This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Brunton, Laurence; Knollmann, Bjorn; Hilal-Dandan, Randa Название: Goodman and Gilman`s The Pharmacological Basis of Therapeutics, 13th Edition ISBN: 1259584739 ISBN-13(EAN): 9781259584732 Издательство: McGraw-Hill Рейтинг: Цена: 0.00 T Наличие на складе: Невозможна поставка. Описание: The gold-standard of pharmacology texts - updated to reflect the latest developments and breakthroughs
Автор: Thangaraj Parimelazhagan Название: Pharmacological Assays of Plant-Based Natural Products ISBN: 3319268104 ISBN-13(EAN): 9783319268101 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: After a detailed in vitro investigation including nutritional and anti-nutritional analyses, medicinal properties were tested with various in vivo models for anti-inflammatory, analgesic, anti-pyretic, anticancer and anti-diabetic properties, as well as wound healing, neurodegenerative diseases, etc.
Автор: Jiaju Zhou; Guirong Xie; Xinjian Yan Название: Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications ISBN: 3642440703 ISBN-13(EAN): 9783642440700 Издательство: Springer Рейтинг: Цена: 304750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This set of six volumes provides a systematic and standardized description for 23,033 chemical components isolated from 6,734 medicinal plants. It provides a chemical structure with stereo-chemistry bonds for each chemical component.
Автор: Jiaju Zhou; Guirong Xie; Xinjian Yan Название: Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications ISBN: 3642445454 ISBN-13(EAN): 9783642445453 Издательство: Springer Рейтинг: Цена: 304750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This set of six volumes provides a systematic and standardized description for 23,033 chemical components isolated from 6,734 medicinal plants. It provides a chemical structure with stereo-chemistry bonds for each chemical component.
Автор: Jiaju Zhou; Guirong Xie; Xinjian Yan Название: Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications ISBN: 3642434843 ISBN-13(EAN): 9783642434846 Издательство: Springer Рейтинг: Цена: 304750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This 6 volume set offers a systematic, standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books and articles published in Chinese and international journals, organized for easy retrieval and use.
Автор: Jiaju Zhou; Guirong Xie; Xinjian Yan Название: Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications ISBN: 3642434924 ISBN-13(EAN): 9783642434921 Издательство: Springer Рейтинг: Цена: 269260.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This set of six volumes provides a systematic and standardized description of 23,033 chemical components isolated from 6,926 medicinal plants, collected from 5,535 books/articles published in Chinese and international journals. A chemical structure with stereo-chemistry bonds is provided for each chemical component, in addition to conventional information, such as Chinese and English names, physical and chemical properties. It includes a name list of medicinal plants from which the chemical component was isolated. Furthermore, abundant pharmacological data for nearly 8,000 chemical components are presented, including experimental method, experimental animal, cell type, quantitative data, as well as control compound data. The seven indexes allow for complete cross-indexing. Regardless whether one searches for the molecular formula of a compound, the pharmacological activity of a compound, or the English name of a plant, the information in the book can be retrieved in multiple ways.
Автор: Jiaju Zhou; Guirong Xie; Xinjian Yan Название: Encyclopedia of Traditional Chinese Medicines - Molecular Structures, Pharmacological Activities, Natural Sources and Applications ISBN: 3642438628 ISBN-13(EAN): 9783642438622 Издательство: Springer Рейтинг: Цена: 304750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This set of six volumes provides a systematic and standardized description for 23,033 chemical components isolated from 6,734 medicinal plants. It provides a chemical structure with stereo-chemistry bonds for each chemical component.
Автор: Ajeet Singh, Padam Singh, Navneet Bithel Название: Handbook of Research on Pharmacological Uses of Medicinal Plants and Natural Products ISBN: 1799820947 ISBN-13(EAN): 9781799820949 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 684330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A vast majority of the world's population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services.
Handbook of Research on Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.
