Multi-Parametric Live Cell Microscopy of 3D Tissue Models, Ruslan I. Dmitriev
Автор: Ruslan I. Dmitriev Название: Multi-Parametric Live Cell Microscopy of 3D Tissue Models ISBN: 3319673572 ISBN-13(EAN): 9783319673578 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A variety of applications are covered, including multi-parametric quantitative imaging in intestinal organoid culture, autofluorescence imaging in cancer and stem cell biology, Ca2+ imaging in neural ex vivo tissue models, as well as multi-parametric imaging of pH and viscosity in cancer biology.
This thesis describes novel substrate embedded physical sensors that can be used to monitor different types of cell-based assays non-invasively and label-free. The sensors described provide integrative information of the cells under study with an adaptable time resolution (ranging from milliseconds to days). This information about the dynamic cell response to chemical, physical or biological stimuli defines a new paradigm in fundamental biomedical research.
The author, Maximilian Oberleitner, describes approaches in which the cells are directly grown on different sensor surfaces (gold-film electrodes, shear wave resonators or dye-doped polymer films). This approach, with the reacting cells in particularly close proximity and contact with the sensor surface, is key to a remarkable sensitivity, opening the way for a variety of new applications. This thesis not only introduces the fundamentals of each approach, but it also describes in great detail the design
principles and elucidates the boundary conditions of the new sensors.
Автор: Maximilian Oberleitner Название: Label-free and Multi-parametric Monitoring of Cell-based Assays with Substrate-embedded Sensors ISBN: 3319453831 ISBN-13(EAN): 9783319453835 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Introduction.- Objectives.- Methods & Instrumentation.- MQCM: Multiple Cytomechanic Sensing.- QCM-ECIS: Combined Viscoelastic and Dielectric Sensing of Cells.- QCM-OCS: Optochemical Sensing of Temperature and pO2 in the Cell Surface Junction.- Summary.- Appendix.
Автор: Vladimir G. Baryshevsky; Ilya D. Feranchuk; Alexan Название: Parametric X-Ray Radiation in Crystals ISBN: 3642434215 ISBN-13(EAN): 9783642434211 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This radiation is generated by the motion of electrons inside a crystal, whereby the emitted photons are diffracted by the crystal and the radiation intensity critically depends on the parameters of the crystal structure.
Автор: Yar M. Mughal Название: A Parametric Framework for Modelling of Bioelectrical Signals ISBN: 9812879684 ISBN-13(EAN): 9789812879684 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals for experimenting with and evaluating the performance of e.g.
Автор: Mughal Yar M. Название: A Parametric Framework for Modelling of Bioelectrical Signals ISBN: 9811357358 ISBN-13(EAN): 9789811357350 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines non-invasive, electrical-based methods for disease diagnosis and assessment of heart function. In particular, a formalized signal model is proposed since this offers several advantages over methods that rely on measured data alone. By using a formalized representation, the parameters of the signal model can be easily manipulated and/or modified, thus providing mechanisms that allow researchers to reproduce and control such signals. In addition, having such a formalized signal model makes it possible to develop computer tools that can be used for manipulating and understanding how signal changes result from various heart conditions, as well as for generating input signals for experimenting with and evaluating the performance of e.g. signal extraction methods. The work focuses on bioelectrical information, particularly electrical bio-impedance (EBI). Once the EBI has been measured, the corresponding signals have to be modelled for analysis. This requires a structured approach in order to move from real measured data to the model of the corresponding signals. This book proposes a generic framework for this procedure. It can be used as a guide for modelling impedance cardiography (ICG) and impedance respirography (IRG) signals, as well as for developing the corresponding bio-impedance signal simulator (BISS).
Автор: August Bernd; J?rgen Bereiter-Hahn; Frank Hevert; Название: Cell and Tissue Culture Models in Dermatological Research ISBN: 3642778194 ISBN-13(EAN): 9783642778193 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this volume the impact of cell culture models ondermatological research is discussed by scientists frommedicine, physiology, biology, pharmacology,and pharmacy.
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