Essential information for architects, designers, engineers, equipment suppliers, and other professionals who are working in or entering the biopharmaceutical manufacturing field
Biomanufacturing facilities that are designed and built today are radically different than in the past. The vital information and knowledge needed to design and construct these increasingly sophisticated biopharmaceutical manufacturing facilities is difficult to find in published literature--and it's rarely taught in architecture or design schools. This is the first book for architects and designers that fills this void. Process Architecture in Biomanufacturing Facility Design provides information on design principles of biopharmaceutical manufacturing facilities that support emerging innovative processes and technologies, use state-of-the-art equipment, are energy efficient and sustainable, and meet regulatory requirements.
Relying on their many years of hands-on design and operations experience, the authors emphasize concepts and practical approaches toward design, construction, and operation of biomanufacturing facilities, including product-process-facility relationships, closed systems and single use equipment, aseptic manufacturing considerations, design of biocontainment facility and process based laboratory, and sustainability considerations, as well as an outlook on the facility of the future.
Provides guidelines for meeting licensing and regulatory requirements for biomanufacturing facilities in the U.S.A and WHO--especially in emerging global markets in India, China, Latin America, and the Asia/Pacific regions
Focuses on innovative design and equipment, to speed construction and time to market, increase energy efficiency, and reduce footprint, construction and operational costs, as well as the financial risks associated with construction of a new facility prior to the approval of the manufactured products by regulatory agencies
Includes many diagrams that clarify the design approach
Process Architecture in Biomanufacturing Facility Design is an ideal text for professionals involved in the design of facilities for manufacturing of biopharmaceuticals and vaccines, biotechnology, and life-science industry, including architects and designers of industrial facilities, construction, equipment vendors, and mechanical engineers. It is also recommended for university instructors, advanced undergraduates, and graduate students in architecture, industrial engineering, mechanical engineering, industrial design, and industrial interior design.
Автор: P. Agrarwal; A. Fiechter; C. Kleinstreuer; H.C. Li Название: Bioprocess Parameter Control ISBN: 3662152835 ISBN-13(EAN): 9783662152836 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: A.R. Moreira; Kimberlee K. Wallace Название: Computer and Information Science Applications in Bioprocess Engineering ISBN: 9401065640 ISBN-13(EAN): 9789401065641 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the NATO Advanced Study Institute on `Use of Computer and Informatic Systems in Bioprocess Engineering`, Ofir, Portugal, May 18-29, 1992
Автор: Ravindra Pogaku Название: Horizons in Bioprocess Engineering ISBN: 3030290689 ISBN-13(EAN): 9783030290689 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is divided into four parts that outline the use of science and technology for applications pertaining to chemical and bioprocess engineering. The book endeavors to help academia, researchers, and practitioners to use the principles and tools of Chemical and Bioprocess Engineering in a pertinent way, while attempting to point out the novel thoughts associated with the brain storming concepts encountered. As an example, the ability to use case studies appropriately is more important, to most practitioners.
This comprehensive and unique text presents a full overview of downstream processing useful for those new to the concept as well as professionals with experience in the area. The history and theoretical principles of Aqueous Two-Phase Systems (ATPS) are covered in depth. Information on ATPS characterization and application is included, and ATPS equilibria and system parameters that have significant effect on partition behavior are studied.
Aqueous Two-Phase Systems for Bioprocess Development for the Recovery of Biological Products addresses specific applications of ATPS for the recovery and partial purification of high molecular weight compounds such as proteins, nucleic acids and polysaccharides, particulate bioproducts such as cells and organelles and low molecular weight compounds. Non-conventional strategies involving ATPS such as affinity systems, continuous liquid-liquid fractionation stages and the recovery from plant extracts are presented. Economic analysis of the application of ATPS in comparison to other fractionation techniques, particularly liquid chromatography, is considered, as are opportunity and current trends in the ATPS research area.
Each chapter utilizes the contributors' experimental expertise in traditional and non-conventional ATPS strategies, as well as analysis of areas of opportunity and perspectives on the development and future applications of ATPS in both the lab and larger scale operations. The result is a thorough and singular overview of ATPS which has not been matched by any other text on the market.
Название: Bioprocess Engineering For A Green ISBN: 1138035971 ISBN-13(EAN): 9781138035973 Издательство: Taylor&Francis Рейтинг: Цена: 188850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book deals with bioprocess engineering, which encompasses the design and development of equipment and processes for the manufacturing of products such as food, pharmaceuticals, chemicals, polymers and paper from biological materials.
Автор: M. Berovic; B. Contreras; M. Dueser; N. Krieger; M Название: New Products and New Areas of Bioprocess Engineering ISBN: 3662147106 ISBN-13(EAN): 9783662147108 Издательство: Springer Рейтинг: Цена: 217680.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Luigi Salvay Название: Bioreactors: Animal Cell Culture Control for Bioprocess Engineering ISBN: 1681176955 ISBN-13(EAN): 9781681176956 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Bioreactor is a key device during in vitro animal cell culture. There are several types of bioreactors, including stirred-tank, airlift, hollow-fibre, and Rotary Cell Culture System (RCCS) designs. The stirred-tank bioreactor is one of the most commonly used types, and is used both for industrial applications and laboratory research. The RCCS, invented by NASA, is increasingly used in the area of tissue engineering for medical purposes. Important improvements have been made in the design of traditional bioreactors, and new types of bioreactor are also being developed such as Couette-Taylor bioreactor, multifunctional-membrane bioreactor, and shaking bioreactor. It provides an appropriate growth environment for the cells, enabling them to proliferate and become the final bio-product. Since animal cells are different from microbial cells in morphology, culture skill needed, and mechanical stimulation needed, the traditional microbial bioreactors are not suitable for the large-scale animal cell culture any more, and many new bioreactors are developed. Bioreactors play a key role in the field of biologics, where they are used for the production of recombinant therapeutic proteins by large-scale cultivation of animal cells. Work is also progressing on techniques to improve the performance of bioreactors, including perfusion culture, the use of microcarriers, and methods of suppressing apoptosis and of monitoring cell growth in real time. Given the demand for the production by animal cells for use in the growing number of clinical applications, further advances in bioreactor technology can be expected during the next few years. Bioreactors: Animal Cell Culture Control for Bioprocess Engineering presents the design, fabrication, and control of a new type of bioreactor meant especially for animal cell line culture. It reviews the bioreactors particularly designed for the animal cell culture, and addresses the mechanical loads on the cultured cells. Animal cell processes are primarily used for the production of proteins and viral vaccines of relatively high value. Recent advancements in animal cell bioreactor are reviewed. Most previous concerns about the potential difficulties in scaling-up animal cell processes have been alleviated by the developments in bioreactors.
Автор: Hu Название: Cell Culture Bioprocess Engineering ISBN: 1498762859 ISBN-13(EAN): 9781498762854 Издательство: Taylor&Francis Рейтинг: Цена: 122490.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This reference guide is designed for industrial practitioners of mammalian cell cultivation for the production of biologics. This work is a culmination of two decades of accumulated expertise, practical know-how and best practices in cell culture technology. The Second Edition consists of major updates to all relevant topics.
Автор: Liu, Shijie Название: Bioprocess Engineering: ISBN: 0444637834 ISBN-13(EAN): 9780444637833 Издательство: Elsevier Science Рейтинг: Цена: 142470.00 T Наличие на складе: Поставка под заказ. Описание: Bioprocess Engineering: Kinetics, Sustainability, and Reactor Design, Second Edition, provides a comprehensive resource on bioprocess kinetics, bioprocess systems, sustainability, and reaction engineering. Author Dr. Shijie Liu reviews the relevant fundamentals of chemical kinetics, batch and continuous reactors, biochemistry, microbiology, molecular biology, reaction engineering, and bioprocess systems engineering, also introducing key principles that enable bioprocess engineers to engage in analysis, optimization, and design with consistent control over biological and chemical transformations. . The quantitative treatment of bioprocesses is the central theme in this book, with more advanced techniques and applications being covered in depth. This updated edition reflects advances that are transforming the field, ranging from genetic sequencing, to new techniques for producing proteins from recombinant DNA, and from green chemistry, to process stability and sustainability. The book introduces techniques with broad applications, including the conversion of renewable biomass, the production of chemicals, materials, pharmaceuticals, biologics, and commodities, medical applications, such as tissue engineering and gene therapy, and solving critical environmental problems.
Автор: R. Aarts; M. Aynsley; J.E. Bailey; P.M. Doran; I.J Название: Bioprocess Design and Control ISBN: 3662149591 ISBN-13(EAN): 9783662149591 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Simpson Ricardo Название: Chemical and Bioprocess Engineering ISBN: 1461491258 ISBN-13(EAN): 9781461491255 Издательство: Springer Рейтинг: Цена: 56590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This introductory textbook covers all aspects chemical and bioprocess engineering, and provides a thorough grounding in the fundamentals. It features more than 400 proposed and solved exercises each classified by level of difficulty.
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