Antimalarial Natural Products, Kinghorn A. Douglas, Falk Heinz, Gibbons Simon
Автор: Patrick, Graham Название: The Design and Synthesis of Antimalarial Agents ISBN: 0081012101 ISBN-13(EAN): 9780081012109 Издательство: Elsevier Science Рейтинг: Цена: 179660.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
The Design and Synthesis of Antimalarial Agents is a comprehensive yet accessible guide for all those involved in the design, development and administration of antimalarial drugs. The book aims to support medicinal chemists in the search for improved and novel antimalarial drugs, providing practical guidance on current developments and highlighting promising leads. Beginning with a focus on biological aspects of malaria, early chapters include a description of the lifecycle of the parasite responsible for malaria, the problem of resistance, combinational therapy, genetic mapping of the parasite's genome, established drug targets, and potential drug targets for the future.
Malaria is a deadly disease which threatens half of the world's population. Advances over the last decade have seen vast improvements in the effectiveness of both preventative measures and treatments, but the rapid adaptability of the disease means that the ongoing search for improved and novel antimalarial drugs is essential.
The Design and Synthesis of Antimalarial Agents covers the medicinal chemistry of antimalarial agents in detail, with a focus on the design of antimalarial drugs supported by a review of the drug categories that have reached the market, as well as those in the pipeline. Finally, the synthesis of different classes of antimalarial agents is reviewed, including a discussion on chemical and process development.
Consolidates current developments in the discovery, design, and synthesis of antimalarial drugs for the first time
Presents content in a style that is both thorough and engaging, supporting and encouraging students and researchers from interdisciplinary backgrounds
Highlights which drug targets are currently considered to be the most promising for future therapies, and the classes of compounds that are currently being studied and perfected
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