Ketamine: From Abused Drug to Rapid-Acting Antidepressant, Hashimoto Kenji, Ide Soichiro, Ikeda Kazutaka
Автор: Duman, Ronald Название: Rapid Acting Antidepressants,89 ISBN: 0128201894 ISBN-13(EAN): 9780128201893 Издательство: Elsevier Science Рейтинг: Цена: 213350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The Advances in Pharmacology series presents a variety of chapters from the best authors in the field.
Автор: Hashimoto Kenji, Ide Soichiro, Ikeda Kazutaka Название: Ketamine: From Abused Drug to Rapid-Acting Antidepressant ISBN: 9811529019 ISBN-13(EAN): 9789811529016 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents the latest data from basic research and clinical trials supporting the effectiveness of ketamine as a treatment for depression, bipolar disorder, and suicidal behavior, setting these positive findings within the context of the serious problem of ketamine abuse.
Автор: Leland A. McBride Название: Ketamine: History, Uses and Health Effects ISBN: 1536167312 ISBN-13(EAN): 9781536167313 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: Ketamine: History, Uses and Health Effects first compares the pathology of the urinary system in ketamin- treated mice with those treated by Uncaria rhynchophylla plus e and Gouteng-treated mice. This compilation goes on to assess the current literature regarding the effectiveness and the adverse effects of ketamine in burn pain management, coming to conclusions about its potential clinical use for burns among children and adults. Following this, the authors provide cellular, and molecular evidence regarding the ketamine effects in clinical and preclinical models of major depressive disorder. A critical review on ketamine and other phencyclidine analogues, namely the most consumed metoxethamine, 3-methoxyphencyclidine and 4-methoxyphencyclidine, is also provided. Lastly, a new approach for the on-site detection and quantification of ketamine based on the isolation of its product of reaction with gold bromide onto nylon filters and subsequent digital color analysis is presented.
Автор: Hyde, Dr Stephen J Название: Ketamine for depression ISBN: 1503509559 ISBN-13(EAN): 9781503509559 Издательство: Неизвестно Рейтинг: Цена: 55610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: "
Given the unacceptably high rates of suffering, disability and premature death experienced by people with treatment-resistant depression and the surprisingly low rates of problems arising from the use of ketamine to treat the disorder, this is a therapy that all patients and their doctors should be discussing.
This book summarises the research that has been carried out into ketamine for the treatment of depression over the past 15 years and, most importantly, describes different ways of using ketamine that are both practical and cost-effective. Currently most ketamine therapy is given intravenously in specialised clinics at considerable expense, but the author has successfully treated patients with low-dose sublingual ketamine and his patients have been able to safely take this at home.
Profits from the sales of this book will assist further research into the use of ketamine for the treatment of depression.
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Автор: Sanjay J. Mathew; Carlos A. Zarate, Jr. Название: Ketamine for Treatment-Resistant Depression ISBN: 3319826956 ISBN-13(EAN): 9783319826950 Издательство: Springer Рейтинг: Цена: 83850.00 T Наличие на складе: Невозможна поставка. Описание: This book brings together an international group of clinicians and researchers from a broad swath of inter-related disciplines to offer the most up-to-date information about clinical and preclinical research into ketamine and second-generation “ketamine-like” fast-acting antidepressants.Currently available antidepressant medications act through monoaminergic systems, are ineffective for many individuals suffering from depression, and are associated with a delayed onset of peak efficacy of several months. The unexpected emergence of ketamine, an anesthetic N-methyl-D-aspartate (NMDA) receptor antagonist, as a rapid-acting antidepressant has reinvigorated CNS drug discovery research and catalyzed investigation in patient populations historically ignored in antidepressant drug development programs, particularly treatment-resistant patients and those with suicidality. Recent industry and academic research efforts have coalesced to explore NMDA receptor and glutamatergic molecular targets that lack ketamine’s psychotomimetic side effects and abuse liability but retain its rapid onset of efficacy. However, many fundamental questions remain regarding the neurobiological mechanisms underlying ketamine’s rapid antidepressant effects and the puzzling persistence of benefits observed in some patients following a single dose. This book examines how insights from these studies are forging new conceptual models of the neurobiology of stress-related affective, anxiety, and addictive disorders and the nature of treatment resistance. It also discusses how ketamine’s rapid antidepressant effects provide a scientific platform to facilitate innovation in clinical trial designs pertaining to patient selection, choice of control group, outcome measures, and dose-optimization. This book brings together data and insights from this rapidly expanding and extraordinarily promising field of study. Readers will be able to extract integrated themes and useful insights from the material contained in these diverse chapters and appreciate the paradigm-shifting contributions of ketamine to modern psychiatry and clinical neuroscience research.
Автор: Francisco L?pez-Mu?oz; Venkataramanujam Srinivasan Название: Melatonin, Neuroprotective Agents and Antidepressant Therapy ISBN: 8132238427 ISBN-13(EAN): 9788132238423 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Невозможна поставка. Описание: This work is a guidebook for clinicians who are involved in treating depressive patients and also serves the research scientists who are working on the psychopharmacological mechanisms of antidepressant actions and psychopathological mechanisms underlying mood disorders.
Автор: Vazquez, Gustavo H. Название: Ketamine For Treatment-Resistant Depression ISBN: 0128210338 ISBN-13(EAN): 9780128210338 Издательство: Elsevier Science Рейтинг: Цена: 88690.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics.
Автор: Hyde Dr Stephen J. Название: Ketamine for Depression ISBN: 1503509540 ISBN-13(EAN): 9781503509542 Издательство: Неизвестно Рейтинг: Цена: 22250.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
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