Practical Statistics for Pharmaceutical Analysis: With Minitab Applications, de Muth James E.
Автор: Watson David G. Название: Pharmaceutical Analysis. 5 ed ISBN: 0702078077 ISBN-13(EAN): 9780702078071 Издательство: Elsevier Science Рейтинг: Цена: 35370.00 T Наличие на складе: Есть Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes Two new chapters: Chapter 16 Methods used in the quality control of biotechnologically produced drugs Chapter 17 Electrochemical biosensors
Автор: James E. De Muth Название: Practical Statistics for Pharmaceutical Analysis ISBN: 3030339882 ISBN-13(EAN): 9783030339883 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This is an introductory statistics book designed to provide scientists with practical information needed to apply the most common statistical tests to laboratory research data. The book is designed to be practical and applicable, so only minimal information is devoted to theory or equations. Emphasis is placed on the underlying principles for effective data analysis and survey the statistical tests. It is of special value for scientists who have access to Minitab software. Examples are provides for all the statistical tests and explanation of the interpretation of these results presented with Minitab (similar to results for any common software package).The book is specifically designed to contribute to the AAPS series on advances in the pharmaceutical sciences. It benefits professional scientists or graduate students who have not had a formal statistics class, who had bad experiences in such classes, or who just fear/don’t understand statistics. Chapter 1 focuses on terminology and essential elements of statistical testing. Statistics is often complicated by synonyms and this chapter established the terms used in the book and how rudiments interact to create statistical tests. Chapter 2 discussed descriptive statistics that are used to organize and summarize sample results. Chapter 3 discussed basic assumptions of probability, characteristics of a normal distribution, alternative approaches for non-normal distributions and introduces the topic of making inferences about a larger population based on a small sample from that population. Chapter 4 discussed hypothesis testing where computer output is interpreted and decisions are made regarding statistical significance. This chapter also deasl with the determination of appropriate sample sizes. The next three chapters focus on tests that make decisions about a population base on a small subset of information. Chapter 5 looks at statistical tests that evaluate where a significant difference exists. In Chapter 6 the tests try to determine the extent and importance of relationships. In contrast to fifth chapter, Chapter 7 presents tests that evaluate the equivalence, not the difference between levels being tested. The last chapter deals with potential outlier or aberrant values and how to statistically determine if they should be removed from the sample data.Each statistical test presented includes an example problem with the resultant software output and how to interpret the results. Minimal time is spent on the mathematical calculations or theory. For those interested in the associated equations, supplemental figures are presented for each test with respective formulas. In addition, Appendix D presents the equations and proof for every output result for the various examples.Examples and results from the appropriate statistical results are displayed using Minitab 18?. In addition to the results, the required steps to analyze data using Minitab are presented with the examples for those having access to this software. Numerous other software packages are available, including based data analysis with Excel.
Автор: Mani Lakshminarayanan, Fanni Natanegara Название: Bayesian Applications in Pharmaceutical Development ISBN: 1138296767 ISBN-13(EAN): 9781138296763 Издательство: Taylor&Francis Рейтинг: Цена: 117390.00 T Наличие на складе: Невозможна поставка. Описание: This provides comprehensive coverage of Bayesian application across the span of drug development from discovery to clinical trial to manufacturing with practical examples as illustration.
Автор: Guy Wingate, Glaxo Smith Kline, Durham, UK Название: Pharmaceutical Computer Systems Validation ISBN: 1420088947 ISBN-13(EAN): 9781420088946 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Pharmaceutical Computer Systems Validation
Автор: Mikolaj Tosto Название: Chiroptical Spectroscopy: Fundamentals & Applications ISBN: 1681176904 ISBN-13(EAN): 9781681176901 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Chiroptical spectroscopy is one of the most developing areas of chiral analysis which role has been enhanced in recent years. There have been great advances in the fields of laboratory and astronomical spectroscopy. These have been equally matched by large-scale computations using stateof-the-art theoretical methods. The accurate atomic opacities that are available today play a great role in the field of biomedical research using nanotechnology. Spectroscopic techniques have been applied in virtually all technical fields of science and technology. Radio-frequency spectroscopy of nuclei in a magnetic field has been employed in a medical technique called magnetic resonance imaging (MRI) to visualize the internal soft tissue of the body with unprecedented resolution. This title provides an overview of the applicability range of chiroptical methods as a principle tool for chirality investigation, and typical applications of chiral coordination chemistry, such as circular dichroism (CD) spectroscopy is a spectroscopic technique where the CD of molecules is measured over a range of wavelengths. CD spectroscopy is used extensively to study chiral molecules of all types and sizes, but it is in the study of large biological molecules where it finds its most important applications. A primary use is in analysing the secondary structure or conformation of macromolecules, particularly proteins as secondary structure is sensitive to its environment, temperature or pH, circular dichroism can be used to observe how secondary structure changes with environmental conditions or on interaction with other molecules. Structural, kinetic and thermodynamic information about macromolecules can be derived from circular dichroism spectroscopy. Because of this sensitivity, the most accurate physical measurements have been frequency measurements. This book, Chiroptical Spectroscopy: Fundamentals and Applications, provides an introduction to the important methods of chiroptical spectroscopy in general, and circular dichroism in particular, which are increasingly important in all areas of chemistry, biochemistry, and structural biology. The book is to be intended a valuable tool for advanced graduate students along with researchers in academia and industry.
Название: Natural Polymers for Pharmaceutical Applications ISBN: 1771888458 ISBN-13(EAN): 9781771888455 Издательство: Taylor&Francis Рейтинг: Цена: 126580.00 T Наличие на складе: Нет в наличии. Описание: This new volume, Natural Polymers for Pharmaceutical Applications, Volume 1: Plant-Derived Polymers, presents some of the latest research on the applications of natural polymers in drug delivery and therapeutics for healthcare benefits.
Автор: Dykman, Lev A. Khlebtsov, Nikolai Название: Gold nanoparticles in biomedical applications ISBN: 113856074X ISBN-13(EAN): 9781138560741 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.
Автор: Anya M Hillery Название: Drug Delivery Fundamentals and Applications, Second Edition ISBN: 1482217716 ISBN-13(EAN): 9781482217711 Издательство: Taylor&Francis Рейтинг: Цена: 122490.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book provides a comprehensive introduction to advanced drug delivery and targeting, covering their principles, current applications, and potential future developments. This edition has been updated to reflect significant trends and cutting-edge advances that have occurred since the first edition was published. All the original chapters have been retained, but the material therein has been updated. Eight new chapters have been added that deal with entirely new technologies and approaches.
Features:
Offers a comprehensive introduction to the fundamental concepts and underlying scientific principles of drug delivery and targeting
Presents an in-depth analysis of the opportunities and obstacles afforded by the application of nanotechnologies for drug delivery and targeting
Includes a revised and expanded section on the major epithelial routes of drug delivery currently under investigation
Describes the most recent, emerging, and innovative technologies of drug delivery
Provides real-life examples of the clinical translation of drug delivery technologies through the use of case studies
Discusses the pertinent regulatory hurdles and safety issues of drug delivery and targeting systems--crucial considerations in order to achieve licensing approval for these new technologies
Автор: Chauhan, Abhay Singh Название: Pharmaceutical Applications Of Dendrimers ISBN: 0128145277 ISBN-13(EAN): 9780128145272 Издательство: Elsevier Science Рейтинг: Цена: 174050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Pharmaceutical Applications of Dendrimers explores the applications of dendrimers in the solubilization of hydrophobic active ingredients, drug delivery, gene delivery, imaging, diagnosis and photodynamic therapy. The book discusses the diagnostic applications of dendrimers, including their use as MRI contrast agents and in the imaging of diseased areas. In addition, the anti-inflammatory, antimicrobial and antiviral properties of PPI and PAMAM are also covered, along with a discussion on photosensitizers, such as rose Bengal and protoporphyrin IX that have been delivered using PAMAM and PPI dendrimers for the treatment of cancer.
This book is an important research reference for those who want to learn more about the development of dendrimer-based solutions for drug delivery.
Автор: Marchenko Olga V., Katenka Natallia V. Название: Quantitative Methods in Pharmaceutical Research and Development: Concepts and Applications ISBN: 3030485544 ISBN-13(EAN): 9783030485542 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This contributed volume presents an overview of concepts, methods, and applications used in several quantitative areas of drug research, development, and marketing.
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