Описание:
Dedication
Acknowledgements
Preface
1 Introduction
Part I
How drugs are discovered and developed in the pharmaceutical industry
2 Introduction to drugs and drug targets
3 Background to chemistry of small and large molecules
4 Laying the foundations- Drug discovery from antiquity to the twenty first century
Part II
The drug development pipeline - discovery to testing in humans
5 Drug discovery pipeline overview 6 Target discovery
7 Medicinal chemistry
8 Biotherapeutics
9 Screening for hits
10 Process chemistry and formulation
11 Preclinical development
Part III
The drug development pipeline - clinical trials to marketing authorisation
12 Clinical trials
13 Regulatory affairs and marketing approval
14 Diagnostics and personalized medicine
15 Putting it All Together: a drug development case history
Part IV
The Global Pharmaceuticals Business
16 Commercial aspects of drug development
17 Challenges and responses
Part V
Professional Interactions with the Drug Discovery Industry
18 Professional Interactions with the Drug Discovery Industry: Technology Transfer Executives
19 Recruitment Executives
20 Pharmaceutical translators and Interpreters
Appendix 1 Further Reading
Appendix 2 Glossary of terms
