Mixed-Mode Chromatography: Principles, Methods, and Applications, Wan Qian-Hong
Автор: Zachariou Michael Название: Affinity Chromatography / Methods and Protocols ISBN: 1588296598 ISBN-13(EAN): 9781588296597 Издательство: Springer Рейтинг: Цена: 13330.00 T Наличие на складе: Есть Описание: Thirty-eight years after its introduction, affinity chromatography remains a key tool in th armory of separation techniques available to separation and interaction scientists. Expanded and updated from the first edition, this second edition volume aims to provide the beginner with the practical knowledge needed to develop affinity separations suitable for a variety of applications relevant to the post-genomic era.
Автор: Jones Oliver Название: Two-Dimensional Liquid Chromatography: Principles and Practical Applications ISBN: 9811561893 ISBN-13(EAN): 9789811561894 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book addresses the growing interest in the field of two-dimensional liquid chromatography (2DLC), a powerful approach to increasing resolution, available peak capacity, and selectivity in analytical chromatography.
Автор: Levitah Castil Mapatac Название: Chromatography: Concepts, Methods and Applications ISBN: 1680957228 ISBN-13(EAN): 9781680957228 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 141370.00 T Наличие на складе: Невозможна поставка. Описание: Provies an introduction to chromatography. Chromatography has become a cornerstone of separation science, that branch of chemistry devoted to separating compounds from mixtures. There are two main categories of chromatography: preparative and analytical. Analytical work uses small sample sizes; preparative work uses large quantities of samples and collects the output in bulk.
Автор: Percy Henrichon Название: Gas Chromatography: History, Methods and Applications ISBN: 1536173509 ISBN-13(EAN): 9781536173505 Издательство: Nova Science Рейтинг: Цена: 89750.00 T Наличие на складе: Невозможна поставка. Описание: Gas Chromatography: History, Methods and Applications focuses on the main applications of gas chromatography in clinical and forensic toxicology, mainly in the determination of drugs of abuse including the new psychoactive substances in several types of biological matrices. The authors go on to investigated the analysis of gaseous or volatile substances using sensor gas chromatography equipped with a semiconductor gas sensor detector. The simplicity, ease of handling, and high sensitivity of this method allow results to be obtained rapidly, which may provide valuable information for forensic diagnosis. This compilation addresses the way in which food adulteration practices are potentially harmful to human health and so food safety and authenticity constitute an important issue in food chemistry. The chemical composition of foodstuffs is an excellent indicator of quality, origin, authenticity and/or adulteration. The concluding study aims to determine the organic compounds of vinasse through gas chromatography-mass spectrometry GC-MS. Vinasse is a byproduct of ethanol and poses long-term risk to public health because of its persistent and toxic nature.
The first book dedicated to the emerging field of physiologically-based pharmacokinetic modeling (PBPK)
Now in its second edition, Physiologically Based Pharmacokinetic (PBPK) Modelling and Simulations: Principles, Methods, and Applications in the Pharma Industry remains the premier reference book throughout the rapidly growing PBPK user community. Using clear and concise language, author Sheila Annie Peters connects theory with practice as she explores the vast potential of PBPK modeling for improving drug discovery and development.
This fully updated new edition covers key developments in the field of PBPK modelling and simulations that have emerged in recent years. A brand-new section provides case studies in different application areas of PBPK modelling, including drug-drug interaction, genetic polymorphism, renal impairment, and pediatric extrapolation. Additional chapters address topics such as model-informed drug development (MIDD) and expose readers to a wide range of current applications in the field. Throughout the book, substantially revised chapters simplify complex topics and offer a balanced view of both the opportunities and challenges of PBPK modelling. Providing timely and comprehensive coverage of one of the most exciting new areas of pharmaceutical science, this book:
Describes the principles behind physiological modeling of pharmacokinetic processes, inter-individual variability, and drug interactions for small molecule drugs and biologics
Features a wealth of new figures and case studies of the applications of PBPK modelling along the value chain in drug discovery and development
Reflects the latest regulatory guidelines on the reporting of PBPK modelling analysis
Includes access to a new companion website containing code, datasets, explanations of case examples in the text, and discussion of key developments in the field
Contains a brief overview of the field, end-of-chapter keywords for easy reference, and an extensive bibliography
Physiologically-Based Pharmacokinetic (PBPK) Modeling and Simulations: Principles, Methods, and Applications in the Pharmaceutical Industry, Second Edition is an indispensable single-volume resource for beginning and intermediate practitioners across the pharmaceutical sciences in both industry and academia.
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
Автор: Goran Odham Название: Gas Chromatography Mass Spectrometry Applications in Microbiology ISBN: 1468445286 ISBN-13(EAN): 9781468445282 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: During recent years there has been increasing interest in the value of a number of chemical and physical-chemical analytical methods for the detection and characterization of microorganisms. Furthermore, such methods are currently used in studies on microbial metabolic processes, on the role of microorganisms in the turnover of inorganic and organic compounds, and on the impact on environmental changes by microbial activity. Moreover, the introduction of some of these methods not only shortens the analytical time period compared to ·'traditional" techniques, but also improves the analytical quality. Mass spectrometry (MS) combined with chromatographic inlet systems, particularly gas chromatography (GC), belongs to those methods which during recent years have established their value for the above-mentioned purposes. The present volume starts with basic chapters on the principles for MS and common inlet systems, particulary Gc. It discusses applications of these techniques to a number of microbiological disciplines, e.g., ecologi cal and medical microbiology. Emphasis is laid on organic compound classes vii viii / PREFACE of special relevance to microbiology, e.g., volatiles, lipids, amino acids, peptides and carbohydrates. Some compound classes of a more general biochemical rather than specific microbiological importance, e.g., steroids and nucleotides, are dealt with briefly. The editors wish to thank all those who have contributed to this book. We hope it will stimulate further research in this futuristic field and will be of practical value.
Автор: Adrianna Coty Название: Applications of Gas Chromatography ISBN: 1681172623 ISBN-13(EAN): 9781681172620 Издательство: Gazelle Book Services Рейтинг: Цена: 217350.00 T Наличие на складе: Невозможна поставка. Описание: Gas chromatography is a term used to describe the group of analytical separation techniques used to analyse volatile substances in the gas phase. In gas chromatography, the components of a sample are dissolved in a solvent and vaporised in order to separate the analyses by distributing the sample between two phases: a stationary phase and a mobile phase. The mobile phase is a chemically inert gas that serves to carry the molecules of the analyse through the heated column. Gas chromatography is one of the sole forms of chromatography that does not utilise the mobile phase for interacting with the analyse. The stationary phase is either a solid adsorbent, termed gas-solid chromatography (GSC), or a liquid on an inert support, termed gas-liquid chromatography (GLC). Helium remains the most commonly used carrier gas in about 90% of instruments although hydrogen is preferred for improved separations. This inert gas goes through a glass column packed with silica that is coated with a liquid. Materials that are less soluble in the liquid will increase the result faster than the material with greater solubility. The purpose of this book is to provide a better understanding on its separation and measurement techniques and its application. Since chromatography techniques are separating and analysing methods, this book will help other researchers and young scientists to choose a suitable chromatography technique. Furthermore, this book illustrates the newest challenges in this area. This valuable book aims to provide a connection between various chromatography techniques and different processes.
Автор: White, Robert Название: Chromatography/Fourier Transform Infrared Spectroscopy and its Applications ISBN: 0367450887 ISBN-13(EAN): 9780367450885 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is intended to serve as an up-to-date reference source for those familiar with chromatography/Fourier transform infrared spectroscopy (FT-IR) methods and as an introduction to techniques and applications for those interested in future uses for chromatography/FT-IR.
This is the first book that comprehensively and systematically describes the new technology of hydrophilic interaction liquid chromatography (HILIC). Hydrophilic interaction chromatography is a separation technique suitable for polar and hydrophilic compounds and orthogonal to reversed phase liquid chromatography. From small organic molecules to proteins, the text explores the many applications of HILIC in the analytical field. Winner of the President's Award for Excellence, the author explains how HILIC can significantly improve analytical throughput by shortening sample preparation procedure, which is one of the bottlenecks for drug discovery and development in the pharmaceutical industry.
Автор: Mikolaj Tosto Название: Marine Glycobiology: Principles & Applications ISBN: 1681176890 ISBN-13(EAN): 9781681176895 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, which is the study of the structure and function of carbohydrates and carbohydrate containing molecules, is fundamental to all biological systems. Progress in glycobiology has shed light on a range of complex biological processes associated with, disease and immunology, molecular and cellular communication, and developmental biology. Marine Glycobiology: Principles and Applications revolutionise the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships. In fact, glycobiology combines all branches of biomedical research, revealing the vast and diverse forms of carbohydrate structures that exist in nature. Advances in structure determination have enabled scientists to study the function of complex carbohydrates in more depth and to determine the role that they play in a wide range of biological processes. Glycobiology research in marine systems has primarily focused on reproduction, in particular for what concern the chemical communication between the gametes. There is an established, if rather modest, tradition of glycobiology research in marine systems that have primarily focused on reproduction, biofouling, and chemical communication. The current status of marine glycobiology is mainly descriptive with very limited progress on structural clarification and the consequent definition of specific functional roles beyond a small number of classical examples, (eg: induction of the acrosome reaction in echinoderms). However, with recent advances in analytical instrumentation, there is now the capacity to begin to characterise marine glycoconjugates, many of which will have potential biomedical and biotechnological applications. This title will highlight the fundamental importance of glycobiology for many biological processes in marine organisms and will draw upon the best defined systems. These systems therefore may prove genuine candidates for full carbohydrate characterisation.
Автор: Ruifu Yang Название: Principles and Applications of Up-converting Phosphor Technology ISBN: 9813292784 ISBN-13(EAN): 9789813292789 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents an overview of up-converting phosphor (UCP), including UCP preparation, development of the rapid detection strips and UCP industrialization. It also discusses the wide clinical applications of this technology, such as in food poisoning, infectious diseases, drug-abuse and disaster rescue, where rapid point-of-care testing is often critical. Conventional testing methods are mainly based on gold immunochromatography, which relies heavily on results being read with the naked eye. However, up-converting phosphor technology (UPT) employs UCP particles as labels for rapid target detection. Unlike other conventional fluorescence techniques, UCP is excited by infrared light and emitted visible light. This anti-stokes phenomenon provides this special label with significant advantages, including zero background detection, high resistance to environmental influences (e.g. pH, salts, sample contamination), high sensitivity and quantitative detection.Systematically summarizing UCP technology and its wide applications, this book is a valuable resource for researchers and technicians in the field.
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