Neurodegenerative Diseases Biomarkers: Towards Translating Research to Clinical Practice, Peplow Philip V., Martinez Bridget, Gennarelli Thomas A.
Автор: Kovacs Название: Neuropathology of Neurodegenerative Diseases Book and Online ISBN: 1107442427 ISBN-13(EAN): 9781107442429 Издательство: Cambridge Academ Рейтинг: Цена: 93990.00 T Наличие на складе: Поставка под заказ. Описание: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases. The book is packaged with a password, giving the user online access to all the text and images.
Автор: Md. Sahab Uddin, Ghulam Md Ashraf Название: Quality Control of Cellular Protein in Neurodegenerative Disorders ISBN: 1799813177 ISBN-13(EAN): 9781799813170 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 264270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A hallmark of neurodegenerative proteinopathies is the formation of misfolded protein aggregates that cause cellular toxicity. Though multiple factors like aging, oxidative stress, gene inconsistency, etc. are responsible for the dysfunction of the protein quality control system, targeting protein quality control has become an auspicious approach to block the propagation of neurodegeneration.
Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the theoretical and practical methods of protein quality control systems and potential therapeutic approaches to halt the development and propagation of neurodegenerative disorders. Featuring coverage on a broad range of topics such as cellular chaperones, protein folding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.
Автор: Giuseppe Legname, Gabriele Giachin Название: Prion Phenomena in Neurodegenerative Diseases: New Frontiers in Neuroscience ISBN: 1634833996 ISBN-13(EAN): 9781634833998 Издательство: Nova Science Цена: 211200.00 T Наличие на складе: Невозможна поставка. Описание: The most fascinating and unique feature of prion diseases is that they are caused almost exclusively by a proteinaceous and infectious particle termed prions by the Nobel Prize laureate S B Prusiner, who discovered this class of pathogens. In the latter part of the 1990s, mad-cow disease, a disease caused by prions acquired through foodborne transmission, raised unprecedented public concern due to the concrete possibility that prions in animals could be transmitted to humans through the food chain. For roughly two decades, prions were under intense scrutiny and many studies were undertaken worldwide. These investigations have led our community to a better risk assessment and management of prion diseases in humans and in animals, substantially limiting the possibility of new prion epidemics. Nowadays, prions have been brought once again to the foreground after the discovery that a variety of neurodegenerative diseases, in particular Alzheimers disease, Parkinsons disease and amyotrophic lateral sclerosis, share fundamental features with prions, including protein misfolding and aggregation in the brain, cell-to-cell transmission and in vivo infectivity. Therefore, studying prions might help to understand the pathological mechanism of these disorders. The Prion Phenomena In Neurodegenerative Diseases: New Frontiers in Neuroscience is a book that benefits from the contribution of leading scientists in different fields of neuroscience, including Gianluigi Zanusso, Holger Wille, Fabrizio Tagliavini, Andrew F Hill, Jerson L Silva, Vladimir N Uversky, Henrike Heise, David W Colby, Neil R Cashman and the Nobel Prize laureate Eric R Kandel. This chapter collection discusses the development of prions and their various diseases, and provides a detailed overview about the state of the art of the novel prion phenomena observed in other fatally damaging protein misfolding disorders. This book represents an up-to-date review of different protein-misfolding diseases, serving as an invaluable tool for both specialized researchers working in the field of neurodegeneration and for a broad spectrum of academic readers that wish to learn more about the prion phenomena.
Автор: Obulesu, Magisetty (regional Agricultural Research Station, Acharya N.g. Ranga Agricultural University, Tirupati, India) Название: Plant extracts in neurodegenerative diseases ISBN: 0323957625 ISBN-13(EAN): 9780323957625 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Let`s Learn About the Forest is an interactive oversized board book that encourages little ones to use their imaginations and power of discovery to find the different animals and items in the forest God created. As they do, they will also learn interesting facts about the different animals and their habitats.
Автор: Md. Sahab Uddin, Md. Shah Amran Название: Handbook of Research on Critical Examinations of Neurodegenerative Disorders ISBN: 1522552820 ISBN-13(EAN): 9781522552826 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 288420.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Neurodegeneration is a key feature of several diseases that are referred to as neurodegenerative diseases. The process of neurodegeneration is not well-understood so the diseases that stem from it have, as yet, no cures. As such, studying the effects of these disorders can provide insight into the treatment, prevention, and future opportunities and challenges in this growing field.The Handbook of Research on Critical Examinations of Neurodegenerative Disorders is a critical scholarly resource that provides an extensive explanation of various neurodegenerative disorders based on existing studies to clarify etiology, pathological mechanisms, diagnosis, therapeutic interventions, as well as current status and future opportunities and challenges. Featuring coverage on a broad range of topics such as dementia, mitochondrial dysfunction, and risk factors, this book is geared towards neurobiologists, neuropsychologists, neurophysiologists, neuropathologists, medical professionals, academicians, and researchers seeking research on the complexity of neurodegenerative disorders.
Human Caspases and Neuronal Apoptosis in Neurodegenerative Diseases elucidates elaborately the role of caspase enzymes implicated in the initiation of molecular events leading to neuronal apoptosis in the neurodegenerative disease. The book starts with introduction to neuropathology, neurogenetics, and epidemiology of neurodegenerative disease and illustrates the involvement of human caspases, neuronal apoptosis, apoptotic pathways, genetic polymorphisms, and several other factors and underlying mechanisms in the pathology of Alzheimer's disease, Parkinson's disease, and Huntington's disease. An important focus in all chapters is the intricate mechanisms and interplay that occur during or leading to neuron death in neurodegenerative diseases, along with disease pathobiology.
Автор: Obulesu, Magisetty (regional Agricultural Research Station, Acharya N.g. Ranga Agricultural University, Tirupati, India) Название: Turmeric and curcumin for neurodegenerative diseases ISBN: 0128224487 ISBN-13(EAN): 9780128224489 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Поставка под заказ. Описание: Discover new places with fully updated road atlases from Collins. Full colour map of Ireland at 9 miles to 1 inch (1:570,240), with clear, detailed road network and counties and new administrative areas shown in colour. This double-sided map covers the whole of Ireland, and is ideal for reference or route planning.
Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer's and Parkinson's, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer's Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more.
Summarizes the current status of and future research in Alzheimer's and Parkinson's diseases
Reviews the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases.
Автор: Gary Fiskum Название: Neurodegenerative Diseases ISBN: 1489902112 ISBN-13(EAN): 9781489902115 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the Fifteenth Washington International Spring Symposium held at The George Washington University, Washington, D.C., May 15-17, 1995
Автор: Verkhratsky Alexei, Ho Margaret S., Zorec Robert Название: Neuroglia in Neurodegenerative Diseases ISBN: 9811399158 ISBN-13(EAN): 9789811399152 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a comprehensive overview of the role of neuroglia in neurodegenerative diseases. In addition, to highlight the function of neuroglia in different types of neurodegenerative disease, it also discusses their mechanisms and effects on protecting or damaging neurons.
Автор: Theresa Natalie Название: Encyclopedia of Neurodegenerative Diseases: Volume VI (Advanced Researches) ISBN: 1632411814 ISBN-13(EAN): 9781632411815 Издательство: Неизвестно Цена: 110350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides an extensive account of various diseases, such as Parkinson's disease, prion disease, motor neuron diseases like multiple sclerosis and spinal muscular atrophy. It also offers a profound explanation of various neurodegenerative diseases
Автор: Yadav, Awesh K. Название: Nanomedical Drug Delivery For Neurodegenerative Diseases ISBN: 032385544X ISBN-13(EAN): 9780323855440 Издательство: Elsevier Science Рейтинг: Цена: 174050.00 T Наличие на складе: Поставка под заказ. Описание: When opposites attract...? In this Portland Midwives story, midwife Hazel is not looking for a relationship. So, why is she so drawn to Dr Caleb? Especially when he`s from the hospital that delayed the opening of her birthing centre. The enigmatic surgeon knows just how to push all her buttons...and sparks soon fly in every direction!
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