Автор: Arne Schousboe; Ursula Sonnewald Название: The Glutamate/GABA-Glutamine Cycle ISBN: 3319450948 ISBN-13(EAN): 9783319450940 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Fundamental biochemical studies of basic brain metabolism focusing on the neuroactive amino acids glutamate and GABA combined with the seminal observation that one of the key enzymes, glutamine synthetase is localized in astroglial cells but not in neurons resulted in the formulation of the term “The Glutamate-Glutamine Cycle.” In this cycle glutamate released from neurons is taken up by surrounding astrocytes, amidated by the action of glutamine synthetase to glutamine which can be transferred back to the neurons. The conversion of glutamate to glutamine is like a stealth technology, hiding the glutamate molecule which would be highly toxic to neurons due to its excitotoxic action. This series of reactions require the concerted and precise interaction of a number of enzymes and plasma membrane transporters, and this volume provides in-depth descriptions of these processes. Obviously such a series of complicated reactions may well be prone to malfunction and therefore neurological diseases are likely to be associated with such malfunction of the enzymes and transporters involved in the cycle. These aspects are also discussed in several chapters of the book.
A number of leading experts in neuroscience including intermediary metabolism, enzymology and transporter physiology have contributed to this book which provides comprehensive discussions of these different aspects of the functional importance of the glutamate-glutamine cycle coupling homeostasis of glutamatergic, excitatory neurotransmission to basic aspects of brain energy metabolism. This book will be of particular importance for students as well as professionals interested in these fundamental processes involved in brain function and dysfunction.
Автор: Mike Ludwig Название: Dendritic Neurotransmitter Release ISBN: 1461498384 ISBN-13(EAN): 9781461498384 Издательство: Springer Рейтинг: Цена: 163040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The transmission of the nervous impulse is always from the dendritic branches and the cell body to the axon or functional process. In some systems, dendritic transmitter release is part independent of secretion from axon terminal signifying a selective control of the dendritic compartment.
Автор: Mieczyslaw Pokorski Название: Neurotransmitter Interactions and Cognitive Function ISBN: 331910005X ISBN-13(EAN): 9783319100050 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A host of neurotransmitters and neuroactive substances underlies respiratory regulation in health and disease. The centerpiece of investigations regarding adaptation to hypoxia and sensorial perception has been the dopaminergic system. It is now clear that a complex interaction among various neuroactive substances, rather than a single one, forms the basis of respiratory changes. The research on neurotransmitter interactions provides the knowledge of how the brain functions and a new level of understanding of mind-to-body connection, which opens up avenues for novel therapeutic interventions.
Автор: Shozo Kito Название: Neurotransmitter Receptors ISBN: 1468448072 ISBN-13(EAN): 9781468448078 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This meeting was held commemorating Dr. Kito`s 10th Anniversary as Professor of the Third Department of Internal Medicine, Hiroshima University School of Medicine. In 1973, he became Professor of the Third Department of Internal Medicine, Hiroshima University School of Medicine.
Автор: Zhao-Wen Wang Название: Molecular Mechanisms of Neurotransmitter Release ISBN: 1627038841 ISBN-13(EAN): 9781627038843 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The aim of Molecular Mechanisms of Neurotransmitter Release is to provide up-to-date, in-depth coverage of essentially all major mole- lar mechanisms of neurotransmitter release.
Автор: Alan A. Boulton; Glen B. Baker; Augusto V. Juorio Название: Drugs as Tools in Neurotransmitter Research ISBN: 1489941053 ISBN-13(EAN): 9781489941053 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Maarten E. A. Reith Название: Neurotransmitter Transporters ISBN: 1617372676 ISBN-13(EAN): 9781617372674 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Richard C. Rayne Название: Neurotransmitter Methods ISBN: 1617370231 ISBN-13(EAN): 9781617370236 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Neurotransmitter Methods is intended as a bench-side companion for researchers who seek to identify, locaHze, or measure neurotransmitters and/or to identify sites of neurotransmitter action.
Автор: Alan A. Boulton; Glen B. Baker; Peter H. Yu Название: Neurotransmitter Enzymes ISBN: 1489941304 ISBN-13(EAN): 9781489941305 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are provided for all types of ligand-receptor binding, including chapters on general principles, drug discovery and development, and a most useful-appendix on computer programs for Scatchard, nonlinear, and competitive d- placement analyses.
Автор: Mieczyslaw Pokorski Название: Neurotransmitter Interactions and Cognitive Function ISBN: 3319363700 ISBN-13(EAN): 9783319363707 Издательство: Springer Рейтинг: Цена: 95770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A host of neurotransmitters and neuroactive substances underlies respiratory regulation in health and disease. It is now clear that a complex interaction among various neuroactive substances, rather than a single one, forms the basis of respiratory changes.
Автор: B?nisch Название: Neurotransmitter Transporters ISBN: 1493937634 ISBN-13(EAN): 9781493937639 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The volume aims at providing an overview of cutting-edge methods and protocols used in neuroscience and neurological research. Neurotransmitter Transporters: Investigative Methods will be of interest to scientists, graduate students, and advanced undergraduates who seek an overview of methods and protocols in this field of neuroscience. It will also be of interest to physicians who are carrying out imaging and postmortem studies of neurotransmitter transporters in the human brain. Written for the popular Neuromethods series, chapters include the kind of detail and key implementation advice that ensures successful results in the laboratory.Authoritative and practical, Neurotransmitter Transporters: Investigative Methods aims to ensure successful results in thefurther study of this vital field.
Автор: H. F. Bradford Название: Neurotransmitter Interaction and Compartmentation ISBN: 146841142X ISBN-13(EAN): 9781468411423 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The NATO Advanced Study Institute held in the Hotel Metropole Llandrindod Wells, Powys, Wales from July 26th to August 4th 1981 provided an excellent platform for presentation and appraisal of our current knowledge of neurotransmitter systems.
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