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Proteostasis and proteolysis, 


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Название:  Proteostasis and proteolysis
ISBN: 9780367499327
Издательство: Taylor&Francis
Классификация:


ISBN-10: 0367499320
Обложка/Формат: Hardcover
Страницы: 251
Вес: 0.65 кг.
Дата издания: 23.11.2021
Серия: Oxidative stress and disease
Язык: English
Иллюстрации: 9 tables, black and white; 21 line drawings, color; 28 line drawings, black and white; 4 halftones, color; 25 illustrations, color; 28 illustrations, black and white
Размер: 183 x 262 x 20
Читательская аудитория: Postgraduate, research & scholarly
Рейтинг:
Поставляется из: Европейский союз
Описание: Proteostasis integrates biological pathways controlling biogenesis, trafficking, folding, and degradation of proteins. This book focuses on two protein breakdown/degradation processes (proteolysis), which are part of a normally functioning proteostatic system: the ubiquitin-proteasome system and autophagy.

Proteostasis and Chaperone Surveillance

Автор: Laishram Rajendrakumar Singh; Tanveer Ali Dar; Par
Название: Proteostasis and Chaperone Surveillance
ISBN: 8132234545 ISBN-13(EAN): 9788132234548
Издательство: Springer
Рейтинг:
Цена: 104480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proteostasis is central to the development of various human diseases caused due to excessive protein misfolding and the disregulation of the protein quality control system.

Neurodegeneration: Metallostasis and Proteostasis

Автор: Milardi Danilo
Название: Neurodegeneration: Metallostasis and Proteostasis
ISBN: 1849730504 ISBN-13(EAN): 9781849730501
Издательство: Royal Society of Chemistry
Рейтинг:
Цена: 171760.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This exemplary book gives an up-to-date perspective on the role of metal ions in neurodegeneration.

Proteostasis

Автор: Matthiesen
Название: Proteostasis
ISBN: 1493937545 ISBN-13(EAN): 9781493937547
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume highlights the role of proteostasis in human health and associated disease model systems, reflecting its rising importance which has led to the development of new technologies to obtain insight into underling protein mechanistic events. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Authoritative and cutting-edge, Proteostasis: Methods and Protocols aims to become a reference book on proteostasis in human health.


Regulated Proteolysis in Microorganisms

Автор: David A. Dougan
Название: Regulated Proteolysis in Microorganisms
ISBN: 9400759398 ISBN-13(EAN): 9789400759398
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker`s yeast Saccharomyces cerevisiae).

Proteasomes: The World of Regulatory Proteolysis

Автор: Hilt, Wolfgang
Название: Proteasomes: The World of Regulatory Proteolysis
ISBN: 1587060116 ISBN-13(EAN): 9781587060113
Издательство: Taylor&Francis
Рейтинг:
Цена: 193950.00 T
Наличие на складе: Нет в наличии.

Regulated Proteolysis in Microorganisms

Автор: David A. Dougan
Название: Regulated Proteolysis in Microorganisms
ISBN: 9401783667 ISBN-13(EAN): 9789401783668
Издательство: Springer
Рейтинг:
Цена: 148010.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book contains an extensive collection of critical reviews, from leading researchers in the field of regulated protein degradation. It covers the role of regulated proteolysis in a range of microorganisms (from Gram positive, Gram negative and pathogenic bacteria to Archaea and the Baker s yeast Saccharomyces cerevisiae)."

Analysis of Post-Translational Modifications and Proteolysis in Neuroscience

Автор: Jennifer Elizabeth Grant; Hong Li
Название: Analysis of Post-Translational Modifications and Proteolysis in Neuroscience
ISBN: 1493980580 ISBN-13(EAN): 9781493980581
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

1. Proteomic Analysis of Post-Translational Modifications in Neurobiology

Hongbo Gu, Matthew P. Stokes, and Jeffrey C. Silva

2. A Boronic Acid-based Enrichment for Site-specific Identification of the N-glycoproteome using MS-based Proteomics

Haopeng Xiao, George X. Tang, Weixuan Chen, and Ronghu Wu

3. Site-specific Localization of D-Amino Acids in Bioactive Peptides by Ion Mobility Spectrometry

Chenxi Jia, Christopher B. Lietz, Qing Yu, and Lingjun Li

4. Quantitative Profiling of Reversible Cysteome Modification under Nitrosative Stress

Yue-Ting Wang, Sujeewa C. Piyankarage, and Gregory R. J. Thatcher

5. Label-free LC-MS/MS Comparative Analysis of Protein S-nitrosome in Synaptosomes from Wild Type and APP Transgenic Mice

Monika Zaręba-Koziol, Maciej Lalowski, and Aleksandra Wyslouch-Cieszyńska

6. Proteomics Identification of Redox-Sensitive Nuclear Protein Targets Of Human Thioredoxin 1 from SHSY-5Y Neuroblastoma Cell Line

Mohit Raja Jain, Changgong Wu, Qing Li, Chuanlong Cui, Huacheng Dai, and Hong Li

7. Identification and Quantification of K63-Ubiquitinated Proteins in Neuronal Cells by Hi

gh-

Resolution Mass Spectrometry

Gustavo Monteiro Silva, Wei Wei, Sandhya Manohar, and Christine Vogel

8. Phosphorylation Site Profiling of NG108 Cells Using Quadrupole/Orbitrap Mass

Spectrometry

Fang-Ke Huang, Guoan Zhang, and Thomas A. Neubert

9. Phosphoproteomics of Tyrosine Kinases in the Nervous System

Robert J. Chalkley and

Ralph A. Bradshaw

10. Analysis of PINK1 and CaMKII Substrates Using Mass Spectrometry-Based Proteomics

Yan Li, Lesley A. Kane, Michael A Bemben, and Katherine W Roche

11. Liquid Chromatography-Tandem Mass Spectrometry Analysis of Tau Phosphorylation

Jhoana Mendoza, Georgia Dolios, and Rong Wang

12. Identification of Protease Substrates in Complex Proteomes by iTRAQ-TAILS

Tobias Kockmann, Nathalie Carte, Samu Melkko, and Ulrich auf dem Keller

13. Proteolytic P

rocessing of Neuropeptides

Lloyd D. Fricker

14 Isotope Dilution Analysis of Myelin Basic Protein Degradation after Brain Injury

Andrew K Ottens

15. Identification and Characterization of Protein Post-Translational Modifications by

Differential Fluorescent Labeling

Eric D. Hamlett, Cristina Osorio, and Oscar Alzate

16 Mass

Spectrometric Detection of Detyrosination and Polyglutamyation on the C-Terminal Region of Brain Tubulin

Yasuko Mori, Alu Konno, Mitsutoshi Setou, and Koji Ikegami

17. Determination of polyhydroxybutyrate (PHB) Post-Translational Modifications of Proteins Using Mass Spectrometry

Tong Liu, Wei Chen, Stacey Pan, Chuanlong Cui, Hong Li, and Eleonora Zakharian


Bioactive Peptides Produced by Limited Proteolysis

Автор: C. M. Camargo, Beatriz L. Fernandes, Lilian Cruz
Название: Bioactive Peptides Produced by Limited Proteolysis
ISBN: 1615043683 ISBN-13(EAN): 9781615043682
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 41580.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proteins are considered supremely important for the organization, survival, and functioning of living organisms. They were considered stable and static molecules until the early 1940s, when Rudolph Schoenheimer demonstrated that proteins exist in a constant dynamic process of synthesis and degradation (proteostasis), absolutely essential for life. Since then, general and limited protein degradation became some of the most fascinating aspects of biological sciences. This book is focused on a particular aspect of protein degradation, namely, limited proteolysis, which gives rise to bioactive peptides as a result of the enzymatic action of proteinases and peptidases, which are enzymes that hydrolyze specific peptide bonds of proteins and peptides, respectively. In a broad sense, bioactive peptides are any fragment of endogenous or exogenous proteins able to elicit either physiological or pathological activities. Here, we aim at presenting to the readers that bioactive peptides are not merely produced through random processes during protein degradation, but rather through a well-organized enzymatic process that is deeply integrated in the homeostatic processes of living organisms.

Chemistry of Proteolysis

Автор: Vladimir K. Antonov
Название: Chemistry of Proteolysis
ISBN: 3662009811 ISBN-13(EAN): 9783662009819
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A first edition of this book appeared in Russian language in 1983. The book retains the presentation of the previous edition and yet enlarges the scope to cover the methods for site-directed mutagenesis of amide hydrolases, catalyti- cally active antibodies, etc.

Proteolysis in the Interstitial Space

Автор: Pizzo, Salvatore V.
Название: Proteolysis in the Interstitial Space
ISBN: 0367736985 ISBN-13(EAN): 9780367736989
Издательство: Taylor&Francis
Рейтинг:
Цена: 48990.00 T
Наличие на складе: Нет в наличии.

Analysis of Post-Translational Modifications and Proteolysis in Neuroscience

Автор: Grant
Название: Analysis of Post-Translational Modifications and Proteolysis in Neuroscience
ISBN: 1493934708 ISBN-13(EAN): 9781493934706
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume highlights proteomics studies of quantitative PTM changes in both peripheral and central nervous system proteomes utilizing the most recent advances in mass spectrometry. Chapters include practical information pertaining to the fundamentals of sample preparation, liquid chromatography, and tandem mass spectrometry instrumental analysis and will elucidate best practices in the interpretation of data using modern bioinformatics approaches. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Analysis of Post-Translational Modifications and Proteolysis in Neuroscience aims to ensure successful results in the further study of this vital field.

Specificity of Proteolysis

Автор: Borivoj Keil
Название: Specificity of Proteolysis
ISBN: 3642483828 ISBN-13(EAN): 9783642483820
Издательство: Springer
Рейтинг:
Цена: 104480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Specificity of Proteolysis presents a survey and conclusionson the action or proteinases - enzymes which are cleavingproteins or peptides. Whenever one is lookingfor an enzyme to act at a defined site or to give definedcleavage products one will find comprehensive information inthis work.


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