Estrogens and Memory: Basic Research and Clinical Implications, Frick Karyn M.
Автор: D.W. Pfaff Название: Estrogens and Brain Function ISBN: 1461380863 ISBN-13(EAN): 9781461380863 Издательство: Springer Рейтинг: Цена: 81050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Eric Kandel and his colleagues have provided us with the most exciting contemporary approach to the conceptualization and study of cellular mechanisms for behavior.
Автор: Vito J Thompson, Adrion E Watson Название: Estrogens: Biochemistry, Therapeutic Uses & Physiological Effects ISBN: 1620817470 ISBN-13(EAN): 9781620817476 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: Beginning with medieval European embroideries and tapestries, this book includes works from the United States, Canada, Latin America, Asia, the Middle and Near East, and Central Asia. It examines the ways in which women around the world have recorded the impact of war on their lives using traditional fabric art forms of knitting, sewing, quilting, embroidery, weaving, basketry and rug making.
Автор: George G Chen Название: Estrogen Receptors: Structure, Functions and Clinical Aspects ISBN: 1536182281 ISBN-13(EAN): 9781536182286 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: This 8-chapter book is written by experts from China, Mexico, Portugal, United Kingdom and the United States of America. The book is focused on estrogen receptor structure, functions and clinical significance. Though we are unable to address all aspects of the estrogen receptors, we have analysed and discussed estrogen receptors or their isoforms in some major estrogen receptor-related disorders including cancers, endocrine diseases, respiratory diseases and obesity. The information provided by this book should aid our understanding the role of estrogen receptors in human diseases. This book will be of great value not only for clinicians interested in estrogen receptor-related diseases but also for basic scientists working in the field of estrogen receptors.
Автор: Juan Pedro Martinez-Barbera; Cynthia Lilian Andoni Название: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma ISBN: 3319847708 ISBN-13(EAN): 9783319847702 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This astute volume brings together the latest expert research on adamantinomatous craniopharyngiomas (ACPs). ACPs are histologically benign but clinically aggressive tumors exhibiting a high propensity for local invasion into the hypothalamus, optic and vascular structures. These tumors, as well as the current treatments, may result in pan-hypopituitarism, diabetes insipidus, morbid obesity followed by type II diabetes mellitus, blindness, as well as serious behavioral and psychosocial impairments. Exploring in detail advances in both the understanding of tumor biology as well as clinical advances in patient management are explored in detail, this book will also look towards potential new treatment approaches.
Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma is the first book compiling all current research on ACPs. Mouse and human studies have unequivocally demonstrated that mutations in CTNNB1 encoding -catenin underlie the etiology of the majority, if not all ACP tumors. Genetic studies in mice have shown that ACPs are tumors of the pituitary gland and not of the hypothalamus as previously thought, and are derived from Rathke’s pouch precursors. In addition, a role for tissue-specific adult pituitary stem cells has been revealed as causative of ACP. Together, these studies have provided novel insights into the molecular and cellular etiology as well as the pathogenesis of human ACP. Finally, this volume covers new treatment approaches that have been shown to be effective both in reducing ACP burden as well as reducing the morbidity associated with therapy.
Автор: Kailash N Pandey Название: Natriuretic Peptides: Physiology, Molecular Biology & Clinical Implications ISBN: 1633210804 ISBN-13(EAN): 9781633210806 Издательство: Nova Science Рейтинг: Цена: 276660.00 T Наличие на складе: Невозможна поставка. Описание: This book provides the current knowledge and recent developments to navigate cellular, molecular, and clinical aspects of natriuretic peptides and their receptors in health and disease. State-of-the-art technology in cell and molecular biology has been applied to delineate the expression, function, and regulation of natriuretic peptides and their receptors both in vitro and in vivo model systems. Transgenic and gene-targeted mouse models have clearly demonstrated that the absence of functional natriuretic peptides and/or their cognate receptors cannot only raise blood pressure but also cause severe hypertensive heart, similar to what is seen in untreated human hypertensive patients. The genetically engineered mouse models have been useful to reveal not only the actual functions of the genes for natriuretic peptides and their receptors, but more critically their modifying interactions with other genes. This book presents a comprehensive look at the past developments, current status, and future prospects of the natriuretic peptides and their receptor systems in bedside diagnosis, treatments, and therapeutic advancements. The book comprises of fourteen chapters from eminent scientists in their area of research expertise, and presents a wide range of reviews spanning the research works done on the natriuretic peptides and their receptors. Each chapter provides a comprehensive summary covering the aspects of physiology, molecular biology, and clinical implication of the accomplished experimental findings and future perspectives of research to be performed in this vital and important cardiovascular field. It is expected that this book will provide readers a focused overview of the status and perspectives of the natriuretic peptides and their receptors from the past accomplishments to exciting future investigations.
Автор: Juan Pedro Martinez-Barbera; Cynthia Lilian Andoni Название: Basic Research and Clinical Aspects of Adamantinomatous Craniopharyngioma ISBN: 3319518887 ISBN-13(EAN): 9783319518886 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Pathogenesis of human ACP.- Transcriptomic and Genomic Analyses of Human Craniopharyngioma.- Genetically Modified Mouse Models of Adamantinomatous Craniopharyngioma.- Clinical Diagnosis of Human ACP.- Endocrine Deficits in Patients with Human Craniopharyngioma.- Obesity and metabolic disturbances in Adamantinomatous Craniopharyngioma Patients.- Radiology and Radiotherapy of Craniopharyngioma.- Surgical Treatment of Human ACP.- Intracystic Administration of Interferon-Alpha for Reduction of Cystic Tumour Burden.- Long-term Management and Clinical Trials in Adamantinomatous Craniopharyngioma
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