Lipid Signaling in Human Diseases, Gomez-Cambronero Julian, Frohman Michael A.

Автор: Senthilkumar Rajagopal; Murugavel Ponnusamy
Название: Calcium Signaling: From Physiology to Diseases
ISBN: 9811353336 ISBN-13(EAN): 9789811353338
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Нет в наличии.
Описание: This book focuses on disorders of calcium channels and the use of drugs to treat calcium-related disorders and their associated toxicities.

Автор: Mark Waugh
Название: Lipid Signaling Protocols
ISBN: 1493931695 ISBN-13(EAN): 9781493931699
Издательство: Springer
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Цена: 130430.00 T
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Описание:

In this second edition methods are described to measure the synthesis of lipids such as the phosphoinositides, ceramides and sphingomyelin, as well as techniques to molecularly characterize the various kinases and phosphatases that regulate the intracellular metabolism of these lipids. Lipid Signaling Protocols, Second Edition guides readers through detailed experimental protocols, which are complimented by review chapters that highlight the technical considerations, challenges and potential pitfalls associated with using these laboratory-based approaches. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, Lipid Signaling Protocols, Second Edition aims to ensure successful results in the further study of this vital field.

Автор: Rakesh Srivastava
Название: Apoptosis, Cell Signaling, and Human Diseases
ISBN: 1617377139 ISBN-13(EAN): 9781617377136
Издательство: Springer
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Цена: 148010.00 T
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Описание: These volumes present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways.

Автор: Rakesh Srivastava
Название: Apoptosis, Cell Signaling, and Human Diseases
ISBN: 1617378232 ISBN-13(EAN): 9781617378232
Издательство: Springer
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Цена: 174130.00 T
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Описание: Apoptosis, Cell Signaling, and Human Diseases: Molecular Mechanisms, Volumes 1 and 2, present a concise synthesis of recent developments in the understanding of both cell survival and apoptotic pathways. Particular attention is given to apoptosis in human diseases, such as different forms of cancer.

Название: JAK-STAT Signaling in Diseases
ISBN: 1138487627 ISBN-13(EAN): 9781138487628
Издательство: Taylor&Francis
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Цена: 132710.00 T
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Описание: This book discusses the role of Jak-STAT signaling in autoimmune and inflammatory diseases including Asthma, Hepatic fibrosis, Diabetes, Cancer, Inflammatory Bowel Disease, Severe Combined Immunodeficiency, Rheumatoid Arthritis, Dermatology, HIV, Multiple Sclerosis, Renal disorders and Organ Transplantation.

Автор: Ariel Ruiz i Altaba
Название: Hedgehog-Gli Signaling in Human Disease
ISBN: 1489989765 ISBN-13(EAN): 9781489989765
Издательство: Springer
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Цена: 174130.00 T
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Описание: The aim of the book is to disseminate information on this exciting field, to allow students, scientists and the public in general to gain access current information from research leaders and to provide a book that encompasses different aspects of research showing the fusion of basic research in model systems and medicine.

Автор: Teun Munnik
Название: Lipid Signaling in Plants
ISBN: 3642261868 ISBN-13(EAN): 9783642261862
Издательство: Springer
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Цена: 213360.00 T
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Описание: This comprehensive update on plant lipid signaling covers the measurement, regulation and function of phospholipases, lipid kinases, lipid phosphatases, inositolpolphosphates, polyphosphoinositides, phosphatic acid, and other lipid signals such as oxylipins.

Автор: Teun Munnik
Название: Lipid Signaling in Plants
ISBN: 3642038727 ISBN-13(EAN): 9783642038723
Издательство: Springer
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Цена: 213360.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive update on plant lipid signaling covers the measurement, regulation and function of phospholipases, lipid kinases, lipid phosphatases, inositolpolphosphates, polyphosphoinositides, phosphatic acid, and other lipid signals such as oxylipins.

Автор: Jingwu Xie
Название: Hedgehog signaling activation in human cancer and its clinical implications
ISBN: 1489995412 ISBN-13(EAN): 9781489995414
Издательство: Springer
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Цена: 174130.00 T
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Описание: Understanding the role of hedgehog signaling in cancer is critically important for novel cancer therapeutics in humans. This volume provides insightful views suitable for clinical scientists, and graduate and undergraduate students alike.

Автор: Banafsh? Larijani; Rudiger Woscholski; Colin A. Ro
Название: Lipid Signaling Protocols
ISBN: 1627038825 ISBN-13(EAN): 9781627038829
Издательство: Springer
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Цена: 135090.00 T
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Описание: In a single volume this book assembles the various tools and methodologies needed by the interested investigator to unravel lipid dependent signaling and cell function. This is an essential resource for both experienced and novice researchers.

Автор: Teun Munnik; Ingo Heilmann
Название: Plant Lipid Signaling Protocols
ISBN: 1493959271 ISBN-13(EAN): 9781493959273
Издательство: Springer
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Цена: 111790.00 T
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Описание: This book presents timely and important tools needed to elucidate particular roles of phosphoinositides in plants. It includes easy-to-use, reproducible protocols and contains expert tips on troubleshooting and avoiding known pitfalls.

Автор: Nils Thomas, Sten Jonathan
Название: Lipid Rafts: Properties and Role in Signaling
ISBN: 1536136247 ISBN-13(EAN): 9781536136241
Издательство: Nova Science
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Цена: 122490.00 T
Наличие на складе: Невозможна поставка.
Описание: Lipid rafts are nanometer-sized subdomains of the plasma membrane containing higher concentrations of cholesterol, phosphatidylinositols, and sphingolipids. In Lipid Rafts: Properties and Role in Signaling, the authors summarize their observations that receptor preassembly is required for biological function; the interaction between receptor chains requires both the presence of Jak1 and their co-nanolocalization within lipid raft; a sequence-supported structural analysis of Janus kinases that suggests a significant influence of phospholipids on Janus kinase function; and critical observations made by others. The authors go on to discuss the way in which some studies have pointed out the relative contribution of microdomain lipid raft abnormalities to the pathophysiology of cardiovascular disease or cancer, and examples of substances known to affect lateral membrane organization in cells are discussed as potential therapeutics. A mini-review is included which summarizes the present data behind the relevance of lipid raft membrane domains in neuronal survival and death, with a particular emphasis in age-related neurodegenerative diseases. Furthermore, the emerging importance of the lipid matrix in alpha-synuclein protein configurations in synucleopathies will also be discussed. Lastly, the authors attempt to understand the molecular background of low-solubility of neuronal membrane to non-ionic detergent and find that phosphatidylserine prepared from brain showed insolubility to Triton X-100 at 4℃. Additionally, it was found that some lipid-derived molecules increased the solubility of neuronal DRM to non-ionic detergents.