Chronic Myeloid Leukemia: Methods and Protocols, Li Shaoguang, Zhang Haojian

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493913921 ISBN-13(EAN): 9781493913923
Издательство: Springer
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Цена: 167700.00 T
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Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Fortina Paolo, Londin Eric, Park Jason Y.
Название: Acute Myeloid Leukemia: Methods and Protocols
ISBN: 1493983962 ISBN-13(EAN): 9781493983964
Издательство: Springer
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Цена: 130430.00 T
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Описание: This volume describes up-to-date techniques used in understanding the molecular biology of acute myeloid leukemia (AML) and addressing advances in diagnosis, classification, prognostication, and therapeutic strategies to potentially impact overall patient survival.

Автор: Celalettin Ustun
Название: Chronic Myeloid Leukemia: From Daily Management to Complicated Issues
ISBN: 1629489719 ISBN-13(EAN): 9781629489711
Издательство: Nova Science
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Цена: 267160.00 T
Наличие на складе: Невозможна поставка.
Описание: Targeted therapy has revolutionised modern oncology practice and has completely changed the outcome of once universally fatal diseases like chronic myeloid leukaemia (CML). The last decade has witnessed significant advances in the management of CML, which has become more like a chronic disease. Written by experts in the field, this volume nicely describes the current knowledge of the pathophysiology, clinical features, and management of CML. It covers not only clinical topics but also the basic science underlying these practices. It will be of help to clinicians and basic scientists alike. In addition to the state of the art treatment of CML, this book also covers many uncommon but very important special topics like management of CML in pregnancy or with children, management of resistance to new tyrosine kinases and treatment of the advanced phase of the disease. Written to be easily digestible, patients will also be able to access important and universally useful information on CML (eg: diagnosis, symptoms and signs, and treatment). Some themes especially, including drug and food interactions of tyrosine kinase inhibitors (TKIs), CML treatment during pregnancy, advantages/disadvantages of the most commonly used TKIs, and bone marrow transplantation indications, will be of popular concern. This extensively referenced book therefore should be of great help to both novices and experts in the field.

Название: Chronic Myeloid Leukemia
ISBN: 0367453304 ISBN-13(EAN): 9780367453305
Издательство: Taylor&Francis
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Цена: 60220.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chronic Myeloid Leukemia (CML) remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level and has been used by researchers to develop a variety of therapies and therapeutic assessment methods. This concise, readable guide assembles and synthesizes the latest developments and tr

Автор: Michael Andreeff
Название: Targeted Therapy of Acute Myeloid Leukemia
ISBN: 1493939890 ISBN-13(EAN): 9781493939893
Издательство: Springer
Рейтинг:
Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies that have been developed during the last decade and are now being evaluated in early clinical trials. Paired and authoritative chapters by leading research scientists and clinicians explain basic concepts and clinical translation of topics that include the underlying genetic and proteomic abnormalities of AML, the development of novel nucleoside analogues, the roles of microRNAs, apoptosis regulators Bcl-2 and p53 and of critical cell signaling proteins such as PIM, FLT3, Raf/MEK, PI3K/AKT/mTOR and aurora kinases. Chapters on epigenetic mechanisms, nuclear receptors, cell surface antigens, the hypoxic leukemia microenvironment, stem cells and leukemia metabolism provide insights into leukemia cell vulnerabilities. Cell therapies utilizing T-, NK- and mesenchymal stem cells and progress in hematopoietic transplantation strategies round up this overview of the multi-dimensional therapeutic landscape in which leukemia specialists develop treatment strategies that are expected to make "leukemia history" in the near future.

Автор: Juan M Garza
Название: Acute Myeloid Leukemia: Signs/Symptoms, Classification & Treatment Options
ISBN: 1634838785 ISBN-13(EAN): 9781634838788
Издательство: Nova Science
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Цена: 168950.00 T
Наличие на складе: Невозможна поставка.
Описание: Brings together Arthur Green`s scholarly writings, centred on the history of early Hasidism, and his highly personal approach to a rebirth of Jewish spirituality in our own day. In choosing to present them in this way he asserts a claim that they are all of a piece. They represent one man`s attempt to wade through history and text, language and symbol, and an array of voices both past and present.

Автор: Richard Greil; Lisa Pleyer; Daniel Neureiter; Vikt
Название: Chronic Myeloid Neoplasias and Clonal Overlap Syndromes
ISBN: 3709120039 ISBN-13(EAN): 9783709120033
Издательство: Springer
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Цена: 204970.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction The understanding of the genetic, epigenetic, immuno- well as for practicing hematologists or oncologists. logical and biological causes of myeloproliferative dis- Each chapter follows a similar architecture and leads orders has substantially improved in the last few years. through epidemiology, genetic and molecular causes, Together with refined tools in pathology, the successful hematological and clinical findings, prognostic factors establishment of mouse models mimicking at least some and current treatment approaches of the diseases. of the myeloproliferative disorders, and murine models Effort has been made to point out the evolving field of novel drugs in this arena but simultaneously diff- allowing to carefully dissect the role of mutations and gene dosage effects of, for example JAK2, this has led to entiate between standard and experimental treatment ever increasing numbers of modified classification approaches. schemes. It is therefore important for the heamtologist Together with the co-editors and all the authors of or oncologist to keep up with this rapid change in classi- the various chapters I hope that the readers of the book fication language, the upcoming of new entities or differ- will enjoy reading and benefit from the information entiation between, or subclassification of, rare diseases provided.

Автор: Shaoguang Li; Haojian Zhang
Название: Chronic Myeloid Leukemia
ISBN: 1493940090 ISBN-13(EAN): 9781493940097
Издательство: Springer
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Цена: 121110.00 T
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Описание:

1. Molecular Detection of BCR-ABL in Chronic Myeloid Leukemia

Автор: Griffin Matthew
Название: Encyclopedia of Myeloid Leukemia: Volume II
ISBN: 1632411725 ISBN-13(EAN): 9781632411723
Издательство: Неизвестно
Цена: 123380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a contribution by various experts from around the world, including America, Europe, Africa and Asia who have worked in the fields of myeloid cell biology and myeloid leukemia pathogenesis. The book aims to provide reviews about new developmen

Автор: Griffin Matthew
Название: Encyclopedia of Myeloid Leukemia: Volume I
ISBN: 1632411717 ISBN-13(EAN): 9781632411716
Издательство: Неизвестно
Цена: 134050.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is a contribution by various experts from around the world, including America, Europe, Africa and Asia who have worked in the fields of myeloid cell biology and myeloid leukemia pathogenesis. The book aims to provide reviews about new developmen

Автор: W. Hiddemann; R. Mertelsmann
Название: New Findings on Aclarubicin in the Treatment of Acute Myeloid Leukemia
ISBN: 3540526137 ISBN-13(EAN): 9783540526131
Издательство: Springer
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Цена: 102480.00 T
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Описание: Provides information about the current status of aclacinomycin A for the treatment of haematologic malignancies. The text includes accounts of the action of aclacinomycin A in myelodysplastic syndromes and of its efficacy in acute myeloid leukemias.

Автор: Carella
Название: Chronic Myeloid Leukaemia
ISBN: 185317890X ISBN-13(EAN): 9781853178900
Издательство: Informa
Рейтинг:
Цена: 105910.00 T
Наличие на складе: Нет в наличии.
Описание: Drawing on the expertise of an international team of experts in chronic myeloid leukemia, this book provides insight into the latest advances and the implications those developments have for management of the disease. The editors and their panel of contributors explore many topics, including a review of molecular and cellular biology, a discussion of conventional chemotherapy and interferon therapy, and recent developments in allografting and autografting. The reader gains not only an incisive view of the biological structure of the disease, but applications of that biology to treatment modalities. The book emphasizes treatment strategies and is a guide to complex treatment options.