Genomic Diversity in People of India: Focus on Mtdna and Y-Chromosome Polymorphism, Anthropological Survey Of India

Автор: Anthropological Survey of India
Название: Genomic Diversity in People of India
ISBN: 9811601658 ISBN-13(EAN): 9789811601651
Издательство: Springer
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Описание: This book is the output of Anthropological Survey of India`s National Project "DNA Polymorphism of Contemporary Indian Population" conducted during 2000 to 2018.

Автор: Wyandt
Название: Human Chromosome Variation: Heteromorphism and Polymorphism
ISBN: 9400708955 ISBN-13(EAN): 9789400708952
Издательство: Springer
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Описание: Human Chromosome Variation: Heteromorphism and Polymorphism was formerly printed under the title “Atlas of Human Chromosome Heteromorphism”. The Atlas has become a standard reference book in most cytogenetic laboratories and is cited as a significant reference in ISCN 2009. This revised version has updated and retained the most useful pictorial sections of the first edition, including the comprehensive review of normal and “not-so-normal” variations of the human karyotype with summaries and extensive reference lists organized by chromosome number. This updated edition features concise background information on chromosome methods and applications, essential information on heteromorphism frequencies in normal and clinical populations as well as new listing and discussions of euchromatic, subtelomeric and FISH variants. The addition of two new sections make this an even more valuable reference than before. A section on common and rare fragile sites includes a short historical discussion, definitions and an extensive table of officially recognized sites that includes the HUGO name, chromosomal location, methods of induction, genes and references to the most recent molecular characterization. A new section on array CGH discusses the clinical challenge of interpreting copy number variations (CNVs) revealed by this newest technology, gives examples of various levels of interpretation and lists the several most common websites used in this interpretation.

Автор: Herman E. Wyandt; Golder N. Wilson; Vijay S. Tonk
Название: Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis
ISBN: 9811097704 ISBN-13(EAN): 9789811097706
Издательство: Springer
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Описание: This new edition now titled “Human Chromosome Variation: Heteromorphism, Polymorphism and Pathogenesis” provides the reader with an up-to-date overview of microarrays, fragile sites, copy number variations and whole genome sequencing. Greatly expanding the discussion of microarray analysis in the previous edition of the book, are new chapters on microarray and genomic analysis, plus comprehensive tables on the subtle microdeletions and microduplications that are found on each chromosome, including 235 recurring copy number variants that are associated with well-established or emerging chromosomal syndromes. The current edition features concise information on cytogenetic methods and applications, extending these discussions to DNA analysis and genome sequencing. Sections on euchromatin, heterochromatin, FISH pattern, fragile site, copy number, and DNA sequence variation are integrated with actual clinical examples from cytogenetic laboratories and from clinical practice. The principles that allow for the distinction between benign chromosome / DNA variation and pathogenic heteromorphisms / polymorphisms are discussed and include references to the latest organizational guidelines and genomic or population databases. The two previous incarnations of this book: the ‘Atlas of Human Chromosome Heteromorphism’, and ‘Human Chromosome Variation: Heteromorphism and Polymorphism’ have been standard reference works in most cytogenetic laboratories, used by laboratory directors and clinicians all around the world. While widely used sections from the previous edition on cytogenetic technologies and heteromorphisms are retained intact the present volume adds extensive material on copy number variations (polymorphisms detected by microarray analysis), fragile sites in disease and cancer, and practical views on interpreting emerging technologies, including whole exome sequencing. This book should be of interest to clinicians, technicians and students who are or will be exposed to DNA and/or chromosome analysis and the data derived from these continuously developing techniques. This fully updated book volume will bring the reader up to speed on the latest technologies, their applications, benefits and drawbacks and as such, is a must read for anyone with an interest in DNA and chromosome analysis and the distinction between benign variation and pathogenic mistakes.

Автор: Gardner, R.j. Mckinlay (adjunct Professor, Clinica
Название: Gardner and Sutherland`s chromosome abnormalities and genetic counseling
ISBN: 0199329001 ISBN-13(EAN): 9780199329007
Издательство: Oxford Academ
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Описание: Even as classic cytogenetics has given way to molecular karyotyping, and as new deletion and duplication syndromes are identified almost every day, the fundamental role of the genetics clinic remains mostly unchanged. Genetic counselors and medical geneticists explain the "unexplainable,"
helping families understand why abnormalities occur and whether they're likely to occur again.

Chromosome Abnormalities and Genetic Counseling is the genetics professional's definitive guide to navigating both chromosome disorders and the clinical questions of the families they impact. Combining a primer on these disorders with the most current approach to their best clinical approaches, this
classic text is more than just a reference; it is a guide to how to think about these disorders, even as our technical understanding of them continues to evolve.

Completely updated and still infused with the warmth and voice that have made it essential reading for professionals across medical genetics, this edition of Chromosome Abnormalities and Genetic Counseling represents a leap forward in clinical understanding and communication. It is, as ever,
essential reading for the field.

Автор: Sameer Aga Syed, Banday Mujeeb Zafar, Nissar Saniya
Название: Genetic Polymorphism and Cancer Susceptibility
ISBN: 9813366982 ISBN-13(EAN): 9789813366985
Издательство: Springer
Цена: 139750.00 T
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Описание: This book discusses the role of genetic polymorphism in susceptibility to cancers.

Автор: W.D. Hamilton; J.C. Howard
Название: Infection, Polymorphism and Evolution
ISBN: 9401065233 ISBN-13(EAN): 9789401065238
Издательство: Springer
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Описание: Resulting from a Royal Society discussion meeting, this volume presents a short review of the topic of parasite-host co-evolution. Current thinking on evolution in parasites, viruses and other pathogens is discussed.

Автор: Sameer Aga Syed, Banday Mujeeb Zafar, Nissar Saniya
Название: Genetic Polymorphism and cancer susceptibility
ISBN: 9813367016 ISBN-13(EAN): 9789813367012
Издательство: Springer
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Описание: This book discusses the role of genetic polymorphism in susceptibility to cancers.

Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra
Название: Post-genomic Approaches in Cancer and Nano Medicine
ISBN: 8793102860 ISBN-13(EAN): 9788793102866
Издательство: Taylor&Francis
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Цена: 88800.00 T
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Описание: Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. Seen in several cancers is a substantial proportion of human genes showing alternative splicing and mis-regulation of Pre-mRNA splicing.

Post-genomic Approaches in Cancer and Nano Medicine further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection, and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving toward revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs.

Technical topics discussed in the book include:
- Alternative splicing and cancer
- Cancer imaging
- Nanomaterials in infectious diseases
- Nanomedicine in oxidative stress and cancer
- Nanoparticle based drug delivery systems

Автор: Henry F. Epstein
Название: Genetic Analysis of the X Chromosome
ISBN: 1468443488 ISBN-13(EAN): 9781468443486
Издательство: Springer
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Описание: The present volume contains the edited transcript of a collo- quium sponsored by the Muscular Dystrophy Association and held at Mountain Shadows Inn, Scottsdale, Arizona, December 14-16, 1981.

Автор: Baldev K. Vig
Название: Chromosome Segregation and Aneuploidy
ISBN: 3642849407 ISBN-13(EAN): 9783642849404
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of the NATO Advanced Research Workshop on Chromosome Segregation and Aneuploidy, held at Aghia Pelagia, Greece, October 10-15, 1992

Автор: Wyandt Herman E., Tonk Vijay S.
Название: Atlas of Human Chromosome Heteromorphisms
ISBN: 1402013035 ISBN-13(EAN): 9781402013034
Издательство: Springer
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Цена: 214280.00 T
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Описание: Critical to the accurate diagnosis of human illness is the need to distinguish clinical features that fall within the normal range from those that do not.

Автор: Gyula Hadlaczky
Название: Mammalian Chromosome Engineering
ISBN: 1493957759 ISBN-13(EAN): 9781493957750
Издательство: Springer
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Цена: 111790.00 T
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Описание: The rapid progression of genetics and molecular biology has turned chromosomal engineering from science fiction to reality, with the successful production of transgenic animals with engineered chromosomes and chromosomes developed for pharmaceutical protein production which are now ready for the medical industry.