This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Kalet Ira J. Название: Principles of Biomedical Informatics, 2 ed ISBN: 0124160190 ISBN-13(EAN): 9780124160194 Издательство: Elsevier Science Рейтинг: Цена: 83080.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides a treatment of the deep computational ideas at the foundation of the field. This book includes exercises at the end of each chapter, ideas for student projects, and a number of new topics, such as: tree structured data, interval trees, and time-oriented medical data and their use.
Название: Computational systems bioinformatics - methods and biomedical applications ISBN: 9812707042 ISBN-13(EAN): 9789812707048 Издательство: World Scientific Publishing Рейтинг: Цена: 100320.00 T Наличие на складе: Невозможна поставка. Описание: Computational systems biology (CSB) is a field of research concerned with understanding the structure and processes of biological systems at the molecular, cellular, tissue, and organ levels through computational modeling as well as novel information theoretic data and image analysis methods. This book introduces the basic principles of CSB.
Автор: Hadi Heidari, Vahid Nabaei Название: Magnetic Sensors for Biomedical Applications ISBN: 1119552176 ISBN-13(EAN): 9781119552178 Издательство: Wiley Рейтинг: Цена: 101320.00 T Наличие на складе: Поставка под заказ. Описание: An important guide that reviews the basics of magnetic biosensor modeling and simulation Magnetic Sensors for Biomedical Applications offers a comprehensive review of magnetic biosensor modelling and simulation. The authors--noted experts on the topic--explore the model's strengths and weaknesses and discuss the competencies of different modelling software, including homemade and commercial (for example Multi-physics modelling software). The section on sensor materials examines promising materials whose properties have been used for sensing action and predicts future smart-materials that have the potential for sensing application.
Next, the authors present classifications of sensors that are divided into different sub-types. They describe their working and highlight important applications that reveal the benefits and drawbacks of relevant designs. The book also contains information on the most recent developments in the field of each sensor type.
This important book: Provides an even treatment of the major foundations of magnetic biosensorsPresents problem solution methods such as analytical and numericalExplains how solution methods complement each other, and offers information on their materials, design, computer aided modelling and simulation, optimization, and device fabricationDescribes modeling work challenges and solutions Written for students in electrical and electronics engineering, physics, chemistry, biomedical engineering, and biology, Magnetic Sensors for Biomedical Applications offers a guide to the principles of biomagnetic sensors, recent developments, and reveals the impact of sensor modelling and simulation on magnetic sensors.
Автор: Azar, Ahmad Taher Название: Control Applications For Biomedical Engineering Systems ISBN: 0128174617 ISBN-13(EAN): 9780128174616 Издательство: Elsevier Science Рейтинг: Цена: 132500.00 T Наличие на складе: Поставка под заказ. Описание:
Control Applications for Biomedical Engineering Systems presents different control engineering and modeling applications in the biomedical field. It is intended for senior undergraduate or graduate students in both control engineering and biomedical engineering programs. For control engineering students, it presents the application of various techniques already learned in theoretical lectures in the biomedical arena. For biomedical engineering students, it presents solutions to various problems in the field using methods commonly used by control engineers.
Computational Learning Approaches to Data Analytics in Biomedical Applications provides a unified framework for biomedical data analysis using varied machine learning and statistical techniques. It presents insights on biomedical data processing, innovative clustering algorithms and techniques, and connections between statistical analysis and clustering. The book introduces and discusses the major problems relating to data analytics, provides a review of influential and state-of-the-art learning algorithms for biomedical applications, reviews cluster validity indices and how to select the appropriate index, and includes an overview of statistical methods that can be applied to increase confidence in the clustering framework and analysis of the results obtained.
Автор: Anuj Tripathi; Jose Savio Melo Название: Advances in Biomaterials for Biomedical Applications ISBN: 9811033277 ISBN-13(EAN): 9789811033278 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine.
Автор: Hans J Griesser Название: Thin film coatings for biomaterials and biomedical applications ISBN: 1782424539 ISBN-13(EAN): 9781782424536 Издательство: Elsevier Science Рейтинг: Цена: 206610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: "
Thin Film Coatings for Biomaterials and Biomedical Applications" discusses the latest information on coatings, including their historic use by scientists who are looking to improve the properties and biological responses of the material-host interface. Thin films, in particular, are becoming more widely researched and used as an alternative to traditional sprayed coatings because they have a more uniform structure and therefore greater stability.
This book provides readers with a comprehensive guide to thin film coatings and their application in the biomaterials field. Part One of the book details the fundamentals of thin films for biomedical application, while Part Two looks at the special properties of thin films, with a final section reviewing functional thin films and their usage in biomedical applications. Provides a comprehensive review on the fundamentals, properties, and functions of thin film coatings for biomaterialsCovers a broad range of applications for implantable biomaterials Written by an international team of contributors who carefully tailor the presented information in a way that addresses industry needs
Автор: Anwar Sunna; Andrew Care; Peter L. Bergquist Название: Peptides and Peptide-based Biomaterials and their Biomedical Applications ISBN: 3319881744 ISBN-13(EAN): 9783319881744 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Поставка под заказ. Описание: Solid-binding peptides have been used increasingly as molecular building blocks in nanobiotechnology as they can direct the assembly and functionalisation of a diverse range of materials and have the ability to regulate the synthesis of nanoparticles and complex nanostructures.
Автор: Seguin Ralph Название: Advances and Diverse Applications of Biomaterials ISBN: 1632380285 ISBN-13(EAN): 9781632380289 Издательство: Неизвестно Цена: 134110.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Eva Pellicer; Danilo Nikolic; Jordi Sort; Maria Ba Название: Advances in Applications of Industrial Biomaterials ISBN: 331987389X ISBN-13(EAN): 9783319873893 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Поставка под заказ. Описание:
Reviews applied biomaterials with nanotechnology aspects in different industries
Includes marine vehicle applications and renewable resources
Gives an insight into both the material developments and production technologies
Polymeric nanomaterials have become increasingly useful for a wide range of applications in therapeutics, tissue engineering and regenerative medicine. This is because their properties, such as stability, size, shape, surface charge, surface chemistry, mechanical strength, porosity, and so on, can be tailored toward the specific functionalities that are required to meet the needs of targeted biomedical application.
Advances In Polymeric Nanomaterials For Biomedical Applications examines advanced polymer synthetic strategies for developing novel biomaterials for use in medicine. With a strong focus on fundamentals and structure, the authors also explore their fabrication, as well as current and potential biomedical applications.
The book begins with a look at the fundamentals of polymeric nanomaterials and their properties. The text goes on to discuss the design of biomaterials and their applications in drug delivery. Further chapters explore other important applications such as imaging and regenerative medicine, including current challenges and future trends.
This valuable resource is especially useful for materials and polymer scientists, and bioengineers wishing to broaden their knowledge of polymeric nanobiomaterials.
Covers the complete spectrum of polymer nanomaterials used in biomedical applications
Includes various applications such as drug delivery, gene delivery, bio-imaging, tissue engineering and regenerative medicine, anti-microbial agents and neuroscience together for the first time in this area
Explores fundamental correlations between structures, properties and applications as well as synthetic strategies for polymer nanomaterials
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