This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Patil Popat M Название: Discoveries In Pharmacological Sciences ISBN: 9814355070 ISBN-13(EAN): 9789814355070 Издательство: World Scientific Publishing Рейтинг: Цена: 184800.00 T Наличие на складе: Есть Описание: Throughout history, the perpetuation of species, the need for survival, and human curiosity, intelligence and skills provided the basis for the development of drug science. This title contains the history of herbal medicine as it emerged about 5,000 years ago.
Автор: A. Claudio Cuello; Brian Collier Название: Pharmacological Sciences: Perspectives for Research and Therapy in the Late 1990s ISBN: 3034872208 ISBN-13(EAN): 9783034872201 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume arose from the scientific program of the XIIth International Congress of Pharmacology, held in Montreal, Canada, July 24-29, 1994. The objective that we pursued was to produce a volume of reasonable size which would feature all of the plenary lectures and symposia from those authors who agreed to participate.
Автор: Cho Название: Evidence-based Non-pharmacological Therapies for Palliative Cancer Care ISBN: 9400758324 ISBN-13(EAN): 9789400758322 Издательство: Springer Рейтинг: Цена: 177010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents the research evidence relevant to the application of a range of commonly used non-pharmacological interventions in supportive cancer care, including massage, acupressure, Qigong, yoga, mind-body therapy, and mindfulness-based intervention.
Автор: Mehrsheed Sinaki; Michael Pfeifer Название: Non-Pharmacological Management of Osteoporosis ISBN: 3319852973 ISBN-13(EAN): 9783319852973 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Невозможна поставка. Описание: This practical guide presents the most up-to-date information on the application of non-pharmacological and physical therapeutic measures, either used independently or in combination with pharmacotherapy, for the management of osteoporosis. Pharmacotherapy remains the primary treatment for osteoporosis, but to improve the biomechanical competence of bone and improve quality of life, there needs to be more comprehensive management approach involving non-pharmacological methods. The book opens with a discussion of the diagnosis, pathophysiology, complications and consequences of osteoporosis. Exercise, nutrition, orthotics, and other rehabilitation measures such as whole body vibration and electrical muscle stimulation, each described in details in chapters of their own, have had a beneficial impact on fall and fracture prevention as well as recovery post-fracture. In addition, the application of acupuncture for pain management and movement-based mind-body therapies like tai chi and the Feldenkrais method are explored.
Providing a description of independent and adjuvant techniques and practices for treatment and improving quality of life, Non-Pharmacological Management of Osteoporosis is an excellent resource for endocrinologists, bone specialists, physical therapists, occupational therapists and all clinical practitioners and staff working with osteoporosis patients.
Автор: Ninot, Gregory Название: Non-pharmacological interventions ISBN: 3030609707 ISBN-13(EAN): 9783030609702 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An Essential Answer to Current Demographic Health and Environmental Transitions.
Автор: William C.S. Cho Название: Evidence-based Non-pharmacological Therapies for Palliative Cancer Care ISBN: 9401785252 ISBN-13(EAN): 9789401785259 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Cancer is one of the leading killers in the world and the incidence is increasing, but most cancer patients and cancer survivors suffer much from the disease and its conventional treatments’ side effects. In the past, clinical data showed that some complementary and alternative medicine (CAM) possessed anticancer abilities, but some clinicians and scientists have queried about the scientific validity of CAM due to the lack of scientific evidence. There is great demand in the knowledge gap to explore the scientific and evidence-based knowledge of CAM in the anticancer field. With this aim, a book series is needed to structurally deliver the knowledge to readers. Integrative therapies comprise a variety of non-pharmacological interventions that assist in alleviating physical and psychological symptoms. Apart from being a life-threatening disease, cancer and its therapy are usually associated with a significant deterioration in the quality of life. There is growing evidence that non-pharmacological therapies provide symptom and pain management in cancer palliation. This volume is a specialised book presenting the research evidence relevant to the application of a range of commonly used non-pharmacological interventions in supportive cancer care, including massage, acupressure, Qigong, yoga, mind-body therapy, mindfulness-based intervention, and aromatherapy. A number of scientific researches and clinical studies support that these therapies offer potential beneficial effects for cancer patients in terms of reducing pain, anxiety, and other symptoms. Indeed, non-pharmacological therapies are increasingly gaining acceptance in the healthcare community as complementary to conventional cancer treatments. Most of them are non-invasive, inexpensive, and useful in improving quality of life, and they may be accessed by patients themselves.
Название: Integrating Psychological and Pharmacological Treatments for Addictive Disorders ISBN: 1138919098 ISBN-13(EAN): 9781138919099 Издательство: Taylor&Francis Рейтинг: Цена: 168430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Integrating Psychological and Pharmacological Treatments for Addictive Disorders distills the complex literature on addiction, offering a curated toolbox of integrated pharmacological and psychotherapeutic treatments in chapters authored by leading experts.
Автор: Pugazhenthan Thangaraju Название: A Pharmacological Guide to Non-Steroidal Anti-Inflammatory Medications ISBN: 1536198366 ISBN-13(EAN): 9781536198362 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: The purpose of this book is to provide a comprehensive source of information regarding NSAIDs in detail. NSAIDs are widely used and prescribed to all age groups. This book represents a new approach for undergraduate and post-graduate medical students of all specialties. The book was written in simple and easily understandable language for everyone. This book is mainly focused on NSAIDs and related topics like mechanism and pharmacological actions, adverse drug reactions, fixed dose combinations, poisoning of overdose, usage in neurological conditions, geriatrics, paediatrics and pregnancy, NSAID-induced gastropathy and nephropathy, NSAIDs in oncology, pharmacogenomics, and in COVID. Their use is associated with a vast spectrum of adverse drug effects, so drug selection is crucial in various conditions. Each chapter of the book presents the pharmacology of NSAIDs in the framework of biochemical, physiologic or pathophysiological systems. Each topic provides an understanding of the basic concepts of NSAIDs on already existing and on newer drugs and their pharmacological use in various organ systems at different age groups. Updated and recent information including the use of NSAIDs in COVID has been added. Detailed drug information in aspects of drug selection and its contraindications as per patients disease status and updated approaches in newer clinical perspectives were included. Diagrams, tables, and flowcharts are included to make the concepts easier to understand. At the end of each chapter, useful references are added for further reading.
Название: Integrating psychological and pharmacological treatments for addictive disorders ISBN: 1138919101 ISBN-13(EAN): 9781138919105 Издательство: Taylor&Francis Рейтинг: Цена: 37760.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Integrating Psychological and Pharmacological Treatments for Addictive Disorders distills the complex literature on addiction, offering a curated toolbox of integrated pharmacological and psychotherapeutic treatments in chapters authored by leading experts.
Автор: R. E. Beamish; V. Panagia; Naranjan S. Dhalla Название: Pharmacological Aspects of Heart Disease ISBN: 1461292220 ISBN-13(EAN): 9781461292227 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of an International Symposium on Heart Metabolism in Health and Disease and the 3rd Annual Cardiology Symposium of the University of Manitoba July 8-11, 1986, Winnipeg, Canada
Автор: R. E. Beamish; V. Panagia; Naranjan S. Dhalla Название: Pharmacological Aspects of Heart Disease ISBN: 0898388678 ISBN-13(EAN): 9780898388671 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of an International Symposium on Heart Metabolism in Health and Disease and the 3rd Annual Cardiology Symposium of the University of Manitoba July 8-11, 1986, Winnipeg, Canada
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