Chronic Lung Diseases: Pathophysiology and Therapeutics, Rayees Sheikh, Din Inshah, Singh Gurdarshan

Автор: Gupta
Название: Anti-inflammatory Nutraceuticals and Chronic Diseases
ISBN: 3319413325 ISBN-13(EAN): 9783319413327
Издательство: Springer
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Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in various chronic diseases. Food and Drug Administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. This means that there is enormous potential for dietary agents that can modulate inflammatory pathways in humans. Leading experts describe the latest research on the role of anti-inflammatory nutraceuticals in preventing and treating chronic diseases.

Автор: Blaine
Название: Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance
ISBN: 3319433571 ISBN-13(EAN): 9783319433578
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the basic mechanisms of albuminuria, a particular highlight will be the focus on advanced imaging techniques such as intravital microscopy that have allowed a detailed “window” into albumin transit through the kidney. The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus and the proximal tubule and the pathophysiology of proteinuric diseases including minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis and diabetic nephropathy.

Автор: Albrecht Reichle
Название: Evolution-adjusted Tumor Pathophysiology:
ISBN: 9400797877 ISBN-13(EAN): 9789400797871
Издательство: Springer
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Цена: 149060.00 T
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Описание: Combined modularized therapies for metastatic cancer are pointing to central problems of communication among ‘systems participators’. A communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations constituting the tumor's normativity (inflammation, immune response etc.) represents the non-genomic counterpart of the tumor genome and should be additionally assessed during tumor staging. Evolution-adjusted tumor pathophysiology allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and personalizing tumor therapy. Combined modularized therapy, evolution-adjusted tumor pathophysiology, and ‘universal’ biomarkers concertedly address genetically based tumor heterogeneity.

Автор: Blaine Judith
Название: Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance
ISBN: 3319828010 ISBN-13(EAN): 9783319828015
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent work has begun to elucidate at the molecular level how albumin is handled by the kidney and how albuminuria develops in various proteinuric diseases including minimal change disease and focal segmental glomerulosclerosis. This volume provides a comprehensive overview of the renal handling of albumin – from basic mechanisms to the pathophysiology of proteinuric diseases. In describing the basic mechanisms of albuminuria, a particular highlight will be the focus on advanced imaging techniques such as intravital microscopy that have allowed a detailed “window” into albumin transit through the kidney. The volume will cover the epidemiological studies which show that albuminuria is a strong and independent marker of kidney disease progression and cardiovascular events, the molecular details of albumin handling in the kidney at the level of the glomerulus and the proximal tubule and the pathophysiology of proteinuric diseases including minimal change disease, membranous nephropathy, focal segmental glomerulosclerosis and diabetic nephropathy.

Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar
Название: Oxidative Stress in Lung Diseases: Volume 1
ISBN: 9811384150 ISBN-13(EAN): 9789811384158
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.

Автор: Chakraborti Sajal, Chakraborti Tapati, Das Salil Kumar
Название: Oxidative Stress in Lung Diseases: Volume 1
ISBN: 9811384126 ISBN-13(EAN): 9789811384127
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This first volume of the comprehensive, two-volume work on oxidative stress in lung disease introduces the molecular mechanisms, and the role of oxidants in the progression of different lung diseases. The lungs of humans and animals are under constant threat from oxidants from either endogenous (e.g. in situ metabolic reactions) or exogenous sources (e.g. air pollutants). Further, oxidative stress causes the oxidation of proteins, DNA and lipids, which in turn generates secondary metabolic products. The book consists of sections, each focusing on different aspects of oxidant-mediated lung diseases. As such it is a unique reference resource for postgraduate students, biomedical researchers and also for the clinicians who are interested in studying and understanding oxidant-mediated lung diseases. The second volume will incorporate other aspects of oxidant-mediated lung diseases, including prevention and therapeutics.

Автор: Martin C. Woodle; Gerrit Storm
Название: Long Circulating Liposomes: Old Drugs, New Therapeutics
ISBN: 3662221179 ISBN-13(EAN): 9783662221174
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides an up-to-date evaluation of clinical aspects of newly available "long-circulating liposome" formulations. It provides the practicing clinician - in particular, oncologists and critical care infectious disease physicians - with the tools needed to use these new formulations towards the best outcome for the patient.

Автор: Joseph G. Cory; A. Szentivanyi
Название: Cancer Biology and Therapeutics
ISBN: 0306425440 ISBN-13(EAN): 9780306425448
Издательство: Springer
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Цена: 186340.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These topics ranged from the biochemistry of the cancer cell to the design of antineoplastic agents, through tumor cell heterogeneity, treatment of ltuman neoplasms to immunological aspects of cancer biology and tr~atment.

Автор: Hae Won Kim; A. Gerson Greenburg
Название: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics
ISBN: 3662508079 ISBN-13(EAN): 9783662508077
Издательство: Springer
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Цена: 121110.00 T
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Описание: Currently, hemoglobin (Hb)-based oxygen carriers (HBOCs) are leading candidates as red blood cell substitutes. In addition, HBOCs are also potential oxygen therapeutics for treatment of patients with critical ischemic conditions due to atherosclerosis, diabetes and other conditions. This book will provide readers a comprehensive review of topics involved in the HBOC development. It focusses on current products and clinical applications as well as on emerging technologies and future prospects.

Автор: Hae Won Kim; A. Gerson Greenburg
Название: Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics
ISBN: 3642407161 ISBN-13(EAN): 9783642407161
Издательство: Springer
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Цена: 167700.00 T
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Описание: With details of recent progress in HBOC research along with emerging products, this in-depth treatment surveys the scientific and clinical fundamentals. It evaluates the literature on safety and efficacy and predicts the most likely forthcoming advances.

Автор: Kenneth A. Howard
Название: RNA Interference from Biology to Therapeutics
ISBN: 1489993193 ISBN-13(EAN): 9781489993199
Издательство: Springer
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Цена: 191550.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume addresses the role of different RNAi molecules in cellular processes as rational for diagnostic and therapeutic approaches. It covers RNAi therapeutic design to optimize siRNA potency and reduce off-target effects.

Автор: Yosef Yarden; Moshe Elkabets
Название: Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways
ISBN: 3319679309 ISBN-13(EAN): 9783319679303
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression.