Complex Trait Prediction: Methods and Protocols, Ahmadi Nourollah, Bartholomй Jйrфme
Автор: Kwok Pui-Yan Название: Single Nucleotide Polymorphisms / Methods and Protocols ISBN: 0896039684 ISBN-13(EAN): 9780896039681 Издательство: Springer Цена: 55400.00 T Наличие на складе: Есть Описание: Pui-Yan Kwok, MD, PhD, has assembled a comprehensive collection of readily reproducible techniques for the difficult process of single nucleotide polymorphisms (SNP) discovery and genotyping. These cutting-edge protocols for mutation/SNP detection utilize denaturing high-performance liquid chromatography (dHPLC), single-strand conformation polymorphism (SSCP), conformation-sensitive gel electrophoresis (CSGE), chemical cleavage, and direct sequencing. Equally powerful and up-to-date methods are given for genotyping SNPs, including molecular beacons, the Taqman assay, single-base extension approaches, pyrosequencing, ligation, the Invader assay, and primer extension with mass spectrometry detection.
Автор: Didenko Vladimir V. Название: In Situ Detection of DNA Damage / Methods and Protocols ISBN: 0896039528 ISBN-13(EAN): 9780896039520 Издательство: Springer Рейтинг: Цена: 38730.00 T Наличие на складе: Есть Описание: In In Situ Detection of DNA Damage: Methods and Protocols, Vladimir Didenko and a panel of experts describe all the major in situ techniques for studying DNA damage and apoptosis, and how approaches originally designed to label apoptotic cells can be used for DNA damage analysis (and vice versa). The readily reproducible techniques presented here include all those designed to detect specific single- and double-stranded DNA breaks in tissue sections while using polymerases, ligases, nucleases, and kinases. There are also novel instrumental techniques that use ultrasound for in vivo and in situ detection of apoptotic DNA damage, and in situ applications of flow and laser-scanning cytometry for analysis of DNA strand breaks and apoptosis. State-of-the-art and highly practical, In Situ Detection of DNA Damage: Methods and Protocols presents for the first time a complete set of enzymatic methods for determining DNA breaks, and will greatly facilitate the work of all those studying the in situ detection of DNA damage and the labeling of apoptotic cells.
Автор: Zachariou Michael Название: Affinity Chromatography / Methods and Protocols ISBN: 1588296598 ISBN-13(EAN): 9781588296597 Издательство: Springer Рейтинг: Цена: 13330.00 T Наличие на складе: Есть Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.
Автор: Kihara Daisuke Название: Protein Function Prediction: Methods and Protocols ISBN: 1493983687 ISBN-13(EAN): 9781493983681 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Preface... Table of Contents... Contributing Authors... 1. Using PFP and ESG Protein Function Prediction Web Servers Qing Wei, Joshua McGraw, Ishita Khan, and Daisuke Kihara 2. GHOSTX: A Fast Sequence Homology Search Tool for Functional Annotation of Metagenomic Data Shuji Suzuki, Takashi Ishida, Masahito Ohue, Masanori Kakuta, and Yutaka Akiyama 3. From Gene Annotation to Function Prediction for Metagenomics Fatemeh Sharifi and Yuzhen Ye 4. An Agile Functional Analysis of Metagenomic Data using SUPER-FOCUS Genivaldo Gueiros Z. Silva, Fabyano A. C. Lopes, and Robert A. Edwards 5. MPFit: Computational Tool for Predicting Moonlighting Proteins Ishita Khan, Joshua McGraw, and Daisuke Kihara 6. Predicting Secretory Proteins with SignalP Henrik Nielsen 7. The ProFunc Function Prediction Server Roman A. Laskowski 8. G-LoSA for Prediction of Protein-Ligand Binding Sites and Structures Hui Sun Lee andWonpil Im 9. Local Alignment of Ligand Binding Sites in Proteins for Polypharmacology and Drug Repositioning Michal Brylinski 10. WATsite2.0 with PyMOL Plugin: Hydration Site Prediction and Visualization Ying Yang, Bingjie Hu, and Markus A. Lill 11. Enzyme Annotation and Metabolic Reconstruction Using KEGG Minoru Kanehisa 12. Ortholog Identification and Comparative Analysis of Microbial Genomes using MBGD and RECOG Ikuo Uchiyama 13. Exploring Protein Function Using the Saccharomyces Genome Database Edith D. Wong 14. Network-Based Gene Function Prediction in Mouse and Other Model Vertebrates using MouseNet Server Eiru Kim and Insuk Lee 15. The FANTOM5 Computation Ecosystem: Genomic Information Hub for Promoters and Active Enhancers Imad Abugessaisa, Shuhei Noguchi, Piero Carninci, and Takeya Kasukawa 16. Multi-Algorithm Particle Simulations with Spatiocyte Satya N. V. Arjunan and Koichi Takahashi
Автор: Goldberg Martin W. Название: The Nuclear Pore Complex: Methods and Protocols ISBN: 1071623362 ISBN-13(EAN): 9781071623367 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume covers all methods used to discover the composition, structure, and dynamics of the nuclear pore complex (NPC), as well as the soluble transport factors involved in the transport process.
Автор: Wendy A. Harwood Название: Barley: Methods and Protocols ISBN: 1493989421 ISBN-13(EAN): 9781493989423 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This detailed volume explores barley as both a crop and a model, with practical techniques such as crossing barley, a range of tissue culture methods, the preparation of barley tissues for different forms of microscopy, and the assessment of sensitivity to abiotic stresses. Efficient protocols are provided for transformation, TILLING, virus-induced gene silencing and genome editing. There is also particular emphasis on a range of protocols for genotyping and for the analysis of gene expression. Written for the highly successful Methods in Molecular Biology series, chapters include introductions on their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and easy-to-use, Barley: Methods and Protocols serves as a valuable reference volume for cereal researchers and breeders by providing detailed protocols covering important traditional skills such as crossing and tissue culture through to the latest technologies for genotyping, expression analysis, and genome editing.
Название: Methods and applications of crystal structure prediction ISBN: 1788011708 ISBN-13(EAN): 9781788011709 Издательство: Royal Society of Chemistry Рейтинг: Цена: 179520.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume gathers key researchers representing the full scientific scope of the crystal structure prediction.
Автор: Ying Xu; Dong Xu; Jie Liang Название: Computational Methods for Protein Structure Prediction and Modeling ISBN: 1441922067 ISBN-13(EAN): 9781441922069 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Volume Two of this two-volume sequence presents a comprehensive overview of protein structure prediction methods and includes protein threading, De novo methods, applications to membrane proteins and protein complexes, structure-based drug design, as well as structure prediction as a systems problem.
Автор: Raza Khalid Название: Computational Intelligence Methods in Covid-19: Surveillance, Prevention, Prediction and Diagnosis ISBN: 9811585334 ISBN-13(EAN): 9789811585333 Издательство: Springer Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: 1. An Introduction to Computational Intelligence in COVID-19: Surveillance, Prevention, Prediction, and Diagnosis.- 2. Role of Computational Intelligence against COVID-19.- 3. Using Computational Intelligence for Tracking COVID-19 Outbreak in Online Social Networks.- 4. Social Network Analysis for the Identification of Key Spreaders during COVID-19.- 5. Mobile Technology Solution for COVID -19: Surveillance and Prevention.- 6. The Role of Internet of Things (IoT) in the Containment and Spread of the Novel COVID-19 Pandemic.- 7. A Review on Predictive Systems and Data Models for COVID-19.- 8. A Comparative Study of the SIR Prediction Models and Disease Control Strategies: A Case Study of the State of Kerala, India.- 9. Computational Intelligence Approach for Prediction of COVID-19 using Particle Swarm Optimization. 10. COVID-19 Insightful Data Visualization and Forecasting using Elasticsearch.
Автор: Harald Kirchsteiger; John Bagterp J?rgensen; Eric Название: Prediction Methods for Blood Glucose Concentration ISBN: 3319259113 ISBN-13(EAN): 9783319259116 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book tackles the problem of overshoot and undershoot in blood glucose levels caused by delay in the effects of carbohydrate consumption and insulin administration. The ideas presented here will be very important in maintaining the welfare of insulin-dependent diabetics and avoiding the damaging effects of unpredicted swings in blood glucose – accurate prediction enables the implementation of counter-measures. The glucose prediction algorithms described are also a key and critical ingredient of automated insulin delivery systems, the so-called “artificial pancreas”. The authors address the topic of blood-glucose prediction from medical, scientific and technological points of view. Simulation studies are utilized for complementary analysis but the primary focus of this book is on real applications, using clinical data from diabetic subjects. The text details the current state of the art by surveying prediction algorithms, and then moves beyond it with the most recent advances in data-based modeling of glucose metabolism. The topic of performance evaluation is discussed and the relationship of clinical and technological needs and goals examined with regard to their implications for medical devices employing prediction algorithms. Practical and theoretical questions associated with such devices and their solutions are highlighted. This book shows researchers interested in biomedical device technology and control researchers working with predictive algorithms how incorporation of predictive algorithms into the next generation of portable glucose measurement can make treatment of diabetes safer and more efficient.
Автор: Raza Khalid Название: Computational Intelligence Methods in COVID-19: Surveillance, Prevention, Prediction and Diagnosis ISBN: 9811585369 ISBN-13(EAN): 9789811585364 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: 1. An Introduction to Computational Intelligence in COVID-19: Surveillance, Prevention, Prediction, and Diagnosis.- 2. Role of Computational Intelligence against COVID-19.- 3. Using Computational Intelligence for Tracking COVID-19 Outbreak in Online Social Networks.- 4. Social Network Analysis for the Identification of Key Spreaders during COVID-19.- 5. Mobile Technology Solution for COVID -19: Surveillance and Prevention.- 6. The Role of Internet of Things (IoT) in the Containment and Spread of the Novel COVID-19 Pandemic.- 7. A Review on Predictive Systems and Data Models for COVID-19.- 8. A Comparative Study of the SIR Prediction Models and Disease Control Strategies: A Case Study of the State of Kerala, India.- 9. Computational Intelligence Approach for Prediction of COVID-19 using Particle Swarm Optimization. 10. COVID-19 Insightful Data Visualization and Forecasting using Elasticsearch.
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