Actin Cytoskeleton in Cancer Progression and Metastasis - Part C, Galluzzi Lorenzo, Thomas Clement
Автор: Yaroslav B. Blume; W. Vance Baird; Alla I. Yemets; Название: The Plant Cytoskeleton: a Key Tool for Agro-Biotechnology ISBN: 1402088426 ISBN-13(EAN): 9781402088421 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The cytoskeleton is a key intracellular structure governing relevant processes such as cell division, growth, molecule trafficking, and response to internal and external signals. This work deals with the cytoskeleton as the `server` for these numerous and multi-tasked nodes. It presents achievements attained in basic research of the cytoskeleton.
Автор: Philippe Jeanteur Название: Cytoskeleton and Small G Proteins ISBN: 3540648089 ISBN-13(EAN): 9783540648086 Издательство: Springer Рейтинг: Цена: 241310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This work focuses on a family of cellular proteins which transmit signals in the form of small molecules outside the cell, the Rho Ras-like GTPases, and examines their role in normal cellular processes and development. Also discussed are their roles in cancer formation and microbial pathogenesis.
Автор: Galluzzi, Lorenzo Название: Actin Cytoskeleton In Cancer Progression And Metastasis - Part A,355 ISBN: 0128212810 ISBN-13(EAN): 9780128212813 Издательство: Elsevier Science Рейтинг: Цена: 196510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Actin Cytoskeleton in Cancer Progression and Metastasis Part A, Volume 355, in the International Review of Cell and Molecular Biology series provides an overview of the roles of the actin cytoskeleton and some of its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response.
Автор: Galluzzi, Lorenzo Название: Actin Cytoskeleton In Cancer Progression And Metastasis - Part B,356 ISBN: 0128212837 ISBN-13(EAN): 9780128212837 Издательство: Elsevier Science Рейтинг: Цена: 196510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Actin Cytoskeleton in Cancer Progression and Metastasis (Part B), Volume 356 in the International Review of Cell and Molecular Biology series, provides an overview on the roles of the actin cytoskeleton and its key structural regulators, including WASp, Paxillin, Myosin, Testin, L-Plastin and profilin, and in central processes underlying cancer progression and metastasis, such as changes in cell morphology and gene expression, acquisition of migratory and invasive capabilities, and evasion from the immune response. Specific chapters in this release cover Actin dynamics during tumor cell dissemination, Actin cytoskeleton remodeling during cancer cell migration, Cytoskeletal Mechanics Drives Heterogeneity in Epithelial Ovarian Cancer, and much more.
Автор: Abdel-Majid Khatib Название: The Proprotein Convertases: Discovery, Characteristics and Link to Tumor Progression, Angiogenesis and Metastasis ISBN: 1615045368 ISBN-13(EAN): 9781615045365 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 41580.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proprotein convertases (PCs) are a family of proteases including PC1, PC2, Furin, PC4, PACE4, PC5, and PC7. This title discusses a number of previous and recent findings on the PCs features, their implication in the regulation of multiple cellular functions that impact on the invasive/metastatic potential of cancer cells, and their clinical relevance in cancer patients.
Автор: Brigitte M. Jockusch Название: The Actin Cytoskeleton ISBN: 3319835033 ISBN-13(EAN): 9783319835037 Издательство: Springer Рейтинг: Цена: 260870.00 T Наличие на складе: Поставка под заказ. Описание: In this book on "The Actin Cytoskeleton", twelve internationally renowned authors present specific chapters that cover their recent work concerned with the various roles of actin mentioned above.
Автор: Jonathan M. Lee Название: The Actin Cytoskeleton and the Regulation of Cell Migration ISBN: 1615043888 ISBN-13(EAN): 9781615043880 Издательство: Mare Nostrum (Eurospan) Цена: 61910.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The mammalian cytoskeleton is an internal framework of actin, tubulin, and intermediate filament proteins. Proteins of these three classes assemble non-covalently into filamentous polymers that support the structural integrity of the relatively fragile lipid plasma membrane. In addition, cytoskeletal polymers provide the mechanical strength that hold a cell together and anchor it to its growth substrate. The cytoskeleton must also have the capacity for rapid and substantial remodeling and provide the motive and tractor force necessary to drive motility. As such, the cytoskeleton has a functional duality: sufficiently rigid to prevent plasma membrane deformation but pliable enough to allow for cytokinesis; sufficiently adhesive to allow for traction but dynamic enough to allow movement from one place to another. A major research challenge in cytoskeleton biology is to understand how cytoskeletal proteins assemble and dissemble in support of physiological processes. This chapter will focus on the role of the actin cytoskeleton in cell migration. More specifically, we will focus on the actin cytoskeleton of vertebrate cells.
Название: Metastasis ISBN: 1621823245 ISBN-13(EAN): 9781621823247 Издательство: Неизвестно Рейтинг: Цена: 49140.00 T Наличие на складе: Невозможна поставка. Описание: Nearly all types of cancer have the ability to metastasize, or spread from one organ or tissue in the body to another. Metastatic disease is responsible for the majority of cancer deaths and, therefore, is a critical area of research. Work to better understand the metastatic cascade-how cells detach from a primary tumor, migrate through the body, and seed secondary tumors at distant locations-will lead to improved treatment options for patients with cancer. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding the molecular mechanisms underlying metastasis and how this knowledge is paving the way for new therapeutic targets. The contributors discuss progress in defining mutations that might be driving metastasis, the formation of a premetastatic niche and how it enhances the establishment of a secondary tumor, and how changes that occur during aging increase the metastatic capacity of tumor cells. They also consider the selection and colonization of common target organs (e.g., brain, liver, and bones) during metastasis and the roles of immune cells and extracellular vesicles at different steps of the metastatic cascade. Cellular plasticity-including evidence for metastatic stem cells and the role of tumor cell dormancy in recurrent metastasis-is also covered. In addition, the authors describe the development of in vivo models and techniques for studying metastasis, methods for monitoring tumor progression and metastatic spread (e.g., intravital microscopy and liquid biopsy), and immunotherapies that can potentially target cancer metastasis. This volume is therefore a vital reference for all cancer biologists and clinician-scientists concerned with defeating cancer.
Автор: Ray H. Gavin Название: Cytoskeleton Methods and Protocols ISBN: 1617796492 ISBN-13(EAN): 9781617796494 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In this cutting-edge book, internationally renowned experts present techniques which reflect many of the recent technological advances in experimental tools for cytoskeleton research. There is emphasis on animal, plant, protist, and fungal model systems.
Автор: Gerhard Isenberg Название: Cytoskeleton Proteins ISBN: 3642489613 ISBN-13(EAN): 9783642489617 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The standard protocols for the purification of all known cytoskeleton proteins are presented in this manual. The isolation procedure for each protein is shown in a clear flowchart, while the source of the protein, equipment and material needed, a list of suppliers, standard references, accession No.
Автор: Brigitte M. Jockusch; Eckhard Mandelkow; Klaus Web Название: The Cytoskeleton ISBN: 364279484X ISBN-13(EAN): 9783642794841 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Molecular biology has dissected the functional domains of the motor proteins involved and provided material required for biochemical studies as well as structure analysis by X-ray diffraction and NMR.
Автор: Kermit L. Carraway; Coralie A. C. Carraway; Kermit Название: Signaling and the Cytoskeleton ISBN: 3662129957 ISBN-13(EAN): 9783662129951 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology.
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