Автор: Michael S. Goligorsky Название: Regenerative Nephrology, ISBN: 0123809282 ISBN-13(EAN): 9780123809285 Издательство: Elsevier Science Цена: 108080 T Наличие на складе: Невозможна поставка. Описание:
Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts.
* Presents a comprehensive, translational source for all aspects of renal stem cells, tissue regeneration, and stem cell therapies for renal diseases in one reference work. This will ultimately result in time savings for academic, medical and pharma researchers.
* Experts in the renal stem cell system in kidney repair and regeneration take readers from the bench research to new therapeutic approaches, providing a common language for nephrology researchers, fellows and other stem cell researchers. This enables the discussion of development of stem cells and their use in the repair and regeneration of the kidney.
Автор: Atala, Anthony Название: Principles of Regenerative Medicine ISBN: 0128098805 ISBN-13(EAN): 9780128098806 Издательство: Elsevier Science Рейтинг: Цена: 176290.00 T Наличие на складе: Поставка под заказ. Описание:
Principles of Regenerative Medicine, Third Edition, details the technologies and advances applied in recent years to strategies for healing and generating tissue. Contributions from a stellar cast of researchers cover the biological and molecular basis of regenerative medicine, highlighting stem cells, wound healing and cell and tissue development. Advances in cell and tissue therapy, including replacement of tissues and organs damaged by disease and previously untreatable conditions, such as diabetes, heart disease, liver disease and renal failure are also incorporated to provide a view to the future and framework for additional studies.
Автор: Appasani Название: Stem Cells & Regenerative Medicine ISBN: 1607618591 ISBN-13(EAN): 9781607618591 Издательство: Springer Рейтинг: Цена: 142830.00 T Наличие на складе: Есть Описание: Defined as, “The science about the development of an embryo from the fertilization of the ovum to the fetus stage,” embryology has been a mainstay at universities throughout the world for many years. Throughout the last century, embryology became overshadowed by experimental-based genetics and cell biology, transforming the field into developmental biology, which replaced embryology in Biology departments in many universities. Major contributions in this young century in the fields of molecular biology, biochemistry and genomics were integrated with both embryology and developmental biology to provide an understanding of the molecular portrait of a “development cell.” That new integrated approach is known as stem-cell biology; it is an understanding of the embryology and development together at the molecular level using engineering, imaging and cell culture principles, and it is at the heart of this seminal book. Stem Cells and Regenerative Medicine: From Molecular Embryology to Tissue Engineering is completely devoted to the basic developmental, cellular and molecular biological aspects of stem cells as well as their clinical applications in tissue engineering and regenerative medicine. It focuses on the basic biology of embryonic and cancer cells plus their key involvement in self-renewal, muscle repair, epigenetic processes, and therapeutic applications. In addition, it covers other key relevant topics such as nuclear reprogramming induced pluripotency and stem cell culture techniques using novel biomaterials. A thorough introduction to stem-cell biology, this reference is aimed at graduate students, post-docs, and professors as well as executives and scientists in biotech and pharmaceutical companies.
Автор: Goligorsky, Michael S. Название: Regenerative Nephrology ISBN: 0128101962 ISBN-13(EAN): 9780128101964 Издательство: Elsevier Science Рейтинг: Цена: 112290.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Progression of chronic diseases in general and chronic kidney disease in particular has been traditionally viewed in the light of various contributors to development of glomerulosclerosis and tubulointerstitial scarring culminating in renal fibrosis. Indeed, this dogma prevailed for decades underscoring experimental attempts to halt fibrotic processes. Breakthrough investigations of the past few years on stem/progenitor cell involvement in organ regeneration caused a conceptual shift in tackling the mechanisms of nephrosclerosis. It has become clear that the rate of progression of chronic kidney disease is the net sum of the opposing trends: degenerative fibrotic processes and regenerative repair mechanisms. The latter part of this equation has been by and large ignored for years and only recently attracted investigative attention. This book revisits the problem of kidney disease by focusing on regenerative mechanisms in renal repair and on the ways these regenerative processes can become subverted by an intrinsic disease process eventuating in its progression. Cutting-edge investigations are summarized by the most experienced international team of experts.
Автор: Cristian Riella, Peter G. Czarnecki, Theodore I. Steinman Название: Polycystic Kidney Disease ISBN: 161504762X ISBN-13(EAN): 9781615047628 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 41800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reviews important aspects of polycystic kidney diseases, the latest scientific understanding of the diseases and syndromes, along with the therapies being developed. Cystic kidney diseases comprise a spectrum of genetic syndromes defined by renal cyst formation and expansion with variable extrarenal manifestations. The most prevalent disorder is the autosomal dominant polycystic kidney disease.
Автор: Asok Mukhopadhyay Название: Regenerative Medicine: Laboratory to Clinic ISBN: 9811037000 ISBN-13(EAN): 9789811037009 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Поставка под заказ. Описание: It examines in detail the therapeutic application of hematopoietic stem cells in marrow regeneration, multi-potent mesenchymal stem cells (MSCs), also referred to as mesenchymal stromal cells.
Автор: Julie Audet; William L. Stanford Название: Stem Cells in Regenerative Medicine ISBN: 1617377848 ISBN-13(EAN): 9781617377846 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Here, leading experts in the field provide an updated representation of the landscape of stem cell-based therapies in a wide spectrum of tissue systems and ontogenic stages, from the isolation and culture of stem cells to their actual use in vivo.
Автор: Kursad Turksen Название: Bioprinting in Regenerative Medicine ISBN: 3319362941 ISBN-13(EAN): 9783319362946 Издательство: Springer Рейтинг: Цена: 113180.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Beginning with an overview, the discussion covers bioprinting in cell viability and pattern viability, tissue microfabrication to study cell proliferation, microenvironment for controlling stem cell fate, cell differentiation, zigzag cellular tubes, cartilage tissue engineering, osteogenesis, vessel substitutes, skin tissue and much more.
Автор: Juichi Ito Название: Regenerative Medicine for the Inner Ear ISBN: 443156389X ISBN-13(EAN): 9784431563891 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The research described in this book represents important steps toward understanding the development of inner ear medicine and new perspectives in regenerative medicine, including efficacy in cochlear implants and various other treatments.
Автор: Alice P?bay Название: Regenerative Biology of the Eye ISBN: 1493948636 ISBN-13(EAN): 9781493948635 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This text is a comprehensive look at the current knowledge on stem cell application for vision loss, showcasing different types of stem cells (adult, embryonic, iPSCs) for diseases of the front and the back of the eye.
Sherri M. Biendarra-Tiegs, Frank J. Secreto, and Timothy J. Nelson, M.D., Ph.D. Addressing variability and heterogeneity of induced pluripotent stem cell-derived cardiomyocytes
Justine Bajohr, Maryam Faiz Direct Lineage Reprogramming in the CNS
Yusuke Nakamura, Yasuo Shimizu Induced pluripotent stem cells for regenerative medicine: Quality control based on evaluation of lipid composition
Omair A. Mohiuddin, Brett Campbell, J. Nicholas Poche, Caasy Thomas-Porch, Daniel A. Hayes, Bruce A. Bunnell, Jeffrey M. Gimble Decellularized Adipose Tissue: Biochemical composition, in vivo analysis and potential clinical applications
Цzge Sezin SOMUNCUDECELLULARIZATION CONCEPT IN REGENERATIVE MEDICINE.
Janja Zupan, Matej Drobnič, Klemen Strazar Synovium-derived mesenchymal stem/ stromal cells and their promise for cartilage regeneration
Nur Kьbra Зankirili, Ozlem Altundag, Betьl Зelebi-Saltik Skin stem cells, their niche and tissue engineering approach for skin regeneration
Fatima Aerts-Kaya, Baris Ulum, Aynura Mammadova, Sevil Kцse, Gцzde Aydın, Petek Korkusuz, Duygu Uзkan-Зetinkaya. Neurological regulation of the bone marrow niche
Rokas Miksiunas, Ali Mobasheri Daiva Bironaite Homeobox genes and homeodomain proteins: new insights into cardiac development, degeneration and regeneration
Victor Navarro-Tableros, Yonathan Gomez, Maria Felice Brizzi Giovanni CamussiGeneration of human stem cell-derived pancreatic organoids (POs) for regenerative medicine
Автор: El-Badri Nagwa Название: Regenerative Medicine and Stem Cell Biology ISBN: 3030553582 ISBN-13(EAN): 9783030553586 Издательство: Springer Рейтинг: Цена: 74530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This textbook covers the basic aspects of stem cell research and applications in regenerative medicine. Each chapter includes a didactic component and a practical section. The book offers readers insights into: * How to identify the basic concepts of stem cell biology and the molecular regulation of pluripotency and stem cell development. * How to produce induced pluripotent stem cells (iPSCs) and the basics of transfection. * The biology of adult stem cells, with particular emphasis on mesenchymal stromal cells and hematopoietic stem cells, and the basic mechanisms that regulate them. * How cancer stem cells arise and metastasize, and their properties. * How to develop the skills needed to isolate, differentiate and characterize adult stem The clinical significance of stem cell research and the potential problems that need to be overcome. * Evaluating the use of stem cells for tissue engineering and therapies (the amniotic membrane) * The applications of bio-nanotechnology in stem cell research. * How epigenetic mechanisms, including various DNA modifications and histone dynamics, are involved in regulating the potentiality and differentiation of stem cells. * The scientific methods, ethical considerations and implications of stem cell research.
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