The Pangenome 9781013277061

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Автор: Tettelin Hervй, Medini Duccio
Название: The Pangenome
ISBN: 9781013277061
Издательство: Saint Philip Street Press
Классификация:

Медицинская генетика

Прикладная математика

Эволюция

Генетика (немедицинская)

Микробиология (немедицинская)

ISBN-10: 1013277066
Обложка/Формат: Paperback
Страницы: 310
Вес: 0.72 кг.
Дата издания: 09.10.2020
Язык: English
Размер: 27.99 x 21.59 x 1.65 cm
Читательская аудитория: General (us: trade)
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Поставляется из: США
Описание: This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The books respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.

This work was published by Saint Philip Street Press pursuant to a Creative Commons license permitting commercial use. All rights not granted by the works license are retained by the author or authors.

The Pangenome, Tettelin Hervй, Medini Duccio