The Search for Human Chromosomes: A History of Discovery, Wall Wilson John

Автор: Miller Orlando J., Therman Eeva
Название: Human Chromosomes
ISBN: 038795046X ISBN-13(EAN): 9780387950464
Издательство: Springer
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Цена: 83850.00 T
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Описание: The fourth edition of this well-known text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes. It covers both basic and up-to-date material on normal and defective chromosomes. This new edition is particularly strengthened by the complete revision of the material on the molecular genetics of chromosomes and chromosomal defects. The mapping and molecular analysis of chromosomes is one of the most exciting and active areas of modern biomedical research, and this book will be invaluable to scientists, students, technicians and physicians with an interest in the function and dysfunction of chromosomes. From the reviews of the third edition: "Each word "tells" in this concise gem of a human cytogenetics text...Superb organization makes this an excellent text...for any cytogenetics course." American Journal of Human Genetics"...the leading textbook in English on human cytogenetics." Cell

Автор: Kumaran Narayanan
Название: Bacterial Artificial Chromosomes
ISBN: 1493916513 ISBN-13(EAN): 9781493916511
Издательство: Springer
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Цена: 111790.00 T
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Описание: Bacterial Artificial Chromosomes, Second Edition expands upon the previous edition with current, detailed methods developed for working with BACs. Updated chapters included in this edition present fundamental techniques used for BAC construction and characterization, advanced procedures for introducing modifications, achieving gene expression from BAC vectors, applications of BACs in model organisms, and medical genetics and drug discovery. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step reproducible laboratory protocols, and tips to troubleshoot and avoid known pitfalls. Authoritative and cutting-edge, Bacterial Artificial Chromosomes, Second Edition seeks to aid scientists in advancing their research using these exciting BAC techniques and strategies.

Автор: Wall, Wilson John
Название: Search for human chromosomes
ISBN: 331926334X ISBN-13(EAN): 9783319263342
Издательство: Springer
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Цена: 79190.00 T
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Описание: This book is a broadly historical account of a remarkable and very exciting scientific story–the search for the number of human chromosomes. It covers the processes and people, culminating in the realization that discovering the number of human chromosomes brought as much benefit as unraveling the genetic code itself. With the exception of red blood cells, which have no nucleus and therefore no DNA, and sex cells, humans have 46 chromosomes in every single cell. Not only do chromosomes carry all of the genes that code our inheritance, they also carry them in a specific order. It is essential that the number and structure of chromosomes remains intact, in order to pass on the correct amount of DNA to succeeding generations and for the cells to survive. Knowing the number of human chromosomes has provided a vital diagnostic tool in the prenatal diagnosis of genetic disorders, and the search for this number and developing an understanding of what it means are the focus of this book.

Автор: Wolfgang Hennig
Название: Structure and Function of Eukaryotic Chromosomes
ISBN: 3662224380 ISBN-13(EAN): 9783662224380
Издательство: Springer
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Цена: 111790.00 T
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Описание: This book presents an overview of various aspects of chromosome research, written by leading experts of the respective fields, combining classic and recent molecular biological results. The variety and comprehensiveness make it a handbook of chromosome research for all scientists, teachers and graduate students interested in this field. Dieses Buch fa?t die unterschiedlichen Aspekte der Chromosomenforschung in Beitr?gen von f?hrenden Wissenschaftlern zusammen, wobei die klassischen Erkenntnisse mit neuesten Forschungsdaten zu einem umfassenden ?berblick ?ber das Gebiet kombiniert werden.

Автор: A.T. Sumner; A.C. Chandley
Название: Chromosomes Today
ISBN: 9401046603 ISBN-13(EAN): 9789401046602
Издательство: Springer
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Цена: 186330.00 T
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Описание: A few years ago it may have seemed to some that chromosome studies were being superseded by molecular biology, but the molecular biologists have now realized that they need to know about chromosomes, and indeed an important, if ill-defined discipline of `molecular cytogenetics` has grown up in recent years.

Автор: Kumaran Narayanan
Название: Bacterial Artificial Chromosomes
ISBN: 149395430X ISBN-13(EAN): 9781493954308
Издательство: Springer
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Цена: 102480.00 T
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Описание: Updated chapters included in this edition present fundamental techniques used for BAC construction and characterization, advanced procedures for introducing modifications, achieving gene expression from BAC vectors, applications of BACs in model organisms, and medical genetics and drug discovery.

Автор: Yuri B. Yurov; Svetlana G. Vorsanova; Ivan Y. Iour
Название: Human Interphase Chromosomes
ISBN: 1461465575 ISBN-13(EAN): 9781461465577
Издательство: Springer
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Цена: 156720.00 T
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Описание: This book explores the relationship of human interphase chromosomes to health and disease, presenting basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease.

Автор: Vittorio Sgaramella; Sandro Eridani
Название: Mammalian Artificial Chromosomes
ISBN: 1489939482 ISBN-13(EAN): 9781489939487
Издательство: Springer
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Цена: 93160.00 T
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Описание: We have strived to cover in Mammalian Artificial Chromosomes: Methods and Protocols all relevant areas of artificial chromosome research, from basic genetics to daring attempts to build new tools for genetic therapy.

Автор: Sumner
Название: Chromosomes.2002
ISBN: 0632054077 ISBN-13(EAN): 9780632054077
Издательство: Wiley
Цена: 31630.00 T
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Описание: Integrating classical knowledge of chromosome organisation with recent molecular and functional findings, this book presents an up-to-date view of chromosome organisation and function for advanced undergraduate students studying genetics. The organisation and behaviour of chromosomes is central to genetics and the equal segregation of genes and chromosomes into daughter cells at cell division is vital. This text aims to provide a clear and straightforward explanation of these complex processes.Following a brief historical introduction, the text covers the topics of cell cycle dynamics and DNA replication; mitosis and

Автор: C. Nicolini
Название: Genome Structure and Function
ISBN: 9401063389 ISBN-13(EAN): 9789401063388
Издательство: Springer
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Цена: 186330.00 T
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Описание: Proceedings of the NATO Advanced Study Institute on Genome Structure and Function, held in Marciana Marina, Elba, Italy, 13-23 June 1996

Автор: N. Henriquez-Gil; J.S. Parker; M. Puertas
Название: Chromosomes Today
ISBN: 9401071861 ISBN-13(EAN): 9789401071864
Издательство: Springer
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Цена: 139750.00 T
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Описание: Chromosomes Today Volume 12 records the plenary proceedings of the 12th triennial International Chromosone Conference, presenting an overview of the current concerns in the developing studies of animal, plant and human cytogenetics.

Автор: Iourov Ivan, Vorsanova Svetlana, Yurov Yuri
Название: Human Interphase Chromosomes: Biomedical Aspects
ISBN: 3030625346 ISBN-13(EAN): 9783030625344
Издательство: Springer
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Цена: 93160.00 T
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Описание: This second edition focuses on the study of human interphase chromosomes and its relation to health and disease. Orchestrated organization and behavior of the human genome in interphase nuclei at chromosomal level has been repeatedly shown to play a significant role in almost all basic biological processes involved in the processing and inheritance of genetic information within and between species. Accordingly, post-genomic bioscience appeals to basic and applied studies of interphase nuclei genetics and genomics with special attention to interphase chromosome behavior in health and disease. Additionally, elucidating the role of interphase chromosome behavior during development, chromosome/DNA replication, DNA reparation opens new horizons for basic and applied bioscience Studies of interphase nuclei have an appreciable impact on different areas of biomedical sciences such as cell biology, neurobiology, cancer research, developmental biology, epigenetics, cytogenetics, and medical genetics, as a whole. Moreover, development of innovative and emergent technologies to analyze interphase nuclei are closely associated with application of these techniques in diagnostic and research practices to solve reproductive problems (including infertility and spontaneous abortions), to investigate congenital malformations (including those produced by aneuploidy and other chromosome abnormalities); genetic diseases (including cardiac, immune, neurological and psychiatric diseases), and cancer. This second edition serves as a source of updated valuable information and promising ideas for a wide audience of professionals in biomedicine including researchers, scientists, and healthcare professionals in human genetics, cytogenetics, and developmental biology.