Fungal Siderophores: From Mineral―microbe Interactions to Anti-Pathogenicity, Dhusia Kalyani, Raja Kalpana, Ramteke Pramod

Автор: J. Hacker; J.B. Kaper
Название: Pathogenicity Islands and the Evolution of Pathogenic Microbes
ISBN: 364262720X ISBN-13(EAN): 9783642627200
Издательство: Springer
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Описание: It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes.

Автор: Graham E Jenkins, Joanne I Hall
Название: Autoantibodies: Detection, Pathogenicity & Health Implications
ISBN: 1620815605 ISBN-13(EAN): 9781620815601
Издательство: Nova Science
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Цена: 178450.00 T
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Описание: Autoantibodies that are directed against self antigens are called autoantibodies. Not all autoantibodies are harmful. Autoantibodies can be useful in the removal of cell debris during inflammation. Some autoantibodies may be the actual pathogenic agents of autoimmune disease, the secondary consequences of tissue damage, or the harmless footprints of an etiologic agent. In this book, the authors present current research in the detection, pathogenicity and health implications of autoantibodies. Topics include the implicated autoantibodies in kidney disease and Alzheimers disease; autoimmunity in cardiovascular disease; detection and analysis of natural autoantibodies; and B Cells and autoantibodies in multiple sclerosis.

Автор: Stuart B. Levy
Название: Molecular Biology, Pathogenicity, and Ecology of Bacterial Plasmids
ISBN: 1468439855 ISBN-13(EAN): 9781468439854
Издательство: Springer
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Цена: 93160.00 T
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Описание: This book resulted from presentations at an international conference on bacterial p1asmids held January 5-9, 1981 in Santo Domingo, Dominican Republic. Diseases and socio-economic practices of developing countries exist in the Dominican Republic whose scientific community could directly benefit from having the meeting there.

Автор: W. Goebel
Название: Genetic Approaches to Microbial Pathogenicity
ISBN: 364270588X ISBN-13(EAN): 9783642705885
Издательство: Springer
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Цена: 121110.00 T
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Описание: Important progress in the elucidation of the mechanisms influencing bacterial pathogenicity has recently been made through the introduction of modem genetic techniques. Molecular cloning allows the isolation of genes for pheno- types that epidemiological surveys have suggested play an important role in pathogenesis. The structural analysis of determinants for pathogenic traits can lead to the identifica- tion not only of the primary sequence but also of the possi- ble secondary and tertiary structures for important viru- lence factors such as toxins and adhesins. From these data, the prediction of antigenic domains suitable for the devel- opment of new vaccines appears to be feasible. The regula- tion of virulence determinants by endogenous and exoge- nous factors can be more clearly understood through the functional analysis of the cloned virulence genes. This volume surveys representative virulence properties of gram-positive and gram-negative bacteria to which the genetic approach has been successfully applied. The exam- ples described here include important bacterial toxins (e.g., diphtheria toxin, cholera toxin, toxic shock syndrome toxin, hemolysins), adhesion structures from E. coli and Neisseria gonorrhoeae, and factors supporting iron uptake, serum resistance, and invasiveness in a variety of bacteria. Both the present state and the possible futural develop- ments of these systems are described.

Автор: Jos? P?rez Mart?n; Antonio Di Pietro
Название: Morphogenesis and Pathogenicity in Fungi
ISBN: 3642428347 ISBN-13(EAN): 9783642428340
Издательство: Springer
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Цена: 156720.00 T
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Описание: This book combines state-of-the-art expertise from a variety of diverse pathogen model systems to provide an update to our current understanding of the regulation of fungal morphogenesis as a key determinant of pathogenicity in fungi.

Автор: J. Slais
Название: The Morphology and Pathogenicity of the Bladder Worms
ISBN: 9061932505 ISBN-13(EAN): 9789061932505
Издательство: Springer
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Цена: 81050.00 T
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Описание: The larval stage of taeniid cestodes, called the cysticercus, develops in the intermediate host from the oncosphere. The infection caused by cysticerci is called cysticercosis. Man is the only definitive host of two adult cestode species. One of them is the cestode Taenia solium Linne, 1758. Its larva is called Cysticercus cellulosae developing mostly in the muscles of swine. The other is Taeniarhynchus saginatus Goeze, 1782 and its larva Cysticercus bovis (C. inermis) develops in the muscles of cattle. Man can carry a cysticercus being its intermediate host, and suffer from cysticercosis. Because cysticerci are localized in the muscles of livestock, various measures have to be taken to prevent an infection of man with the adult cestode. These include a very strict inspection of the carcasses at the abattoir, a special treatment of infected meat or a certificate declaring it unfit for human consumption. The incidence of hu- man tapeworms, being still relatively high in the population, can be controlled suc- cessfully only by a comprehensive programme of eradication of muscle cysticercosis. There is no exact information available on fundamental processes in the biology of the cysticercus such as its development, its initial growth in the muscles, its meta- bolism, the length of its life, the reaction of the host, the possibility of spontaneous healing. Such knowledge is not only of theoretical importance, but indispensable for successful control of the parasites and for the serological diagnosis of cysticercosis.

Автор: Hameed
Название: Pathogenicity and Drug Resistance of Human Pathogens
ISBN: 9813294485 ISBN-13(EAN): 9789813294486
Издательство: Springer
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Цена: 186330.00 T
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Описание:

Chapter 1. Pathogenicity and Drug resistance in Mycobacterium tuberculosis.- Chapter 1.1. Overview of tuberculosis pathogenesis.- Chapter 1.2. Response of Mycobacterium Tuberculosis to pH stress.- Chapter 1.3. Recent advances in Diagnosis of Tuberculosis.- Chapter 1.4. Molecular basis of Drug Resistance in Mycobacteria.- Chapter 1.5. Eliminating Mycobacterial persisters: novel targets for anti-TB therapy.- Chapter 1.6. Roadmap for the eradication of MDR-TB.- Chapter 2. Candida infections and therapeutic strategies.- Chapter 2.1. Fungal diseases and their treatment: a holistic approach.- Chapter 2.2. Anti-Candida therapeutics: mechanisms, resistance and safer phytomedicinal approaches.- Chapter 2.3. Mitochondria and drug resistance in Candida.- Chapter 2.4. Mechanism of Anti-Fungal for cutaneous infections: preventive potential, mechanism and treatment.- Chapter 3. Malarial parasite biology.- Chapter 3.1. Drug targets in Malarial parasites.- Chapter 3.2. Pathogenic mechanism and signaling pathways in Plasmodium.- Chapter 3.3. Mechanism of Drug Resistance in Plasmodium.- Chapter 3.4. Novel antimalarial drug targets.- Chapter 3.5. Novel therapeutic targets in malaria.- Chapter 4. Emerging Viral Diseases.- Chapter 4.1. Hepatitis C Virus and innate interferon response.- Chapter 4.1.1. Pathogen biology.- Chapter 4.1.2. Drug resistance.- Chapter 4.1.3. Novel drug targets and therapeutic strategies.- Chapter 4.2. Epidemiological trends and current challenges in Ebola.- Chapter 4.2.1. Pathogen biology.- Chapter 4.2.2.Drug resistance.- Chapter 4.2.3. Novel drug targets and therapeutic strategies.- Chapter 4.3. Prions diseases: a concern for mankind.- Chapter 5. Translational Research in Human Microbes.- Chapter 5.1. Harnessing microbiota as anti-infectives.- Chapter 5.2. Human microbiome and malignancy: principles, mechanisms and challenges.- Chapter 5.3. Current and future perspectives of nanobiotechnology: in combating microbial pathogenesis.- Chapter 5.4. Microbes in reproductive tract system: inferences from microbial world.- Chapter 5.5. miRNAs in infectious diseases.- Chapter 5.6. Application of bioinformatics in combating infectious diseases.

Автор: Christophe Lacomme; Laurent Glais; Dirk U. Bellste
Название: Potato virus Y: biodiversity, pathogenicity, epidemiology and management
ISBN: 3319864939 ISBN-13(EAN): 9783319864938
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Поставка под заказ.
Описание: Potato virus Y (PVY) infects a wide host range mainly within the Solanaceae and is distributed worldwide. PVY is transmitted by more than 40 aphid species in a non persistent manner. Isolates of the PVY species are highly variable at biological, serological and molecular levels. Epidemiological studies have highlighted the emergence of distinct potato PVY variants able to induce necroses on potato tubers. Due to the lack of efficient resistance to PVY isolates inducing necrotic symptoms in cultivated varieties and the plant-to-plant transmission of isolates through the daughter tubers, PVY has become the most economically important virus for the potato industry. The review offers an overview of several decades of research on PVY but also focuses on the latest data obtained by expert on PVY worldwide on the biological characteristics of PVY, interactions between aphids-hosts, its evolution and management. Identified knowledge gaps to understand further PVY biology will be discussed.