Philosophy of molecular medicine, 

Автор: Baetu Tudor
Название: Mechanisms in Molecular Biology
ISBN: 1108742300 ISBN-13(EAN): 9781108742306
Издательство: Cambridge Academ
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Цена: 19010.00 T
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Описание: In this Element, Tudor Baetu explores the metaphysical inquiry into how mechanisms relate to issues such as causation, capacities and levels of organization, and epistemic issues related to the discovery of mechanisms and the intelligibility of mechanistic representations. He shows how the gap between them can be bridged.

Автор: Noble
Название: Dance to the Tune of Life
ISBN: 1107176247 ISBN-13(EAN): 9781107176249
Издательство: Cambridge Academ
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Цена: 24280.00 T
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Описание: Challenging the common gene-centric approach to organisms, this book articulates a relativistic theory of biology. It is grounded in up-to-date biological research and rigorous application of mathematics to biology; however, it is presented in a non-technical manner for the general reader, and requires no familiarity with complex biology, mathematics or philosophy.

Автор: Minelli, Alessandro
Название: Understanding development
ISBN: 110879923X ISBN-13(EAN): 9781108799232
Издательство: Cambridge Academ
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Цена: 12660.00 T
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Описание: Using familiar examples and easy-to-follow arguments, this concise book offers fresh alternatives to a number of widespread misconceptions about development. It will appeal to anyone interested in novel views and ideas in biology, including biologists, science educators, philosophers, students and general readers.

Автор: Arthur, Wallace (national University Of Ireland, Galway)
Название: Understanding evo-devo
ISBN: 110881946X ISBN-13(EAN): 9781108819466
Издательство: Cambridge Academ
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Цена: 12660.00 T
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Описание: A brief and accessible account of evolutionary developmental biology, `evo-devo`, for anyone intrigued by this exciting interdisciplinary field, including biological science students and general readers. It covers all key themes, including: developmental bias, toolkit genes, gene co-option, and the origins of evolutionary novelties and body plans.

Название: The Future of Scientific Practice
ISBN: 1138706426 ISBN-13(EAN): 9781138706422
Издательство: Taylor&Francis
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Цена: 54090.00 T
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Описание: Focusing on cell dynamics, molecular medicine and robotics, contributors explore the interplay between biological, technological and theoretical ways of thinking. The collection makes a strong contribution to current debates in the philosophy of science and the changing role of scientific practice.

Автор: Bertolaso
Название: The Future of Scientific Practice
ISBN: 1848935625 ISBN-13(EAN): 9781848935624
Издательство: Taylor&Francis
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Цена: 158230.00 T
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Описание: Focusing on cell dynamics, molecular medicine and robotics, contributors explore the interplay between biological, technological and theoretical ways of thinking. The collection makes a strong contribution to current debates in the philosophy of science and the changing role of scientific practice.

Название: Philosophy of molecular medicine
ISBN: 1138940674 ISBN-13(EAN): 9781138940673
Издательство: Taylor&Francis
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Цена: 158230.00 T
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Описание: Philosophy of Molecular Medicine: Foundational Issues in Theory and Practice aims at a systematic investigation of a number of foundational issues in the field of molecular medicine. The volume is organized around four broad modules focusing, respectively, on the following key aspects: What are the nature, scope, and limits of molecular medicine? How does it provide explanations? How does it represent and model phenomena of interest? How does it infer new knowledge from data and experiments? The essays collected here, authored by prominent scientists and philosophers of science, focus on a handful of mainstream topics in the philosophical literature, such as causation, explanation, modeling, and scientific inference. These previously unpublished contributions shed new light on these traditional topics by integrating them with problems, methods, and results from three prominent areas of contemporary biomedical science: basic research, translational and clinical research, and clinical practice.

Автор: Stanley Shostak
Название: Death of Life
ISBN: 1349137049 ISBN-13(EAN): 9781349137046
Издательство: Springer
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Цена: 130430.00 T
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Описание: The Death of Life dissects biology`s claim to be the Cinderella science that rose above its station. Early attempts to study life through observation, experiment and theory are exposed as the skeleton of ideas for controlling life, ideas which were only fleshed out by the biotech and genomic industries.

Автор: Wallace Arthur
Название: Understanding Evo-Devo
ISBN: 1108836933 ISBN-13(EAN): 9781108836937
Издательство: Cambridge Academ
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Цена: 49620.00 T
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Описание: A brief and accessible account of evolutionary developmental biology, `evo-devo`, for anyone intrigued by this exciting interdisciplinary field, including biological science students and general readers. It covers all key themes, including: developmental bias, toolkit genes, gene co-option, and the origins of evolutionary novelties and body plans.

Автор: Smith, George E.
Название: Brownian motion and molecular reality :
ISBN: 0190098023 ISBN-13(EAN): 9780190098025
Издательство: Oxford Academ
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Цена: 92930.00 T
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Описание: Between 1905 and 1913, French physicist Jean Perrin's experiments on Brownian motion ostensibly put a definitive end to the long debate regarding the real existence of molecules, proving the atomic theory of matter. While Perrin's results had a significant impact at the time, later examination
of his experiments questioned whether he really gained experimental access to the molecular realm. The experiments were successful in determining the mean kinetic energy of the granules of Brownian motion; however, the values for molecular magnitudes Perrin inferred from them simply presupposed
that the granule mean kinetic energy was the same as the mean molecular kinetic energy in the fluid in which the granules move. This stipulation became increasingly questionable in the years between 1908 and 1913, as significantly lower values for these magnitudes were obtained from other
experimental results like alpha-particle emissions, ionization, and Planck's blackbody radiation equation.

In this case study in the history and philosophy of science, George E. Smith and Raghav Seth here argue that despite doubts, Perrin's measurements were nevertheless exemplars of theory-mediated measurement-the practice of obtaining values for an inaccessible quantity by inferring them from an
accessible proxy via theoretical relationships between them. They argue that it was actually Perrin more than any of his contemporaries who championed this approach during the years in question. The practice of theory-mediated measurement in physics had a long history before 1900, but the concerted
efforts of Perrin, Rutherford, Millikan, Planck, and their colleagues led to the central role this form of evidence has had in microphysical research ever since. Seth and Smith's study thus replaces an untenable legend with an account that is not only tenable, but more instructive about what the
evidence did and did not show.

Автор: Antonio Lima-de-Faria
Название: Molecular Origins of Brain and Body Geometry
ISBN: 3319060554 ISBN-13(EAN): 9783319060552
Издательство: Springer
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Цена: 139750.00 T
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Описание: New concepts arise in science when apparently unrelated fields of knowledge are put together in a coherent way. The recent results in molecular biology allow to explain the emergence of body patterns in animals that before could not be understood by zoologists. There are no ”fancy curiosities” in nature. Every pattern is a product of a molecular cascade originating in genes and a living organism arises from the collaboration of these genes with the outer physical environment. Tropical fishes are as startling in their colors and geometric circles as peacocks. Tortoises are covered with the most regular triangles, squares and concentric circles that can be green, brown or yellow. Parallel scarlet bands are placed side by side of black ones along the body of snakes. Zebras and giraffes have patterns which are lessons in geometry, with their transversal and longitudinal stripes, their circles and other geometric figures. Monkeys, like the mandrills, have a spectacularly colored face scarlet nose with blue parallel flanges and yellow beard. All this geometry turns out to be highly molecular. The genes are many and have been DNA sequenced. Besides they not only deal with the coloration of the body but with the development of the brain and the embryonic process. A precise scenario of molecular events unravels in the vertebrates. It may seem far-fetched, but the search for the origin of this geometry made it mandatory to study the evolution of matter and the origin of the brain. It turned out that matter from its onset is pervaded by geometry and that the brain is also a prisoner of this ordered construction. Moreover, the brain is capable of altering the body geometry and the geometry of the environment changes the brain. Nothing spectacular occurred when the brain arrived in evolution. Not only it came after the eye, which had already established itself long ago, but it had a modest origin. It started from sensory cells on the skin that later aggregated into clusters of neurons that formed ganglia. It also became evident that pigment cells, that decide the establishment of the body pattern, originate from the same cell population as neurons (the neural crest cells). This is a most revealing result because it throws light on the power that the brain has to rapidly redirect the coloration of the body and to change its pattern. Recent experiments demonstrate how the brain changes the body geometry at will and within seconds, an event that could be hardly conceived earlier. Moreover, this change is not accidental it is related to the surrounding environment and is also used as a mating strategy. Chameleons know how to do it as well as flat fishes and octopuses. No one would have dared to think that the brain had its own geometry. How could the external geometry of solids or other figures of our environment be apprehended by neurons if these had no architecture of their own? Astonishing was that the so called ”simple cells”, in the neurons of the primary visual cortex, responded to a bar of light with an axis of orientation that corresponded to the axis of the cell’s receptive field. We tend to consider our brain a reliable organ. But how reliable is it? From the beginning the brain is obliged to transform reality. Brain imagery involves: form, color, motion and sleep. Unintentionally these results led to unexpected philosophical implications. Plato’s pivotal concept that ”forms” exist independently of the material world is reversed. Atoms have been considered to be imaginary for 2,000 years but at present they can be photographed, one by one, with electron microscopes. The reason why geometry has led the way in this inquiry is due to the fact that where there is geometry there is utter simplicity coupled to rigorous order that underlies the phenomenon where it is recognized. Order allows variation but imposes at the same time a canalization that is patent in what we call evolution.

Автор: Alessandro Minelli
Название: Understanding Development
ISBN: 1108836771 ISBN-13(EAN): 9781108836777
Издательство: Cambridge Academ
Рейтинг:
Цена: 49620.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Using familiar examples and easy-to-follow arguments, this concise book offers fresh alternatives to a number of widespread misconceptions about development. It will appeal to anyone interested in novel views and ideas in biology, including biologists, science educators, philosophers, students and general readers.