RNA Interference and Cancer Therapy, Lekha Dinesh Kumar
Автор: Karp Daniel D Название: Handbook of Targeted Cancer Therapy and Immunotherapy ISBN: 1496389131 ISBN-13(EAN): 9781496389138 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 53190.00 T Наличие на складе: Поставка под заказ. Описание: A must-have resource for oncologists, researchers, and other cancer care professionals! This comprehensive yet concise reference includes clinical trial results of more than 190 targeted therapy and immunotherapy agents. Immunotherapy trial results expanded Tumor immunology section added Recent landmark trial results incorporated FDA approvals highlighted Approach clinical challenges from any direction. Chapters organized by tumor type, pathway, and drug name. Find information quickly and easily, using a color-coded, intuitive format. Small enough to fit in your lab coat pocket. Or, download the eBook to your smartphone or other device for even more convenient referencing. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Автор: Grumezescu, Alexandru Mih Название: Nanostructures for Cancer Therapy ISBN: 0323461441 ISBN-13(EAN): 9780323461443 Издательство: Elsevier Science Рейтинг: Цена: 151590.00 T Наличие на складе: Поставка под заказ. Описание:
Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics.
In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents.
The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer.
Автор: Peter M. Schlag; M.M. Eggermont; Ulrike S. Stein Название: Regional Cancer Therapy ISBN: 1617377112 ISBN-13(EAN): 9781617377112 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume provides a biological and pharmacological background for regional cancer therapy, strategies and techniques for regional therapies, and specific indications and results for different tumor entities.
Автор: Peter Bannasch Название: Cancer Therapy ISBN: 3540510346 ISBN-13(EAN): 9783540510345 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Benjamin Bonavida Название: Nitric Oxide and Cancer: Pathogenesis and Therapy ISBN: 3319136100 ISBN-13(EAN): 9783319136103 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Advances in Nitric Oxide and Cancer is a volume that serves to give the latest research on nitric oxide (NO) and cancer. More specifically, the volume reviews significant advances in the application of NO-mediated drugs. The volume explores nitric oxide and its relationship to cancer spanning from its roles in the pathogenesis, prognosis, gene and protein modifications, regulation of resistance to cytotoxics, and therapeutic applications. With chapters written by leading experts, the volume addresses the burgeoning interest in a rapidly advancing field and provides a valuable resource to scientists who have initiated research as well as clinical investigations in their laboratories on the various roles of NO and cancer.
Автор: W.B. Peeling; Hermann Becker Название: Progress in Diagnostics and Therapy of Prostatic Cancer ISBN: 3540601953 ISBN-13(EAN): 9783540601951 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: There is now increasing awareness by the general public in European countries that prostate cancer is a serious threat to health, and this has created higher expectations for improved and more effective methods for detecting and treating the disease.
Автор: Marcelo G. Kazanietz Название: Protein Kinase C in Cancer Signaling and Therapy ISBN: 1617796913 ISBN-13(EAN): 9781617796913 Издательство: Springer Рейтинг: Цена: 278580.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Protein kinase C (PKC), a family of serine-threonine kinases, rocketed to the forefront of the cancer research field in the early 1980`s with its identification as an effector of phorbol esters, natural products with tumor promoting activity.
Автор: Peter Jordan Название: Targeted Therapy of Colorectal Cancer Subtypes ISBN: 3030027708 ISBN-13(EAN): 9783030027704 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: Colorectal cancer (CRC) is a leading cause of cancer-related death worldwide. Recent years have increased significantly our understanding of the genetic alterations that can underlie CRC, but also unraveled the molecular heterogeneity of the disease. Although a simple correlation between genetic pathways, histopathological features and clinical outcome cannot be established, the heterogeneity of CRC is also an opportunity for the development of targeted therapeutic approaches, able to treat an individual tumor with higher efficiency and less toxic side effects. One CRC subtype is characterized by high mutation rates (MSI-H), DNA methylation changes (CIMP-H), mutation in the BRAF oncogene and occurrence of serrated adenomas in the proximal colon. Other groups prevail in the distal colon and consist of either adenomatous polyps with chromosomal aberrations (CIN) and WNT pathway activation, or carry frequent KRAS mutation and metabolic deregulation, or have strong mesenchymal and infiltrative characteristics. Characterization of driver-mutation events in these CRC subgroups has led to the development of specific drugs targeting, for example, the MAPK pathway, but initial clinical trials have revealed unexpected response rates. The collection of chapters in this volume address the biology of specific CRC subtypes and how these may be targeted to improve precision therapy and clinical benefit for the patients.
Автор: Scott Q. Harper Название: RNA Interference Techniques ISBN: 1493957627 ISBN-13(EAN): 9781493957620 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents methods for design and delivery of artificial inhibitory RNAs to neural tissue and for detecting or cloning endogenous microRNAs, used in research and in development of therapeutics for dominant genetic disorders, cancer, or viral infection.
Автор: Lekha Dinesh Kumar Название: RNA Interference and Cancer Therapy ISBN: 1493992198 ISBN-13(EAN): 9781493992195 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Поставка под заказ. Описание: This comprehensive volume collects a repertoire of techniques for the adoption and exploitation of RNA interference (RNAi) as a fertile strategy to develop the bio-drugs of future in the vital field of cancer research. Exploring the immense ‘bench to bedside’ potential of RNAi as a therapeutic molecule, the book focuses many of its chapters on nanoparticle-based targeted deliveries, including aptamers, as well as techniques for using RNAi technology to combat various cancers in preclinical studies. Each of the 26 chapters is authored by the pioneers in the respective areas and thus provides a practical and empirical account of the techniques that could be used as benchmark tools in the area of cancer research. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and essential, RNA Interference and Cancer Therapy: Methods and Protocols provides the necessary guidance for both novice and professional researchers who intend to discover and innovate newer means of using RNAi technology to combat cancer, one of the greatest scourges of human health.
Автор: Mouldy Sioud Название: RNA Interference ISBN: 1493948911 ISBN-13(EAN): 9781493948918 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: RNA Interference: Challenges and Therapeutic Opportunities provides readers with recent advances in siRNA design, delivery, targeting and methods to minimize siRNA`s unwanted effects.
Автор: Patrick J. Paddison; Peter K. Vogt Название: RNA Interference ISBN: 3642444458 ISBN-13(EAN): 9783642444456 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In the last few years the major effect that RNAi has had in invertebrate systems like C.elegans and drosophila is beginning to take hold in mammalian systems through both single gene knockdown experiments and genome-scale screens. In the next decade, there will no doubt be both notable successes and failures as we attempt to apply this genetic tool to various biological problems for the first time in academia and industry. Through the introduction of RNAi, mammalian systems have finally gained admittance to the pantheon of model genetic systems.
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