Cafer's Psychopharmacology is an essential series for any prescriber of psychiatric medication. Filled with pictures, this book makes complex concepts easy to understand and provides tools for remembering more than you thought possible.
To help you match trade names with generic names of 39 medications, this book features mascots akin to the Xyzal "Wise Owl" and Myrbetriq Bladder characters. Each medication's mascot is incorporated into a visual-mnemonic framework designed for recollection of pharmacokinetic interactions.
For instance, CYP2C19 substrates are represented as flowers with CYP2C19 inhibitors as watering cans to make the flowers grow. CYP1A2 substrates are trees to be chopped down by axes (CYP1A2 inducers). Lithium is a battery and anything that interferes with its renal excretion is depicted as a battery charger.
In addition to lithium, this book includes all of the major antiepileptic drugs (encompassing all of the mood stabilizers other than lithium) and all available benzodiazepines (about half of which are FDA approved for treatment of seizure disorders).
Автор: Speck-Planche, Alejandro Название: Multi-Scale Approaches in Drug Discovery ISBN: 0081011296 ISBN-13(EAN): 9780081011294 Издательство: Elsevier Science Рейтинг: Цена: 185270.00 T Наличие на складе: Поставка под заказ. Описание:
Drug discovery is an expensive, time-consuming process and the modern drug discovery community is constantly challenged not only with discovering novel bioactive agents to combat resistance from known diseases and fight against new ones, but to do so in a way that is economically effective. Advances in both experimental and theoretical/computational methods envisage that the greatest challenges in drug discovery can be most successfully addressed by using a multi-scale approach, drawing on the specialties of a whole host of different disciplines. Multi-Scale Approaches to Drug Discovery furnishes chemists with the detail they need to identify drug leads with the highest potential before isolating and synthesizing them to produce effective drugs with greater swiftness than classical methods may allow. This significantly speeds up the search for more efficient therapeutic agents.
After an introduction to multi-scale approaches outlining the need for and benefits of their use, the book goes on to explore a range of useful techniques and research areas, and their potential applications to this process. Profiling drug binding by thermodynamics, machine learning for predicting enzyme sub-classes, and multitasking models for computer-aided design and virtual compound screening are discussed, before the book goes on to review Alkaloid Menispermaceae leads, natural chemotherapeutic agents and methods for speeding up the design and virtual screening of therapeutic peptides. Flavonoids as multi-target compounds are then explored, before the book concludes with a review of Quasi-SMILES as a novel tool.
Collecting together reviews and original research contributions written by leading experts in the field, Multi-Scale Approaches to Drug Discovery highlights cutting-edge approaches and practical examples of their implementation for those involved in the drug discovery process at many different levels. Using the combined knowledge of medicinal, computational, pharmaceutical and bio- chemists, it aims to support growth in the multi-scale approach to promote greater success in the development of new drugs.
Автор: Patwardhan, Bhushan Название: Innovative Approaches in Drug Discovery ISBN: 0128018143 ISBN-13(EAN): 9780128018149 Издательство: Elsevier Science Рейтинг: Цена: 74100.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Despite considerable technological advances, the pharmaceutical industry is experiencing a severe innovation deficit, especially in the discovery of new drugs. Innovative Approaches in Drug Discovery: Ethnopharmacology, Systems Biology and Holistic Targeting provides a critical review and analysis of health, disease and medicine, and explores possible reasons behind the present crisis in drug discovery. The authors illustrate the benefits of systems biology and pharmacogenomics approaches, and advocate the expansion from disease-centric discovery to person-centric therapeutics involving holistic, multi-target, whole systems approaches. This book lays a path for reigniting pharmaceutical innovation through a disciplined reemergence of pharmacognosy, embracing open innovation models and collaborative, trusted public-private partnerships. With unprecedented advances made in the development of biomedically-relevant tools and technologies, the need is great and the time is nowfor a renewed commitment towards expanding the repertoire of medicines.a By incorporating real-life examples and state-of-the-art reviews, this book provides valuable insights into the discovery and development strategies for professionals, academicians, and students in the pharmaceutical sciences.
Analyzes the reasons behind historical drug failures to provide valuable insights on lessons learned
Uses current scientific research to promote learning from traditional knowledge systems and through the integration of traditional and western medicines
Discusses advances in technologies and systems biology to support the transition from formulation discovery to therapeutic discovery
Автор: Wang Название: Predictive ADMET: Integrated Approaches in Drug Discovery and Development ISBN: 1118299922 ISBN-13(EAN): 9781118299920 Издательство: Wiley Рейтинг: Цена: 142510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: By guiding in the application of techniques and tools for predicting ADMET outcomes in drug candidates, Predictive ADMET offers a road map for drug discovery scientists to generate effective and safe drugs for unmet medical needs.
Автор: Adejare, Adeboye Название: Drug Discovery Approaches for the Treatment of Neurodegenerative ISBN: 0128028106 ISBN-13(EAN): 9780128028100 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Drug Discovery Approaches for the Treatment of Neurodegenerative Disorders: Alzheimer's Disease examines the drug discovery process for neurodegenerative diseases by focusing specifically on Alzheimer's Disease and illustrating the paradigm necessary to ensure future research and treatment success.
The book explores diagnosis, epidemiology, drug discovery strategies, current therapeutics, and much more to provide a holistic approach to the discovery, development, and treatment of Alzheimer's Disease. Through its coverage of the latest research in targeted drug design, preclinical studies, and mouse and rat models, the book is a must-have resource for all pharmaceutical scientists, pharmacologists, neuroscientists, and clinical researchers working in this area. It illustrates why these drugs tend to fail at the clinical stage, and examines Alzheimer's Disease within the overall context of improving the drug discovery process for the treatment of other neurodegenerative disorders.
Автор: Asadi-Pooya Ali A., Sperling Michael R. Название: Antiepileptic Drugs: A Clinician`s Manual ISBN: 0190214961 ISBN-13(EAN): 9780190214968 Издательство: Oxford Academ Рейтинг: Цена: 55970.00 T Наличие на складе: Поставка под заказ. Описание: This concise handbook provides practical, up-to-date clinical guidance on effective selection, prescription, and usage of antiepileptic drugs for patients with epilepsy in various medical conditions and in a variety of clinical contexts. This text discusses choosing drugs when faced with various medical comorbidities; how to correctly prescribe, titrate, and taper drugs; how to monitor drug efficacy and side effects; how to diagnose and manage toxicity; how antiepileptic drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include � A brief formal discussion of the basic pharmacology of each antiepileptic drug, with an emphasis on how to select and use anti-epileptic drugs in a variety of clinical contexts. � Discussions of antiepileptic drugs approved for epilepsy since 2009. � New research about already existing antiepileptic drugs. � References for further reading that are oriented toward utility in clinical practice. Antiepileptic Drugs: A Clinician's Manual fills an unmet need as a practical, patient-oriented reference and leads to improved patient care. Supported by practical, clinical knowledge and experience, this is the perfect guide for physicians looking to ensure safe practices in antiepileptic drug therapy.
Автор: Talevi Название: Antiepileptic Drug Discovery ISBN: 1493963538 ISBN-13(EAN): 9781493963539 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory.
Authoritative and practical, Antiepileptic Drug Discovery: Novel Approaches aims to provide medicinal chemists, pharmacologists, and other researchers with the tools need to further explore the study of pharmacoresistant epilepsy and the discovery of new antiepileptic drugs.
Автор: Hans-Hasso Frey; D. Janz Название: Antiepileptic Drugs ISBN: 3642695205 ISBN-13(EAN): 9783642695209 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: By Arun Garg, By Ram Atma Bansal Название: Antiepileptic Drugs ISBN: 9388958241 ISBN-13(EAN): 9789388958240 Издательство: JayPee Brothers India Рейтинг: Цена: 47650.00 T Наличие на складе: Невозможна поставка. Описание:
Epilepsy is a common condition that affects the brain and causes frequent seizures. Seizures are bursts of electrical activity in the brain that temporarily affect how it works. They can cause a wide range of symptoms. Epilepsy can start at any age, but usually starts either in childhood or in people over 60.
This book is a comprehensive guide to the appropriate selection and usage of antiepileptic drugs (AEDs).
Beginning with historical and pharmacological aspects, the next chapters examine older, newer and third generation antiepileptic drugs, highlighting key differences between each type.
The following sections cover the use of AEDs amongst different sectors of the population – children, geriatrics and those with comorbidities such as pregnancy and systemic disorders.
The book concludes with discussion on drug monitoring and management of status epilepticus (a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. It is a life-threatening medical emergency particularly if treatment is delayed).
Presented in a step by step format, the text is further enhanced by algorithms, tables and diagrams to assist understanding.
Key points
Comprehensive guide to selection and usage of antiepileptic drugs (AEDs)
Covers AED use amongst different sectors of the population
Compares older, newer and third generation AEDs
Highly illustrated with algorithms, tables and diagrams
Автор: Patsalos Philip Название: Epilepsy Prescriber`s Guide to Antiepileptic Drugs ISBN: 1108453201 ISBN-13(EAN): 9781108453202 Издательство: Cambridge Academ Рейтинг: Цена: 61240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This fully updated book is an authoritative reference guide for the spectrum of diverse clinicians and allied health professionals who prescribe antiepileptic drugs in contemporary clinical practice. It includes clear information on thirty-five antiepileptic drugs, including newly-approved drug brivaracetam, and is essential for quick reference reading.
Автор: M.J. Eadie; F. Vajda Название: Antiepileptic Drugs ISBN: 3642642446 ISBN-13(EAN): 9783642642449 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Pohlmann-Eden, Bernd; Steinhoff, Bernhard J. Название: Understanding Antiepileptic Drugs ISBN: 0199358915 ISBN-13(EAN): 9780199358915 Издательство: Oxford Academ Рейтинг: Цена: 19530.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Written by two world experts, Understanding Antiepileptic Drugs describes the profiles of all current antiepileptic drugs comprehensively with all side effects. Understandable and well organized this book is unique in its kind and crucial for both patients and health cafe professionals dealing with epilepsy.
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