Nrf2 and Its Modulation in Inflammation, Deng Huai

Автор: Ross G. Cameron; George Feuer
Название: Apoptosis and Its Modulation by Drugs
ISBN: 3642630251 ISBN-13(EAN): 9783642630255
Издательство: Springer
Рейтинг:
Цена: 348290.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: with contributions by numerous experts

Автор: Ross G. Cameron; George Feuer
Название: Apoptosis and Its Modulation by Drugs
ISBN: 3540661212 ISBN-13(EAN): 9783540661214
Издательство: Springer
Рейтинг:
Цена: 391830.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: with contributions by numerous experts

Автор: Palese, Peter (Ed.)
Название: Modulation of Host Gene Expression and Innate Immunity by Viruses
ISBN: 9048168236 ISBN-13(EAN): 9789048168231
Издательство: Springer
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Цена: 194730.00 T
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Описание: Ulrich Desselberger, Gif-sur-Yvette/Cambridge.Infection of a naive (non-immune) host with a virus elicits an immediate response which results in a cascade of changes in the host, including an interferon response (innate immunity).

Автор: Karl Pummer
Название: Biological Modulation of Solid Tumours by Interferons
ISBN: 3642788688 ISBN-13(EAN): 9783642788680
Издательство: Springer
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Цена: 121110.00 T
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Описание: For this purpose, after two chapters of general aspects of interferon action and interaction, selected solid tumours which are commonly considered difficult to treat in advanced stages are discussed with respect to both preclinical data and clinical experience.

Автор: A Di Cerbo, B Palmieri, Maria Aponte
Название: Immune Modulation by Probiotics: State of the Art
ISBN: 1629489549 ISBN-13(EAN): 9781629489544
Издательство: Nova Science
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Цена: 205910.00 T
Наличие на складе: Невозможна поставка.
Описание: There have been dramatic changes in the technologies available for hemodynamic monitoring in recent years. This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside and evaluating hemodynamic monitoring systems in clinical practice.

Автор: Avia Rosenhouse-Dantsker; Anna N. Bukiya
Название: Cholesterol Modulation of Protein Function
ISBN: 3030042774 ISBN-13(EAN): 9783030042776
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, renowned scientists describe the role of steroid chirality and modification of lipid membrane physical properties in the modulation of G protein-coupled receptors and ion channels. The application of commonly-used technical approaches such as mass spectrometry and nucleic magnetic resonance transfer spectroscopy for studies on cholesterol distribution and alteration of lipid bilayer characteristics is also discussed. This book offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via mechanisms that extend beyond lipid-protein direct interactions. In the first part, the chapters introduce the reader to the use of the chemical derivatives of cholesterol as a valuable laboratory tool in the studies of cholesterol-driven modulation of protein function. In the second part, examples of cholesterol-induced changes in membrane physical characteristics are presented and discussed in light of their multifaceted contribution to the effect of cholesterol on protein function. The book will be of interest to undergraduate and graduate students as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.

Автор: Chakraborti Sajal, Dhalla Naranjan S., Dikshit Madhu
Название: Modulation of Oxidative Stress in Heart Disease
ISBN: 9811389454 ISBN-13(EAN): 9789811389450
Издательство: Springer
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Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book highlights the multifaceted roles of Reactive Oxygen Species (ROS) in modulating normal cellular and molecular mechanisms during the development of different types of heart disease. Each chapter in the book deals with the role that altered redox homeostasis plays in the pathophysiology of heart disease. In addition, the book explains how reactive oxidant species interact with their targets and provides novel strategies for attenuating oxidative stress-induced types of heart disease. The book not only covers ROS-induced response in heart disease at the cellular level, but also demonstrates that an imbalance of redox states has its roots in our genes, and explains the ways gene expression is regulated. In turn, it reviews potential sources of ROS, their pathological effects on the heart, and potential sites for therapeutic interventions.

Автор: Corrado L. Galli; Marina Marinovich; Alan M. Goldb
Название: Modulation of Cellular Responses in Toxicity
ISBN: 3642798748 ISBN-13(EAN): 9783642798740
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of the NATO Advanced Study Institute on the Modulation of Cellular Response in Toxicity, held in Ponte di Legno, Italy , January 24 - February 3, 1994.

Автор: Stephens Gary
Название: Modulation of Presynaptic Calcium Channels
ISBN: 9400763336 ISBN-13(EAN): 9789400763333
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book presents recent advances in knowledge of the regulation of presynaptic Ca2+ channels. These represent one of the most widely modulated proteins in the body, target of a range of effector pathways and drugs; this range will be fully represented here.

Автор: Mohinder Bansal; Naveen Kaushal
Название: Oxidative Stress Mechanisms and their Modulation
ISBN: 8132228790 ISBN-13(EAN): 9788132228790
Издательство: Springer
Рейтинг:
Цена: 113180.00 T
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Описание: This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book.

Автор: Mohinder Bansal; Naveen Kaushal
Название: Oxidative Stress Mechanisms and their Modulation
ISBN: 8132220315 ISBN-13(EAN): 9788132220312
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Research over the years has demonstrated that free radicals mediated oxidative stress lies at the helm of almost all patho-physiological phenomena. These findings emphasize on the need to understand the underlying molecular mechanism(s) and their critical role in the pathogenesis. This book aims to focus on these areas to provide readers a comprehensive outlook about the major redox sensitive pathways and networks involved in various disease conditions. In the first chapter of the book, basic information about the oxidative stress, its generation, its biomarkers and its role in body are discussed. In the next three chapters, the role of oxidative stress in various pathologies ranging from neurological disorders, to cardiovascular diseases, cancers, metabolic diseases and ageing have been described. Chapter 5 cumulatively describes the most important molecular signaling pathways that are affected by reactive oxygen species (ROS). These are the mechanisms which are common denominators in various pathological states. In the next part of the book, various antioxidant strategies to target and mitigate ROS have been discussed with details on the mechanisms. Selenium, being the research focus and interest of the authors for years, the role of selenium as an antioxidant as part of selenoproteins has been included in the book. Finally, the book culminates with authors’ perspective on the future of the redox biology field. Throughout the book, efforts have been made to use simplified language and suitable figures for ease to understand the contents. Although the authors have tried to touch on all the different aspects of oxidative stress in detail, the fact that it is a continuously growing field with updates coming every day, there might be some areas which might not be described in depth. This book is designed for students, young scientists to get acquainted with the redox biology. Overall, this book is a reference to understand the redox regulation of cellular signaling pathways involved in pathogenesis.

Автор: Rosenhouse-Dantsker Avia, Bukiya Anna N.
Название: Direct Mechanisms in Cholesterol Modulation of Protein Function
ISBN: 3030142647 ISBN-13(EAN): 9783030142643
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this book, renowned scientists describe how cholesterol interacts with various proteins. Recent progress made in the high-resolution visualization of cholesterol-protein interactions using crystallography and cryogenic electron microscopy has substantially advanced the knowledge of critical features. These features enable specific recognition of the cholesterol molecule by proteins, a process that was built on earlier studies using binding assays, computational modeling and site-directed mutagenesis. Direct Mechanisms in Cholesterol Modulation of Protein Function offers comprehensive insights into the current understanding of cholesterol-driven modulation of protein function via direct sensing. Its nine chapters are organized into two distinct parts. In the first part, the chapters introduce the reader to the general characteristics of cholesterol binding sites in proteins. This part starts with a tour into common cholesterol recognition motifs, followed by an overview of the major classes of steroid-binding proteins. It then continues with two chapters that present a comprehensive analysis of molecular and structural characteristics of cholesterol binding sites in transmembrane and soluble protein domains. In the second part of the book, examples of cholesterol binding sites and consequences of specific cholesterol recognition for protein function are presented for G protein-coupled receptors, ion channels and cholesterol-transporting proteins. The book is valuable for undergraduate and graduate students in biochemistry and nutrition, as well as basic science and medical researchers with a keen interest in the biophysical properties of cholesterol and physiological consequences of cholesterol presence in biological systems.