise problems throughout the text.
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 80630.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Автор: Robert F. Costantino; Robert A. Desharnais Название: Population Dynamics and the Tribolium Model: Genetics and Demography ISBN: 1461278236 ISBN-13(EAN): 9781461278238 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The study of populations is becoming increasingly focused on dynamics. We believe there are two reasons for this trend. The ftrst is the impactof nonlinear dynamics with its exciting ideas and colorful language: bifurcations, domains of attraction, chaos, fractals, strange attractors. Complexity, which is so very much a part of biology, now seems to be also a part of mathematics. A second trend is the accessibility of the new concepts. Thebarriers tocommunicationbetween theoristandexperimentalistseemless impenetrable. The active participationofthe experimentalist means that the theory will obtain substance. Our role is the application of the theory of dynamics to the analysis ofbiological populations. We began our work early in 1979 by writing an ordinary differential equation for the rateofchange in adult numbers which was based on an equilibrium model proposed adecadeearlier. Duringthenextfewmonths weftlledournotebookswithstraightforward deductions from the model and its associated biological implications. Slowly, some of the biological observations were explained and papers followed on a variety of topics: genetic and demographic stability, stationary probability distributions for population size, population growth asabirth-deathprocess, natural selectionanddensity-dependent population growth, genetic disequilibrium, and the stationary stochastic dynamics of adult numbers.
Автор: Martin F. Polz; Om P. Rajora Название: Population Genomics: Microorganisms ISBN: 3030047555 ISBN-13(EAN): 9783030047559 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Population genomics is a rapidly emerging field that has the potential to transform our understanding of how evolutionary forces shape genomic diversity among microbes. There have already been considerable advances in understanding gene flow and spread of adaptive traits, and in linking epidemiology with evolutionary biology. The current challenge is to find unifying evolutionary principles for organisms that display a wide range of reproductive biology – from highly clonal to promiscuous – and for which the vast majority have eluded cultivation. This requires interdisciplinary approaches that incorporate novel computational tools, testing of existing and novel population genetic models, and creative new ways of linking genetic diversity to ecological factors. This pioneering book will discuss the advances made and promises of population genomics in microorganisms, outlining some of the key theoretical and practical challenges for microbial population genomics, including defining and identifying populations, genomics-based reverse ecology and building appropriate tools to understand microbes in a variety of complex environments.
Автор: Hartl, Daniel L. (higgins Professor Of Biology, Higgins Professor Of Biology, Department Of Immunology And Infectious Diseases, Harvard University, Us Название: Primer of population genetics and genomics ISBN: 019886230X ISBN-13(EAN): 9780198862307 Издательство: Oxford Academ Рейтинг: Цена: 50680.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
Автор: Paradis, Emmanuel Название: Population Genomics with R ISBN: 1138608181 ISBN-13(EAN): 9781138608184 Издательство: Taylor&Francis Рейтинг: Цена: 132710.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a reference on modern statistical and data exploration methods for the population genomics. It covers a wide range of methods within the R computing environment. The readers will be assumed to have basic knowledge in population genetics, computational methods, and statistics, although some basic principles will be explained.
Автор: Julien Y. Dutheil Название: Statistical Population Genomics ISBN: 1071602012 ISBN-13(EAN): 9781071602010 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques.
Автор: Julien Y. Dutheil Название: Statistical Population Genomics ISBN: 1071601989 ISBN-13(EAN): 9781071601983 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This open access volume presents state-of-the-art inference methods in population genomics, focusing on data analysis based on rigorous statistical techniques.
Автор: Lohmueller Kirk E., Nielsen Rasmus Название: Human Population Genomics: Introduction to Essential Concepts and Applications ISBN: 3030616444 ISBN-13(EAN): 9783030616441 Издательство: Springer Цена: 89750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Section 1: Population genetic theory 1. Coalescent models (all the basics) (John Wakeley: wakeley@fas.harvard.edu) 2. Linkage disequilibrium (Monty Slatkin: slatkin@berkeley.edu) a. r 2, D' b. LD and population history c. Recombination and LD 3. Analysis of population structure (Per Sjцdin, Lucie Gattepaille, Pontus Skoglund, Carina Schlebusch, and Mattias Jakobsson): mattias.jakobsson@ebc.uu.se) d. How do we quantify population structure? e. PCA f. Estimating Trees g. Likelihood based genealogical approaches h. FST i. Estimation of parameters based on SFS j. STRUCTURE analyses k. Admixture HMMs l. D statistics? 4. Inferring selection from population genetic DNA sequence data (David Enard) m. Frequency spectrum-based approaches . Haplotype-based approaches o. Multi-population-based approaches Section 2: Association studies and medical genetics 5. Methods for association studies (John Witte and Rebecca Graff) a. Case-control studies b. Family based studies c. Quantitative traits d. Controlling for stratification . Multiple testing, etc. 6. IBD Mapping for complex traits (Elizabeth Thompson: eathomp@u.washington.edu) 7. What have we learned from GWAS? (Ben Voight: bvoight@broadinstitute.org) p. Effect sizes q. Missing heritability Section 3: Human evolutionary population genetics 8. Human origins and ancient human demographic history (Jeff Wall: WallJ@humgen.ucsf.edu) 9. Evidence and examples of selective sweeps across the human genome (Leslie S. Emery and Josh Akey: akeyj@uw.edu)
Автор: Hartl Daniel L. Название: A Primer of Population Genetics and Genomics ISBN: 0198862296 ISBN-13(EAN): 9780198862291 Издательство: Oxford Academ Рейтинг: Цена: 182010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This accessible primer has been completely revised and updated to provide a concise but comprehensive introduction to the basic concepts of population genetics and genomics.
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