Tumor Angiogenesis Assays: Methods and Protocols, Ribatti Domenico

Автор: Figg
Название: Angiogenesis
ISBN: 0387715177 ISBN-13(EAN): 9780387715179
Издательство: Springer
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Цена: 222850.00 T
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Описание: Dr Judah Folkman (1933-2008) was considered the `father of angiogenesis`. Because of Folkman`s discovery and research, the possibilities of angiogenic therapy have broadened beyond cancer to many noncancerous diseases. This book presents a summary of tumor angiogenesis.

Автор: Ribatti
Название: Tumor Angiogenesis Assays
ISBN: 1493939971 ISBN-13(EAN): 9781493939978
Издательство: Springer
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Цена: 130430.00 T
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Описание: This volume aims to provide a range of methods and protocols for studying tumor angiogenesis in vitro and in vivo to reflect advances in the field. The chapters in this book cover topics such as: morphological aspects of tumor angiogenesis, aortic ring assay and its use for the study of tumor angiogenesis, ex vivo tissue culture model for anti-angiogenic drug testing, transgenic zebrafish, orthotopic models of ovarian cancer, and uncovering metabolic effects of anti-angiogenic therapy in tumors by induced metabolic bioluminescence imaging. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.Cutting edge and thorough, Tumor Angiogenesis Assays: Methods and Protocols is a valuable resource for anyone interested in tumor angiogenesis assay research.

Автор: Enrique Zudaire; Frank Cuttitta
Название: The Textbook of Angiogenesis and Lymphangiogenesis: Methods and Applications
ISBN: 9400797834 ISBN-13(EAN): 9789400797833
Издательство: Springer
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Цена: 69650.00 T
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Описание: Their active roles in many diseases make angio- and lymphangiogenesis high-profile targets of medical research. This richly illustrated text updates readers on a fast-moving field through readily reproducible protocols for many of the latest techniques.

Автор: Domenico Ribatti
Название: The Role of Microenvironment in the Control of Tumor Angiogenesis
ISBN: 3319278185 ISBN-13(EAN): 9783319278186
Издательство: Springer
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Цена: 121890.00 T
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Описание:

Prelims

1. Tumor microenvironment

1.1. Metastatic cascade

1.2. Epithelial-mesenchymal transition

1.3. The extracellular matrix

2. Tumor blood vessels and tumor endothelial cells

2.1. Tumor basement membrane

Автор: Dieter Marm?; Norbert Fusenig
Название: Tumor Angiogenesis
ISBN: 3662517981 ISBN-13(EAN): 9783662517987
Издательство: Springer
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Цена: 334480.00 T
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Описание: With contributions by numerous experts

Автор: Dieter Marm?
Название: Tumor Angiogenesis
ISBN: 3319336711 ISBN-13(EAN): 9783319336718
Издательство: Springer
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Цена: 512430.00 T
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Описание: This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.

Автор: Ribatti Domenico
Название: The Role of Microenvironment in the Control of Tumor Angiogenesis
ISBN: 3319802224 ISBN-13(EAN): 9783319802220
Издательство: Springer
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Цена: 93160.00 T
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Описание: This work describes the importance of tumor microenvironment in favouring tumor progression and angiogenesis. Under physiological conditions, angiogenesis is dependent on the balance of positive and negative angiogenic modulators within the vascular microenvironment and requires the functional activities of a number of molecules, including angiogenic factors, extracellular matrix proteins, adhesion molecules and proteolytic enzymes. In normal tissues, vascular quiescence is maintained by the dominant influence of endogenous angiogenesis inhibitors over angiogenic stimuli. Tumor angiogenesis is linked to a switch in the balance between positive and negative regulators, and mainly depends on the release by inflammatory or neoplastic cells of specific growth factors for endothelial cells, that stimulate the growth of the blood vessels of the host or the down-regulation of natural angiogenesis inhibitors. In particular, the inflammatory infiltrate may contribute to tumor angiogenesis, and there are many reports of associations between tumor inflammatory infiltrate, vascularity and prognosis. New therapeutic approaches have been developed with the aim to control tumor angiogenesis through targeting of different components of tumor microenvironment.

Автор: Dieter Marm?
Название: Tumor Angiogenesis
ISBN: 3319336738 ISBN-13(EAN): 9783319336732
Издательство: Springer
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Цена: 372670.00 T
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Описание: This exhaustive work shows that new therapies using anti-angiogenic drugs are of particular importance because they can be used against many different types of cancer, as tumor angiogenesis seems to be involved in most if not all solid metastasizing malignancies. The first part of this book summarizes the knowledge acquired on the molecular entities that play a role in tumor angiogenesis and their mechanisms of action. Furthermore, the identification of molecular markers and their validation as predictive and/or prognostic tools is reviewed. In the second and most important part, the clinical applications of anti-angiogenic treatments are documented for a wide variety of tumors. In particular, the modes of combination with other targeted and/or cytotoxic cancer therapies are presented.?

Автор: O`Riely Vince
Название: Tumor Angiogenesis
ISBN: 1632413760 ISBN-13(EAN): 9781632413765
Издательство: Неизвестно
Цена: 178950.00 T
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Описание: Extensive information regarding the topic of tumor angiogenesis has been compiled in this advanced book. Tumor angiogenesis is the procedure primarily responsible for the generation of new blood vessels that boost tumor development and metastasis. The pro

Название: Tumor Angiogenesis Regulators
ISBN: 1466580976 ISBN-13(EAN): 9781466580978
Издательство: Taylor&Francis
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Цена: 56130.00 T
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Описание: The emphasis of this book is on mechanisms and pathways regulating the expression and actions of classical and novel tumor angiogenesis regulators. The contributors discuss their underlying biology as well as anti-angiogenic drugs currently in use to fight different cancers. The book provides an insight on how factors such as obesity, diabetes, and

Автор: O`Riely Vince
Название: Global Researches in Tumor Angiogenesis
ISBN: 1632412330 ISBN-13(EAN): 9781632412331
Издательство: Неизвестно
Цена: 134050.00 T
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Описание: This book discusses the global researches in the field of tumor angiogenesis. Angiogenesis is an extension process of the cardiovascular system within human body. It is mostly instigated by the need for oxygen and nutrients by the fast growing tissue and

Автор: Ribatti
Название: History of Research on Tumor Angiogenesis
ISBN: 9048181569 ISBN-13(EAN): 9789048181568
Издательство: Springer
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Цена: 121890.00 T
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Описание: In 1971, J. Folkman hypothesized that tumor growth is angiogenesis-dependent. In 2004, the FDA approved the first angiogenesis inhibitor. This book compiles the relevant literature of that history and emphasizes the antiangiogenic approach to treat tumors.