Автор: Maria M.Mota; Ana Rodriguez Название: Malaria ISBN: 3319832395 ISBN-13(EAN): 9783319832395 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Currently, malaria kills more than 300,000 people per year, making it a top priority of world leaders and international organizations, who are working towards implementing and coordinating efforts to eradicate this disease. An effective malaria vaccine is recognized as the key element that will decide between success and failure in this fight. At present, despite intensive research efforts, such a vaccine is not yet available for use.
However, there are a number of advanced candidate vaccines with high chances of success in the short term. Malaria: Immune Response to Infection and Vaccination provides a comprehensive view on the immune response to malaria and to the different vaccines under development. The book offers the following:- Contributions by top research leaders in the field,- Comparisons of the immune responses to both malaria infection and malaria vaccines, which are traditionally treated separately, - Coverage of the immune responses to the different stages of malaria, which are frequently treated as separate fields of research.
Автор: Szlez?k Название: The Making of Global Health Governance ISBN: 1137020822 ISBN-13(EAN): 9781137020826 Издательство: Springer Рейтинг: Цена: 83850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A study of governance in the emerging global domain, this book traces the evolution of global public policy making by focusing on four entities: a globalizing sector (health); a global disease (HIV/AIDS); a global organization (the Global Fund); and a major sovereign state (China).
Автор: Sherman Irwin W Название: Malaria Vaccines: The Continuing Quest ISBN: 1786340046 ISBN-13(EAN): 9781786340047 Издательство: World Scientific Publishing Рейтинг: Цена: 116160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
In 2013, 200 million people were infected with malaria, resulting in over 584,000 deaths, with the potential to affect over half the world's population. Such is the widespread nature of malaria that it is increasingly believed only a vaccine will lead to its eradication.
Although the first attempt at a vaccine was made a century ago, it is only in the last 30 years that real progress in testing has been made, in the hope of discovering a molecule that can provide long-lasting protection against the disease. In July 2015, GlaxoSmithKline (GSK) announced that after 30 years of research it had received the green light from the European Medicines Agency for the world's first malaria vaccine, RTS, S, for use in African children aged 6 weeks to 17 months.
This book chronicles the development of RTS, S -- done in collaboration with the Walter Reed Army Institute for Research, the PATH Malaria Vaccine Initiative (MVI) and funded in part by the Bill and Melinda Gates Foundation -- as well as previous candidate vaccines. It also focusses on the continuing quest to find more effective vaccines against this continuing health crisis. Finally, it provides an easily understood background on recombinant DNA and monoclonal antibodies and places them in perspective to their contributions to malaria vaccine development.
This book serves as a convenient and easily accessible source of information for students, teachers, microbiologists, parasitologists, physicians, clinicians and research funders.
Автор: Addmore Shonhai; Gregory L. Blatch Название: Heat Shock Proteins of Malaria ISBN: 9402402594 ISBN-13(EAN): 9789402402599 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes the role of heat shock proteins in the life cycle of malaria parasites. It examines the role of heat shock protein families from Plasmodium falciparum, their role in protein folding and in the development of malaria pathology.
Автор: S. M. Niaz Arifin,Gregory R. Madey,Frank H. Collin Название: Spatial Agent–Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology ISBN: 1118964357 ISBN-13(EAN): 9781118964354 Издательство: Wiley Рейтинг: Цена: 113990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Presents an overview of the complex biological systems used within a global public health setting and features a focus on malaria analysis Bridging the gap between agent–based modeling and simulation (ABMS) and geographic information systems (GIS), Spatial Agent–Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology provides a useful introduction to the development of agent–based models (ABMs) by following a conceptual and biological core model of Anopheles gambiae for malaria epidemiology. Using spatial ABMs, the book includes mosquito (vector) control interventions and GIS as two example applications of ABMs, as well as a brief description of epidemiology modeling. In addition, the authors discuss how to most effectively integrate spatial ABMs with a GIS. The book concludes with a combination of knowledge from entomological, epidemiological, simulation–based, and geo–spatial domains in order to identify and analyze relationships between various transmission variables of the disease. Spatial Agent–Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology also features: Location–specific mosquito abundance maps that play an important role in malaria control activities by guiding future resource allocation for malaria control and identifying hotspots for further investigation Discussions on the best modeling practices in an effort to achieve improved efficacy, cost–effectiveness, ecological soundness, and sustainability of vector control for malaria An overview of the various ABMs, GIS, and spatial statistical methods used in entomological and epidemiological studies, as well as the model malaria study A companion website with computer source code and flowcharts of the spatial ABM and a landscape generator tool that can simulate landscapes with varying spatial heterogeneity of different types of resources including aquatic habitats and houses Spatial Agent–Based Simulation Modeling in Public Health: Design, Implementation, and Applications for Malaria Epidemiology is an excellent reference for professionals such as modeling and simulation experts, GIS experts, spatial analysts, mathematicians, statisticians, epidemiologists, health policy makers, as well as researchers and scientists who use, manage, or analyze infectious disease data and/or infectious disease–related projects. The book is also ideal for graduate–level courses in modeling and simulation, bioinformatics, biostatistics, public health and policy, and epidemiology. S. M. Niaz Arifin, PhD, is Research Assistant Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, and American Society of Tropical Medicine and Hygiene, and the recipient of The American Society of Tropical Medicine and Hygiene Travel Award in 2011, his research interests include agent–based modeling and simulation, public health, data warehousing, and geographic information systems. Gregory R. Madey, PhD, is Research Professor in the Department of Computer Science and Engineering at the University of Notre Dame. A member of The Society for Computer Simulation, Institute of Electrical and Electronics Engineers Computer Society, and American Society of Tropical Medicine and Hygiene, his research interests include agent–based modeling and simulation, cyberinfrastructure, bioinformatics, biocomplexity, e–Technologies, open source software, disaster management, and health informatics. Frank H. Collins, PhD, is Professor in the Department of Biological Sciences at the University of Notre Dame. His research interests include genome level studies of arthropod vectors of human pathogens, the biology of malaria vectors with a focus on the development of molecular tools that will permit better resolution of questions about vector population ec
Автор: Cueto Marcos Название: Cold War, Deadly Fevers: Malaria Eradication in Mexico, 1955-1975 ISBN: 1421415569 ISBN-13(EAN): 9781421415567 Издательство: Неизвестно Рейтинг: Цена: 46590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Following the story through the dwindling campaign in the late 1960s and early 1970s, Cueto raises questions relevant to today`s international health campaigns against malaria, AIDS, and tuberculosis.
Автор: Susann Roth, Jane Parry Название: Regional Malaria and Other Communicable Disease Threats Trust Fund: Final Report ISBN: 9292613642 ISBN-13(EAN): 9789292613648 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 19230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Details the key achievements of the Regional Malaria and Other Communicable Disease Threats Trust Fund from its creation in 2013 to the first half of 2018. The report provides detailed analysis of the results by outcome, profiles specific projects that serve as exemplars of the fund`s impact, and offers insights managing similar trust funds.
Автор: Wahlgren, Mats Название: Malaria ISBN: 9057024462 ISBN-13(EAN): 9789057024467 Издательство: Taylor&Francis Рейтинг: Цена: 224570.00 T Наличие на складе: Нет в наличии.
Автор: Stoute Название: Complement Activation in Malaria Immunity and Pathogenesis ISBN: 3319772570 ISBN-13(EAN): 9783319772578 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Plasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite.
Автор: Sekalala Название: Soft Law and Global Health Problems: Lessons from Responses to HIV/AIDS, Malaria and Tuberculosis ISBN: 1107049520 ISBN-13(EAN): 9781107049529 Издательство: Cambridge Academ Рейтинг: Цена: 105600.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is for legal, development, policy and health scholars who are interested in global health law. It examines key global health governance questions on how the international community can create access to essential medicines for the millions of people who are suffering from AIDS, tuberculosis and malaria.
Автор: Henry M. Staines; Sanjeev Krishna Название: Treatment and Prevention of Malaria ISBN: 3034808089 ISBN-13(EAN): 9783034808088 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs.
Автор: Nicole A. Szlez?k Название: The Making of Global Health Governance ISBN: 1349437557 ISBN-13(EAN): 9781349437559 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A study of governance in the emerging global domain, this book traces the evolution of global public policy making by focusing on four entities: a globalizing sector (health); a global disease (HIV/AIDS); a global organization (the Global Fund); and a major sovereign state (China).
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