Genetics And Genomics Of Eye Disease, Gao, Xiaoyi Raymond
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 64300.00 T Наличие на складе: Нет в наличии. Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
Автор: Wakeley John Название: Coalescent Theory ISBN: 0974707759 ISBN-13(EAN): 9780974707754 Издательство: Macmillan Learning Рейтинг: Цена: 59390.00 T Наличие на складе: Невозможна поставка. Описание: Coalescent theory provides the foundation for molecular population genetics and genomics. It is the conceptual framework for studies of DNA sequence variation within species, and is the source of essential tools for making inferences about mutation, recombination, population structure and natural selection from DNA sequence data.
Автор: Wilkins Ralph G. Название: Animal Genetics for Chemists ISBN: 178262760X ISBN-13(EAN): 9781782627609 Издательство: Royal Society of Chemistry Рейтинг: Цена: 49270.00 T Наличие на складе: Поставка под заказ. Описание: Setting out to cover the fundamentals of the subject, this book features humans, other mammals and occasionally other animals to illustrate principles.
Автор: Michael Hehenberger, Zhi Xia Название: Our Animal Connection: What Sapiens Can Learn From Other Species ISBN: 9814800481 ISBN-13(EAN): 9789814800488 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The book covers the many ways humans benefit from interactions with other living species. By studying animals of all kinds and sizes, from microbial organisms to elephants and whales, we can learn about their adaptations to extreme conditions on planet Earth, about the evolutionary development of specialized capabilities, and about their ways to defend themselves against predators and diseases. We discuss the strengths and weaknesses of Homo Sapiens, and how the study of animals can make us stronger and healthier. To increase our knowledge of genetics, molecular and cell biology, physiology and medicine, we need to study model organisms. To cure human disease, we can learn from animals how they have evolved ways to protect themselves. To improve our human performance, we can study the animal kingdom’s top performers and possibly learn from their successes. Finally, we review genetic engineering techniques that can translate our existing and future animal connections into benefits for human health and performance.
Автор: Natasa Przulj Название: Analyzing Network Data in Biology and Medicine: An Interdisciplinary Textbook for Biological, Medical and Computational Scientists ISBN: 1108432239 ISBN-13(EAN): 9781108432238 Издательство: Cambridge Academ Рейтинг: Цена: 51750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Bringing together leading experts in the field of network data analysis, this text introduces biological concepts and biotechnologies producing the data, graph and network theory, cluster analysis and machine learning. Using real-world biological and medical examples, applications of these theories are discussed and creative thinking is encouraged in the analysis of such complex network data sets.
Автор: Redei Название: Encyclopedia of Genetics, Genomics, Proteomics, and Informatics. 2008 ISBN: 1402067534 ISBN-13(EAN): 9781402067532 Издательство: Springer Рейтинг: Цена: 870740.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An encyclopedia that covers the basics and the developments in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents.
Автор: Michael Dean Название: From Gene to Therapy: Understanding Human Disease through Genetics ISBN: 1615047522 ISBN-13(EAN): 9781615047529 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 33400.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases are provided, drawing on the author`s research.
Автор: Michael Dean Название: From Gene to Therapy: Understanding Human Disease through Genetics ISBN: 1615047719 ISBN-13(EAN): 9781615047710 Издательство: Mare Nostrum (Eurospan) Цена: 50120.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Lecture provides an overview of the progress made in molecular medicine applying genetics and genomics to the understanding, diagnosis, and treatment of human diseases. Specifically, the methods for identifying genes involved in human diseases are described. Examples from 10 genes and diseases will be provided, drawing on the author's research. Topics include examples from simple Mendelian diseases, such as cystic fibrosis, inherited cancers, oncogenes activated by chromosomal translocations, host genes involved in infectious disease, genes identified via genomewide association studies, pathogens causing cancer, and gene families contributing to multiple diseases. For each example, historical details will be provided as background for readers to understand the context and process of the discoveries, technologies explained, and current understanding and treatment implications detailed.
This title includes a number of Open Access chapters.
This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:
host-pathogen interactions
causal relationships between genes and the environment
the effects of environmental chemicals on gene expression
DNA methylation
The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.
This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.
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