Prions and Neurodegenerative Diseases (Volume 175) (Progress in Molecular Biology and Translational Science, Volume 175), Legname, Giuseppe
Автор: Kovacs Название: Neuropathology of Neurodegenerative Diseases Book and Online ISBN: 1107442427 ISBN-13(EAN): 9781107442429 Издательство: Cambridge Academ Рейтинг: Цена: 93990.00 T Наличие на складе: Поставка под заказ. Описание: This practical guide to the diagnosis of neurodegenerative diseases discusses modern molecular techniques, morphological classification, fundamentals of clinical symptomology, diagnostic pitfalls and immunostaining protocols. It is based on the proteinopathy concept of neurodegenerative disease, which has influenced classification and provides new strategies for therapy. Numerous high-quality images, including histopathology photomicrographs and neuroradiology scans, accompany the description of morphologic alterations and interpretation of immunoreactivities. Diagnostic methods and criteria are placed within recent developments in neuropathology, including the now widespread application of immunohistochemistry. To aid daily practice, the guide includes diagnostic algorithms and offers personal insights from experienced experts in the field. Special focus is given to the way brain tissue should be handled during diagnosis. This is a must-have reference for medical specialists and specialist medical trainees in the fields of pathology, neuropathology and neurology working with neuropathologic features of neurodegenerative diseases. The book is packaged with a password, giving the user online access to all the text and images.
Автор: Weissbrod Название: Neurologic and Neurodegenerative Diseases of the Larynx ISBN: 303028851X ISBN-13(EAN): 9783030288518 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Название: Protein Misfolding in Neurodegenerative Diseases ISBN: 036738812X ISBN-13(EAN): 9780367388126 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Research focused on protein folding, misfolding, and aggregation is leading to major advances across biochemistry and medicine. The elucidation of a folding code is proving to be of extreme importance in the postgenomic era, where a number of orphan genes have been identified for which no clear function has yet been established. This research is starting to shed light on the molecular and biochemical basis of a number of neurodegenerative diseases of dramatic impact.
Protein Misfolding inNeurodegenerative Diseases: Mechanisms and Therapeutic Strategies addresses key issues concerning protein misfolding and aggregation in neurodegenerative diseases. Building on recent developments, including the recognition of protein misfolding as both a marker and a causal agent, the text presents the work of those who are actively pursuing more effective treatments, as well as preventative measures, and a possible cure. These include the use of molecular chaperones to control misfolding and novel pharmaceuticals, as well as the potential role of various inhibitors and NSAIDS.
A Comprehensive Multifaceted Examination of the Complex Causal Agents Implicated in Protein Misfolding
Divided into five sections, this groundbreaking text provides up-to-date accounts for Alzheimer's, Parkinson's, Huntington's, Amyotrophic Lateral Sclerosis and Transmissible Spongiform Encephalitis. It also explores the highly likelihood that multiple factors, including oxidative stress, play a role in these complex diseases.
Автор: Judit Ov?di; Ferenc Orosz Название: Protein folding and misfolding: neurodegenerative diseases ISBN: 9048181275 ISBN-13(EAN): 9789048181278 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Offering all the latest in the study of neurodegenerative diseases, this book reviews the molecular events initiated by unfolded or misfolded proteins leading to conformational human diseases, especially those found in Parkinson`s and Alzheimer`s diseases.
Автор: Theresa Natalie Название: Encyclopedia of Neurodegenerative Diseases: Volume III (Integrated Processes) ISBN: 1632411784 ISBN-13(EAN): 9781632411785 Издательство: Неизвестно Цена: 178950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Integrated processes of neurodegenerative diseases have been provided in this all-inclusive book. It concentrates on biological mechanisms and neuoprotection of disease growth. It lays stress on the fundamental biological processes of neurodegeneration in
Автор: Theresa Natalie Название: Encyclopedia of Neurodegenerative Diseases: Volume II (Therapeutic Intervention and Mechanisms) ISBN: 1632411776 ISBN-13(EAN): 9781632411778 Издательство: Неизвестно Цена: 156590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines generic mechanisms in neurodegenerative diseases. It throws light on the pathophysiological complexities of the mechanisms and factors that are most probably involved in a number of neurodegenerative and neuroinflammatory diseases inclu
Автор: Theresa Natalie Название: Encyclopedia of Neurodegenerative Diseases: Volume V (Advanced Topics) ISBN: 1632411806 ISBN-13(EAN): 9781632411808 Издательство: Неизвестно Цена: 134050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book targets various diseases, such as Alzheimer's disease, frontotemporal dementia and various tauopathies. It also provides a profound explanation of various neurodegenerative diseases with novel theories of understanding the etiology, pathological
Автор: Aschner, Michael Название: Environmental Factors in Neurodegenerative Diseases ISBN: 0128127643 ISBN-13(EAN): 9780128127643 Издательство: Elsevier Science Рейтинг: Цена: 168430.00 T Наличие на складе: Поставка под заказ. Описание:
Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Edited by leading subject experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. As a result, this serial is an essential and unique resource for researchers and graduate students alike.
Includes, in one single publication, a selection of comprehensive reviews devoted to neurotoxicology
Edited by high-profile, leading academics in the field, ensuring a quality publication for subscribers
Aims to widen the scope for participation by international contributors, researchers and editorial board members outside North America
Serves a broad audience of university faculty, researchers and students, as well as the industry, drug development companies and the government
Автор: White, Anthony R. Название: Biometals in Neurodegenerative Diseases ISBN: 0128045620 ISBN-13(EAN): 9780128045626 Издательство: Elsevier Science Рейтинг: Цена: 132500.00 T Наличие на складе: Поставка под заказ. Описание:
Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer's Disease, Parkinson's Disease, Motor Neuron Disease, Autism and lysosomal storage disorders.
This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases.
Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.
Authoritative and timely resource bringing together the major findings in the field for those with an interest in metals and their role in the brain function, disease, and as therapeutic targets
Written for academic researchers, clinicians, and advanced graduate students studying, or treating, patients in neurodegeneration, neurochemistry, neurology and neurotoxicology
Edited by international leaders in the field who have contributed greatly to the study of metals in neurodegenerative diseases
Автор: Theresa Natalie Название: Encyclopedia of Neurodegenerative Diseases: Volume I (Disease Mechanisms) ISBN: 1632411768 ISBN-13(EAN): 9781632411761 Издательство: Неизвестно Цена: 156590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The mechanisms of neurodegenerative diseases are elucidated in this book. It throws light on the pathophysiological complexities of the mechanisms and factors that are most probably involved in a number of neurodegenerative and neuroinflammatory diseases
Автор: Abel Lajtha; Naren L. Banik Название: Role of Proteases in the Pathophysiology of Neurodegenerative Diseases ISBN: 1441933603 ISBN-13(EAN): 9781441933607 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Researchers seeking problems that offer more hope of success often avoid subjects that seem to be difficult to approach experimentally, or subjects for which experimental results are difficult to interpret.
Автор: Giuseppe Legname, Gabriele Giachin Название: Prion Phenomena in Neurodegenerative Diseases: New Frontiers in Neuroscience ISBN: 1634833996 ISBN-13(EAN): 9781634833998 Издательство: Nova Science Цена: 211200.00 T Наличие на складе: Невозможна поставка. Описание: The most fascinating and unique feature of prion diseases is that they are caused almost exclusively by a proteinaceous and infectious particle termed prions by the Nobel Prize laureate S B Prusiner, who discovered this class of pathogens. In the latter part of the 1990s, mad-cow disease, a disease caused by prions acquired through foodborne transmission, raised unprecedented public concern due to the concrete possibility that prions in animals could be transmitted to humans through the food chain. For roughly two decades, prions were under intense scrutiny and many studies were undertaken worldwide. These investigations have led our community to a better risk assessment and management of prion diseases in humans and in animals, substantially limiting the possibility of new prion epidemics. Nowadays, prions have been brought once again to the foreground after the discovery that a variety of neurodegenerative diseases, in particular Alzheimers disease, Parkinsons disease and amyotrophic lateral sclerosis, share fundamental features with prions, including protein misfolding and aggregation in the brain, cell-to-cell transmission and in vivo infectivity. Therefore, studying prions might help to understand the pathological mechanism of these disorders. The Prion Phenomena In Neurodegenerative Diseases: New Frontiers in Neuroscience is a book that benefits from the contribution of leading scientists in different fields of neuroscience, including Gianluigi Zanusso, Holger Wille, Fabrizio Tagliavini, Andrew F Hill, Jerson L Silva, Vladimir N Uversky, Henrike Heise, David W Colby, Neil R Cashman and the Nobel Prize laureate Eric R Kandel. This chapter collection discusses the development of prions and their various diseases, and provides a detailed overview about the state of the art of the novel prion phenomena observed in other fatally damaging protein misfolding disorders. This book represents an up-to-date review of different protein-misfolding diseases, serving as an invaluable tool for both specialized researchers working in the field of neurodegeneration and for a broad spectrum of academic readers that wish to learn more about the prion phenomena.
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