Pi3k-Mtor in Cancer and Cancer Therapy, Dey Nandini, De Pradip, Leyland-Jones Brian
Автор: Karp Daniel D Название: Handbook of Targeted Cancer Therapy and Immunotherapy ISBN: 1496389131 ISBN-13(EAN): 9781496389138 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 53190.00 T Наличие на складе: Нет в наличии. Описание: A must-have resource for oncologists, researchers, and other cancer care professionals! This comprehensive yet concise reference includes clinical trial results of more than 190 targeted therapy and immunotherapy agents. Immunotherapy trial results expanded Tumor immunology section added Recent landmark trial results incorporated FDA approvals highlighted Approach clinical challenges from any direction. Chapters organized by tumor type, pathway, and drug name. Find information quickly and easily, using a color-coded, intuitive format. Small enough to fit in your lab coat pocket. Or, download the eBook to your smartphone or other device for even more convenient referencing. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Автор: Pelengaris Название: The Molecular Biology of Cancer, 2nd Edition ISBN: 1118008812 ISBN-13(EAN): 9781118008812 Издательство: Wiley Рейтинг: Цена: 98150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Molecular Biology of Cancer, Stella Pelengaris & Michael Khan This capturing, comprehensive text, extensively revised and updated for its second edition, provides a detailed overview of the molecular mechanisms underpinning the development of cancer and its treatment.
Автор: Weinberg Robert A Название: Biology of Cancer 2 ed. ISBN: 0815345283 ISBN-13(EAN): 9780815345282 Издательство: Wiley Рейтинг: Цена: 73920.00 T Наличие на складе: Невозможна поставка. Описание: The definitive text on cancer biology, thoroughly updated.
Автор: Vincent T. DeVita, Theodore S. Lawrence, Steven A. Название: Cancer: Principles and Practice of Oncology Primer of Molecular Biology in Cancer ISBN: 1975149114 ISBN-13(EAN): 9781975149116 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 91520.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Recent scientific advances have revolutionized cancer research and practice, creating a body of molecular biology information that is important to research scientists and clinical oncologists alike. Cancer: Principles and Practice of Oncology: Primer of the Molecular Biology of Cancer, 3rd Edition, keeps you up to date with all that’s new in this rapidly changing field. Derived from DeVita, Hellman, and Rosenberg’s Cancer: Principles and Practice of Oncology – widely regarded as the definitive clinical reference in oncology – the third edition of this popular Primer provides a single-volume, highly focused reference on every important frontier in the molecular biology of cancer.
Compiles the knowledge and experience of leading scientists and clinicians in the field.
Provides separate chapters on each of the 18 most common cancer types, with state-of-the-art information on how molecular biology advances are impacting clinical practice.
Includes a thorough chapter on genetic counseling and genetic testing to help you navigate the challenges and ethical dilemmas of cancer genetics.
Covers key topics such as Hallmarks of Cancer, Precision Medicine in Oncology, Cancer Immunotherapy, Pharmacogenomics, and many more.
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Read directly on your preferred device(s), such as computer, tablet, or smartphone.
Easily convert to audiobook, powering your content with natural language text-to-speech.
Автор: Devita, Vincent T., Jr., Md Rosenberg, Steven A. L Название: Devita, Hellman, and Rosenberg`s cancer: principles & practice of oncology. 11 ed ISBN: 1496394631 ISBN-13(EAN): 9781496394637 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 318030.00 T Наличие на складе: Невозможна поставка. Описание: Now updated online for the life of the edition, DeVita, Hellman, and Rosenberg's Cancer: Principles & Practice of Oncology, 11th Edition keeps you up to date in this fast-changing field. Every quarter, your eBook will be updated with late-breaking developments in oncology, including new drugs, clinical trials, and more. This unique, continually updated reference remains the gold standard reference in the field with: A focus on immunotherapy throughout and new chapters on precision oncology and the microbiome. Guidance on managing every type of cancer, while incorporating recent treatment advances. The most effective strategies for managing every type of cancer by stage of presentation. Balanced, multidisciplinary advice from a surgeon, a medical oncologist, and a radiation oncologist. Important related topics such as cancer screening and prevention, palliative care, supportive oncology, and quality of life issues. Enhance Your eBook Reading Experience: Read directly on your preferred device(s), such as computer, tablet, or smartphone. Easily convert to audiobook, powering your content with natural language text-to-speech.
Автор: Grumezescu, Alexandru Mih Название: Nanostructures for Cancer Therapy ISBN: 0323461441 ISBN-13(EAN): 9780323461443 Издательство: Elsevier Science Рейтинг: Цена: 151590.00 T Наличие на складе: Нет в наличии. Описание:
Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics.
In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents.
The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer.
Автор: Mahul B. Amin; Stephen B. Edge; Frederick L. Green Название: AJCC Cancer Staging Manual ISBN: 3319406175 ISBN-13(EAN): 9783319406176 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This fully revised and updated seventh edition of the bible on cancer diagnosis brings together all currently available information on staging of cancer at various anatomic sites and includes newly acquired knowledge on the etiology and pathology of cancer.
Автор: Vitaly A. Polunovsky; Peter J. Houghton Название: mTOR Pathway and mTOR Inhibitors in Cancer Therapy ISBN: 1617796948 ISBN-13(EAN): 9781617796944 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The target of rapamycin (TOR) was rst identi ed in Saccharomyces cerevisiae and subsequently in mammals (mTOR) as a conserved atypical serine/threonine kinase. Rapamycin was isolated as a product of the soil bacteria Streptomyces hygroscopicus, identi ed in a soil sample taken from the island of Rapa Nui (Easter Island).
Автор: Monica Mita; Alain Mita; Eric K. Rowinsky Название: mTOR Inhibition for Cancer Therapy: Past, Present and Future ISBN: 2817805577 ISBN-13(EAN): 9782817805573 Издательство: Springer Рейтинг: Цена: 83850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes the challenges involved in developing mTOR inhibitors for cancer treatment, starting with an in-depth examination of their molecular mechanism of action, with emphasis on the class side-effects, efficacy and mechanisms of resistance, as well as on promising novel directions for their development, including novel compounds and rational combinations with other anti-neoplastic drugs. Over the last 10 years, inhibitors of mTOR have emerged as a major class of anticancer drugs. Two rapamycin analogs are currently approved for the treatment of renal cell carcinoma, and it is estimated that a variety of other tumor types could benefit from mTOR inhibition, with numerous clinical trials (including pivotal registration trials) already underway. Second-generation small-molecule inhibitors of the pathway have also shown promise in terms of their superior tolerability and efficacy and are undergoing extensive clinical evaluation, with an estimated 30+ compounds currently under evaluation.
Автор: Mtui, Estomih Gruener, Gregory Dockery, Peter Название: Fitzgerald`s Clinical Neuroanatomy and Neuroscience, 7e Elsevier 2016 ISBN: 0702058327 ISBN-13(EAN): 9780702058325 Издательство: Elsevier Science Рейтинг: Цена: 53050.00 T Наличие на складе: Невозможна поставка. Описание: Preceded by: Clinical neuroanatomy and neuroscience / M.J. Turlough FitzGerald, Gregory Gruener, Estomih Mtui. 6th ed. 2012.
Автор: Dey Название: PI3K-mTOR in Cancer and Cancer Therapy ISBN: 3319342096 ISBN-13(EAN): 9783319342092 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In the post human-genome project era, cancer specific genomic maps are redesigning tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control beneficial pathways. The overwhelming power of genomics and proteomics has enlightened researchers about the fact that the PI3K-mTOR pathway is the most commonly up-regulated signal transduction pathway in various cancers, either by virtue of its activation downstream of many cell surface growth factor receptors or by virtue of its collateral and compensatory circuitry with RAS-MAPK pathway. Oncogenic signaling in the majority of solid tumors is sustained via the PI3K-AKT-mTOR pathway. Because of its prominent role in many cancer types, the PI3K-mTOR pathway has become a major therapeutic target. The volume includes two complementary parts which address the problem of etiology and disease progression and is intended to portray the very basic mechanisms of the PI3K-AKT-mTOR signaling pathway’s involvement in various facets of the cancer, including stem cell renewal, cell metabolism, angiogenesis, genetic instability, and drug resistance. Significant progress has been made in recent years elucidating the molecular mechanism of cancer cell proliferation, angiogenesis, and drug-resistance in relation to the PI3K-mTOR pathway and this volume provides an in-depth overview of recent developments made in this area.?
Автор: Mendelsohn, John Название: The Molecular Basis of Cancer ISBN: 1455740667 ISBN-13(EAN): 9781455740666 Издательство: Elsevier Science Рейтинг: Цена: 167300.00 T Наличие на складе: Нет в наличии. Описание: Arms you with the advances in the battle against cancer. This title explores the scientific basis for our current understanding of malignant transformation and the pathogenesis and treatment of this disease.
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