Epigenetics in Allergy and Autoimmunity, Chang Christopher, Lu Qianjin

Автор: Chang Christopher, Lu Qianjin
Название: Epigenetics in Allergy and Autoimmunity
ISBN: 9811534489 ISBN-13(EAN): 9789811534485
Издательство: Springer
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Цена: 139750.00 T
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Описание: The book is divided into three parts - the first is an introduction to epigenetics and the methods that have been developed to study epigenetics, the second addresses epigenetics in allergic diseases and the third part will cover epigenetics in autoimmune diseases.

Автор: Tollefsbol, Trygve
Название: The Epigenetics of Autoimmunity
ISBN: 0128099127 ISBN-13(EAN): 9780128099124
Издательство: Elsevier Science
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Цена: 159450.00 T
Наличие на складе: Нет в наличии.
Описание: The Epigenetics of Autoimmunity covers a topic directly related to translational epigenetics. Via epigenetic mechanisms, a number of internal and external environmental risk factors, including smoking, nutrition, viral infection and the exposure to chemicals, could exert their influence on the pathogenesis of autoimmune diseases. Such factors could impact the epigenetic mechanisms, which, in turn, build relationship with the regulation of gene expression, and eventually triggering immunologic events that result in instability of immune system. Since epigenetic aberrations are known to play a key role in a long list of human diseases, the translational significance of autoimmunity epigenetics is very high. . To bridge the gap between environmental and genetic factors, over the past few years, great progress has been made in identifying detailed epigenetic mechanisms for autoimmune diseases. Furthermore, with rapid advances in technological development, high-throughput screening approaches and other novel technologies support the systematic investigations and facilitate the epigenetic identification. This book covers autoimmunity epigenetics from a disease-oriented perspective and several chapters are presented that provide advances in wide-spread disorders or diseases such as systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), multiple sclerosis (MS), type 1 diabetes (T1DM), systemic sclerosis (SSc), primary Sj?gren's syndrome (pSS) and autoimmune thyroid diseases (AITDs). . These emerging epigenetic studies provide new insights into autoimmune diseases, raising great expectations among researchers and clinicians. This seminal book on this topic comprehensively covers the most recent advances in this exciting and rapidly developing new science. They might reveal not only new clinical biomarkers for diagnosis and disease progression, but also novel targets for potential epigenetic therapeutic treatment.

Автор: Pawankar
Название: Allergy Frontiers:Epigenetics, Allergens and Risk Factors
ISBN: 4431998233 ISBN-13(EAN): 9784431998235
Издательство: Springer
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Цена: 191550.00 T
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Описание: When I entered the field of allergy in the early 1970s, the standard textbook was a few hundred pages, and the specialty was so compact that texts were often authored entirely by a single individual and were never larger than one volume.

Автор: Andreas Radbruch; Peter E. Lipsky
Название: Current Concepts in Autoimmunity and Chronic Inflammation
ISBN: 364206745X ISBN-13(EAN): 9783642067457
Издательство: Springer
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Цена: 213360.00 T
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Описание: In addition, there are in?uences that are extrinsic to potentially auto-reactive lymphocytes, including the function of regulatory cells, d- ferentiation state of antigen-presenting cells, availability of self-antigen, the cytokine and chemokine milieu, as well as the traf?cking patterns involved in generating productive immune interactions.

Автор: Andras Perl (Editor)
Название: Autoimmunity: Methods and Protocols (Methods in Molecular Biology)
ISBN: 1607617196 ISBN-13(EAN): 9781607617198
Издательство: Springer
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Цена: 135090.00 T
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Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.

Автор: Smith Kendall A
Название: Quantal Theory Of Immunity, The: The Molecular Basis Of Autoimmunity And Leukemia
ISBN: 9814271756 ISBN-13(EAN): 9789814271752
Издательство: World Scientific Publishing
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Цена: 85530.00 T
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Описание: Explains how immune system functions, namely, how individual cells of the immune system make the decision to respond or not to respond to foreign microbes and molecules, and how the critical molecules function to trigger the cellular reactions in an all-or-none manner. This book also explains why vaccines fail.

Автор: Nathanson
Название: Viral Pathogenesis and Autoimmunity.2002
ISBN: 0781711037 ISBN-13(EAN): 9780781711036
Издательство: Lippincott Williams & Wilkins
Цена: 54910.00 T
Наличие на складе: Нет в наличии.
Описание: Written by eminent authorities on viral pathogenesis and immunity, this text provides a coherent, concise introduction to the field. The authors focus on fundamental principles and present a well-organized overview that is easy for readers to absorb.Section 1, essentials of viral pathogenesis , describes the sequential events in viral infection, the localization of viral infections, and the variety of virus-cell interactions.Section 2, host responses to viral infection , examines immune responses, including virus-induced immunopathology and immunosuppression.Section 3, virus-host interactions , covers virulence, viral persistence, virus-induced oncogenesis, and host susceptibility.Section 4, prevention of viral infections , explains the key principles of vaccine development.

Автор: Yehuda Shoenfeld,Nancy Agmon–Levin
Название: Vaccines and Autoimmunity
ISBN: 1118663438 ISBN-13(EAN): 9781118663431
Издательство: Wiley
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Цена: 149900.00 T
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Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.

Автор: Val?rie Quesniaux; Bernhard Ryffel; Franco Di Pado
Название: IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
ISBN: 3034805217 ISBN-13(EAN): 9783034805216
Издательство: Springer
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Цена: 174150.00 T
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Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.

Автор: Andras Perl
Название: Autoimmunity
ISBN: 149395637X ISBN-13(EAN): 9781493956371
Издательство: Springer
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Цена: 135090.00 T
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Описание: Continued refinement of wide-spread access to transgenic technology has allowed for new animal models have been developed that exhibit features of autoimmune disease have been developed that exhibit features of autoimmune disease.

Автор: Val?rie Quesniaux; Bernhard Ryffel; Franco Di Pado
Название: IL-17, IL-22 and Their Producing Cells: Role in Inflammation and Autoimmunity
ISBN: 3034807732 ISBN-13(EAN): 9783034807739
Издательство: Springer
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Цена: 156720.00 T
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Описание: In a fully revised second edition, this comprehensive review of clinical and experimental aspects of IL-17 and IL-22 and the cells that produce them covers the latest scientific advances, with additional chapters on processes such as receptor family signaling.

Автор: Moncef Zouali
Название: Molecular Autoimmunity
ISBN: 1461498945 ISBN-13(EAN): 9781461498940
Издательство: Springer
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Цена: 186330.00 T
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Описание: - Preface -Contributors -Innate Immunity in Experimental Autoimmune Myocarditis -Toll-Like Receptor 9 and Autoimmunity -C-Reactive Protein as a Regulator of Autoimmune Disease -NKT Cells and Autoimmune Type 1 Diabetes -The Genetics of Human Autoimmune Diseases -Failure to Maintain T cell DNA Methylation and Chromatin Structure Contributes to Human Lupus -Complement Components C4A and C4B in Human Lupus -Non-MHC Genetic Polymorphisms with Functional Importance for Human Myasthenia Gravis -Rheumatic Heart Disease: Molecular Basis of Autoimmune Reactions Leading to Valvular Lesions -Autoimmunity Against Desmogleins in Pemphigus Vulgaris -The Molecular Basis of Celiac Disease -Intrathymic Expression of Neuromuscular Acetylcholine Receptors and the Immunopathogenesis of Myasthenia Gravis -Autoantiboties and Nephritis: Different Roads May Lead to Rome -Estrogen, Interferon-gamma, and Lupus -Extent of Regulatory T cell Influence on Major Histocompatibility Complex Class II Gene Control of Susceptibility in Murine Autoimmune Thyroiditis -The Role of Autoimmunity in Multiple Sclerosis -Crippled B Lymphocyte Signaling Checkpoints in Systemic Autoimmunity -Disrupted T cell Receptor Signaling Pathways in Systemic Autoimmunity -Immune cell Signaling and Gene Transcription in Human Systemic Lupus Erythematosus -Accumulation of Self-Antigens in Systemic Lupus Erythematosus -B Lymphocyte Depletion Therapy in Autoimmune Disorders: Chasing Trojan Horse? -B Lymphocyte Stimulator (BLyS) and Autoimmune Rheumatic Diseases -Control and Induction of Autoimmunity by Cytokine and Anti-Cytokine Treatments -Hematopoietic Stem Cell Transplantation for the Treatment of Severe Autoimmune Diseases -Molecular Mimicry in Autoimmune Uveitis: From Pathogenesis to Therapy -Molecular Pathogenesis of the Antiphospholipid Syndrome: Towards Novel Therapeutic Targets -A Novel Approach to the Prevention of Atherosclerosis -Antigen-SpecificRegulation of Autoimmunity -Index