Автор: Peiman Hematti; Armand Keating Название: Mesenchymal Stromal Cells ISBN: 1493941291 ISBN-13(EAN): 9781493941292 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this book, leading authorities actively involved in this field provide state-of-the-art knowledge of the basic biology, translational requirements and latest clinical experience with Mesenchymal Stromal Cell (MSC) biology.
Автор: Peiman, Hematti Название: Mesenchymal Stromal Cells ISBN: 0128028262 ISBN-13(EAN): 9780128028261 Издательство: Elsevier Science Рейтинг: Цена: 97690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.
Автор: Reichrath Jцrg, Reichrath Sandra Название: Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling ISBN: 3030364240 ISBN-13(EAN): 9783030364243 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer.
Автор: Reichrath Jцrg, Reichrath Sandra Название: Notch Signaling in Embryology and Cancer: Molecular Biology of Notch Signaling ISBN: 3030364216 ISBN-13(EAN): 9783030364212 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer.
1. Notch signalling and embryology: an introduction
2. Notch signaling and embryonic development: an ancient friend, revisited
3. The Five Faces of Notch Signalling During Drosophila melanogaster Embryonic CNS Development
4. Epigenetic regulation of Notch signaling during Drosophila development
5. Regulation of proneural wave propagation through a combination of Notch-mediated lateral inhibition and EGF-mediated reaction diffusion
6. A nucleolar protein, Nepro, is essential for the maintenance of early neural stem cells and preimplantation embryos
7. The role of Notch signaling in leg development in Drosophila melanogaster
8. Notch pathway and inherited diseases: challenge and promise
Index
Автор: Kakoli Bose; Pradip Chaudhari Название: Unravelling Cancer Signaling Pathways: A Multidisciplinary Approach ISBN: 9813298154 ISBN-13(EAN): 9789813298156 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Нет в наличии. Описание: Unravelling the intricate cell signalling networks and their significance in cancer poses major intellectual challenge. Keeping this in mind, the book aims at understanding the mechanism of action of different proteins and their complexes in the cancer signalling pathways. Hence, the proposed book that comprises 20 chapters provides a comprehensive introduction on cell signalling, its alterations in cancer, molecules that have been popular targets as well as the ones that are emerging as targets. In addition, it discusses different forms of therapy that are coming up for its treatment. Other than that, a major portion of the book is focused on studying different disciplines at the interface of biology and other areas of science that are being used to understand cancer biology in depth.
Название: Cancer Cell Signaling ISBN: 1771880678 ISBN-13(EAN): 9781771880671 Издательство: Taylor&Francis Рейтинг: Цена: 137810.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This title includes a number of Open Access chapters.
Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an overview of the field and how various cell biology techniques are used to better understand cancer on a cellular level. This easily accessible reference volume offers a comprehensive look at the field of cancer cell signaling. Edited by a researcher from Florida Atlantic University, Cancer Cell Signaling: Targeting Signaling Pathways Towards Therapeutic Approaches to Canceris an authoritative and easy-to-use reference.
Автор: Jian-Ying Wang Название: Polyamine Cell Signaling ISBN: 1617376795 ISBN-13(EAN): 9781617376795 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Polyamines are organic cations found in all eukaryotic cells and intimately involved in, and required for, distinct biological functions. An increasing body of evidence indicates that the regulation of cellular polyamines is a central convergence point for the multiple signaling pathways driving various cellular functions. Over the last decade, considerable progress has been made in und- standing the molecular functions of cellular polyamines. These significant findings provide a fundamental basis to not only define the exact role of polyamines in physiology, but also to develop new therapeutic approaches for cancers and other diseases. The major objective of this book is to provide a timely and long lasting guide for investigators in the fields of polyamines, physiology, pharmacology, and cancer research. It will provide a foundation based on research and address the potential for subsequent applications in clinical practice. Polyamine Cell Signaling: Physiology, Pharmacology, and Cancer Research is divided into four main parts: Part I: Polyamines in Signal Transduction of Cell Proliferation Part II: Polyamines in Cellular Signaling of Apoptosis, Carcinogenesis, and Cancer Therapy Part III: Polyamines in Cell Motility and Cell-Cell Interactions Part IV: Polyamine Homeostasis and Transport This book not only covers the current state-of-the-art findings relevant to cellular and molecular functions of polyamines, but also provides the underlying conceptual basis and knowledge regarding potential therapeutic targeting of polyamines and polyamine metabolism. These points are addressed by int- nationally recognized experts in their contributions to this book.
Автор: Mariana Garcia Название: Mesenchymal Stromal Cells as Tumor Stromal Modulators ISBN: 0128031026 ISBN-13(EAN): 9780128031025 Издательство: Elsevier Science Рейтинг: Цена: 124640.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Mesenchymal stromal/ stem cells (MSCs) represent a heterogeneous cell population with immunomodulating, tissue repairing, differentiating, migratory and angiogenic abilities, making them important tools for clinical and translational research. An understanding of the role of MSCs in modulating tumor growth provides a glimpse into their role in non-pathological tissue remodeling and potential regenerative tissue therapies. Mesenchymal Stromal Cells as Tumor Stromal Modulators is a comprehensive source for the understanding of the role of MSCs as ubiquitous connective tissue cell components, which may have both direct and indirect effects on the tumor microenvironment and potential for regenerative therapeutics for various diseases. Using cancer as a model disease, this book explores the transformative role MSCs play in the recruitment of disease cells, cell repair and immunological defenses.
Автор: Owens Название: Stromal Immunology ISBN: 3319781251 ISBN-13(EAN): 9783319781259 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years.
Автор: Weimbs, Thomas Название: Methods In Kidney Cell Biology Part B,154 ISBN: 0128203358 ISBN-13(EAN): 9780128203354 Издательство: Elsevier Science Рейтинг: Цена: 156080.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Methods in Kidney Cell Biology, Part B, Volume 154 represents state-of-the-art techniques in renal research that are ideal for veterans, graduate students, postdoctoral fellows, clinical scientists and principal investigators. Topics in the new release include Single glomerular proteomics - a novel method in translational glomerular cell biology, Measurement of cytosolic and intraciliary calcium in live cells, Differentiation of human kidney organoids from pluripotent stem cells, Quantifying autophagic flux in kidney tissue using structured illumination microscopy, the Generation of primary cells from ADPKD and normal human kidneys, ADPKD cell proliferation and Cl-dependent fluid secretion, In vitro cyst formation of ADPKD cells, and much more.
