Immunotherapy of Hepatocellular Carcinoma, Tim F. Greten

Автор: Tim F. Greten
Название: Immunotherapy of Hepatocellular Carcinoma
ISBN: 3319649574 ISBN-13(EAN): 9783319649573
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Additionally, cell based therapies (adoptive T cell therapy, CAR T cells and TCR transduced T cells) have demonstrated significant efficacy in patients with B cell malignancies and melanoma.

Автор: R.J.A. van Moorselaar; Frans M.J. Debruyne; Ronald
Название: Immunotherapy of Renal Cell Carcinoma
ISBN: 3540528350 ISBN-13(EAN): 9783540528357
Издательство: Springer
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Цена: 102480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With contributions by numerous experts

Автор: Donnadieu
Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
ISBN: 3319422219 ISBN-13(EAN): 9783319422213
Издательство: Springer
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Цена: 139310.00 T
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Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.

Автор: Benjamin Bonavida; Salem Chouaib
Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy
ISBN: 3319178067 ISBN-13(EAN): 9783319178066
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.

Автор: Vadde Ramakrishna, Nagaraju Ganji Purnachandra
Название: Immunotherapy for Gastrointestinal Malignancies
ISBN: 9811564892 ISBN-13(EAN): 9789811564895
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers.

Автор: Vo-Dinh Tuan
Название: Nanoparticle-Mediated Immunotherapy
ISBN: 3030783375 ISBN-13(EAN): 9783030783372
Издательство: Springer
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Plasmonic nanoparticles are a special type of metallic nanoparticles that has received great interest due to their enhanced optical and electromagnetic properties and their superior capacity to convert photon energy into heat for selective photothermal therapy at the nanoscale level.

Автор: Vadde Ramakrishna, Nagaraju Ganji Purnachandra
Название: Immunotherapy for Gastrointestinal Malignancies
ISBN: 9811564868 ISBN-13(EAN): 9789811564864
Издательство: Springer
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers.

Автор: Howard L. Kaufman; Jedd D. Wolchok
Название: General Principles of Tumor Immunotherapy
ISBN: 9400787146 ISBN-13(EAN): 9789400787148
Издательство: Springer
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Цена: 156720.00 T
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Описание: This book brings together the world`s leading authorities on tumor immunology. The role of the innate and adaptive immune responses is discussed and the implications of these responses for the design of clinical strategies to combat cancer are illustrated.

Автор: Donnadieu Emmanuel
Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy
ISBN: 3319825283 ISBN-13(EAN): 9783319825281
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers.

Автор: Mototsugu Oya
Название: Renal Cell Carcinoma
ISBN: 4431566619 ISBN-13(EAN): 9784431566618
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Невозможна поставка.
Описание: This book provides a comprehensive review of diagnosis and treatments of renal cell carcinoma (RCC) for practitioners and researchers with an interest in this disease. A major aim of the book is to present the most important and most recent advances in molecular bases and targeted therapy for this neoplasm. The remarkable resistance to chemotherapy and radiotherapy and the minimum contribution of cancer genes that commonly mutate in other adult epithelial cancers have made RCC highly distinct from other types of solid neoplasms. In the past decade, however, treatment options for RCC have been expanding and moving quickly toward laboratory-based and molecular-targeted therapies. Advances in RCC therapy also have brought novel treatment options to other types of cancer, such as a TKI for hepatocellular carcinoma and gastrointestinal tumors, as well as mTOR inhibitors to progressive neuroendocrine tumors of pancreatic origin and to breast cancer, suggesting that RCC is no longer an 'orphan disease' in the field of molecular oncology. Additional topics covered in the book include pharmacokinetics and pharmacodynamics in molecular-targeted agents and the putative mechanism of resistance to anti-angiogenic agents, such as intratumoral heterogeneity or cancer stem cell population. This volume provides the latest and most useful information for all readers who are eagerly devoted to curing renal cell carcinoma.

Автор: Pierre Busson
Название: Nasopharyngeal Carcinoma
ISBN: 1493954954 ISBN-13(EAN): 9781493954957
Издательство: Springer
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Цена: 148010.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book takes a "translational medicine and biology" approach to Nasopharyngeal Carcinoma, developing knowledge from basic science towards diagnostic and therapeutic applications and reciprocally proposing new questions for basic scientists.