Автор: Harper Joyce C. Название: Preimplantation genetic diagnosis ISBN: 0521884713 ISBN-13(EAN): 9780521884716 Издательство: Cambridge Academ Рейтинг: Цена: 85750.00 T Наличие на складе: Есть Описание: Preimplantation genetic diagnosis (PGD) is a key technique in modern reproductive medicine. Originally developed to help couples who were at risk of transmitting single-gene genetic abnormalities to their children, the development of the FISH technique broadened chromosome analysis to include detection of more complex inherited abnormalities. The last decade has seen the development of aneuploidy screening (PGS) for infertile couples, using the same techniques as PGD but screening for as many chromosomes as possible. PGD has always been a controversial procedure and embryo manipulation and selection is still illegal in some countries. The second edition of this leading textbook describes all aspects of PGD, with chapters written by key international experts in the field. A must for anyone interested in learning more about PGD, it will be of interest to everyone working in the fields of IVF, genetic diagnosis, genetic counselling, and prenatal diagnosis - including clinicians, embryologists, nurses, and clinical scientists.
Автор: Sills, E. Название: Sills-Human Embryos and Preimplantation Technologies ISBN: 0128164689 ISBN-13(EAN): 9780128164686 Издательство: Elsevier Science Рейтинг: Цена: 218960.00 T Наличие на складе: Нет в наличии. Описание:
Regularly used to determine the health and viability of an embryo before in vitro fertilization, preimplantation genetic screening (PGS) and preimplantation genetic diagnosis (PGD) have been successfully employed to test embryonic cells for chromosomal abnormalities and genes related to specific diseases. However, the complex social, ethical, legal, regulatory, and public policy aspects associated with preimplantation assessment technologies continue to evolve and represent important areas for scholarly discussion.
Human Embryos and Preimplantation Technologies: Social, Legal, and Health Policy Dimensions of Assisted Reproduction, edited by leading experts in the field, Dr. E. Scott Sills and Dr. Gianpiero Palermo, stands as the first holistic analysis of PGD and PGS as practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides international perspectives on the ethical, legal, religious, policy, and social implications of assisted reproduction technologies globally, including in Africa, Asia, Europe, North and South America, and Australia.
The book begins with a thorough overview of PGS and PGD, featuring chapters on the history of these technologies, ethics, and social perspectives including PGS and the LGBT community, feminism, family dynamics, and psychological and interpersonal factors involved with assessment. Part II considers the current state of PGD and PGS in 20 different sovereign nations and religious communities, employing data on reproductive tourism and elective sex selection of human embryos. Part III concludes the book with an analysis of public policy concerns, current challenges, and future directions of PGS and PGD.
Provides in-depth discussion of PGD and PGS as practiced and regulated worldwide
Offers an accessible resource for researchers, medical professionals, patients, regulators, and policymakers seeking expert opinions on PGS and PGD
Chapters contributed by international clinicians, researchers, and thought leaders in the field of assisted reproductive technology
Автор: David K. Gardner; Denny Sakkas; Emre Seli; Dagan W Название: Human Gametes and Preimplantation Embryos ISBN: 1493942689 ISBN-13(EAN): 9781493942688 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.
Автор: Barry D. Bavister Название: Preimplantation Embryo Development ISBN: 1461393191 ISBN-13(EAN): 9781461393191 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume contains the Proceedings of the Serono Symposium on Pre- implantation Embryo Development, held in Newton, Massachusetts, in 1991. The idea for the symposium grew out of the 1989 Serono Symposium on Fertilization in Mammals* at which preimplantation development was the predominant suggestion for a follow-up topic.
Автор: A. Kuliev; Yury Verlinsky Название: Preimplantation Genetics ISBN: 1468413538 ISBN-13(EAN): 9781468413533 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Yury Verlinskyand Anver Kuliev Reproductive Genetics Institute, Illinois Masonic Medical Center, 836 W. Wellington chicago, IL 60657 Although introduction of a first trimester prenatal diagnosis by chorionic viIIus sampling (CVS) has considerably improved the possibility for prevention of genetic diseases, it requires a selective abortion in case of an affected fetus. Following the direction of an earlier prenatal diagnosis and to avoid the need for abortion, preimplantation genetic diagnosis has been initiated based on polar body removal and pre-embryo biopsy. The First International symposium on Preimplantation Genetics, Chicago, September 17-19, 1990, was organized to explore these important developments, to review the state of knowledge in the field, and to address existing problems to be solved for developing and improving current approaches for preimplantation diagnosis of genetic disorders. A growing interest in the subject was obvious from the wide attendance of the meeting: over 250 scientists from 19 countries participated. This was the first attempt to put together the advances in different areas of basic and applied research relevant to Preimplantation Genetic Diagnosis, with the multidisciplinary scientific program including the sessions on embryology, micromanipulation and biopsy, genetic analysis of gametes and pre-embryos, IVF, gene expression and gene therapy, and ethical and legal issues. The deliberations of the Symposium presented in the above mentioned sessions, which comprise the contents of correspond- ing sections of the Proceedings, open a newarea in medical research based on the interaction of IVF and New Genetics.
Название: Preimplantation Genetic Testing ISBN: 1138333417 ISBN-13(EAN): 9781138333413 Издательство: Taylor&Francis Рейтинг: Цена: 219470.00 T Наличие на складе: Невозможна поставка. Описание: Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease.
Название: Preimplantation Genetic Testing ISBN: 1138333301 ISBN-13(EAN): 9781138333307 Издательство: Taylor&Francis Рейтинг: Цена: 88800.00 T Наличие на складе: Невозможна поставка. Описание: Preimplantation genetic testing (PGT) is now well established as a valuable treatment option for patients wishing to start or continue a family, for a range of indications from advanced maternal age to high risk of transmitting inherited disease.
Автор: Yuri Verlinsky Название: An Atlas of Preimplantation Genetic Diagnosis ISBN: 185070760X ISBN-13(EAN): 9781850707608 Издательство: Elsevier Science Цена: 51080.00 T Наличие на складе: Нет в наличии.
Автор: Bayefsky Название: Regulating Preimplantation Genetic Diagnosis in the United States ISBN: 1137515430 ISBN-13(EAN): 9781137515438 Издательство: Springer Рейтинг: Цена: 51230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reproductive technology allows us to test embryos` genes before deciding whether to transfer them to a woman`s uterus. Embryo selection raises many ethical questions but is virtually unregulated in the United States. This comprehensive study considers the ethical, medical, political, and economic aspects of developing appropriate regulation.
Автор: El-Toukhy Название: Preimplantation Genetic Diagnosis in Clinical Practice ISBN: 1447129474 ISBN-13(EAN): 9781447129479 Издательство: Springer Рейтинг: Цена: 60550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers a comprehensive, coherent, up-to-date and practical guide to PGD, from procedures to new clinical and laboratory practice to perspectives on ethical and social issues. Useful both in practice and for answering patient enquiries.
Автор: DePamphilis, Melvin L Название: Mammalian Preimplantation Development,120 ISBN: 0128014288 ISBN-13(EAN): 9780128014288 Издательство: Elsevier Science Рейтинг: Цена: 174050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mammalian Preimplantation Development, the latest volume in the Current Topics in Developmental Biology series covers mammalian preimplantation development, and includes contributions from an international board of authors. The book's chapters provide a comprehensive set of reviews covering such topics as cell proliferation, cell differentiation, and biological significance.
Автор: Barry D. Bavister Название: The Mammalian Preimplantation Embryo ISBN: 1468453343 ISBN-13(EAN): 9781468453348 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With a few notable exceptions, mammalian preimplantation embryos grown in vitro are likely to exhibit sub-optimal or retarded development.
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