Current Topics in Nonclinical Drug Development, 

Автор: Joerg Bluemel
Название: The Nonhuman Primate in Nonclinical Drug Development and Safety A
ISBN: 0124171443 ISBN-13(EAN): 9780124171442
Издательство: Elsevier Science
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Цена: 140360.00 T
Наличие на складе: Невозможна поставка.
Описание: The Nonhuman Primate in Drug Development and Safety Assessment is a valuable reference dedicated to compiling the latest research on nonhuman primate models in nonclinical safety assessment, regulatory toxicity testing and translational science. By covering important topics such as study planning and conduct, inter-species genetic drift, pathophysiology, animal welfare legislation, safety assessment of biologics and small molecules, immunotoxicology and much more, this book provides scientific and technical insights to help you safely and successfully use nonhuman primates in pharmaceutical toxicity testing. A comprehensive yet practical guide, this book is intended for new researchers or practicing toxicologists, toxicologic pathologists and pharmaceutical scientists working with nonhuman primates, as well as graduate students preparing for careers in this area.

Автор: Carrie Markgraf
Название: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals
ISBN: 0124201725 ISBN-13(EAN): 9780124201729
Издательство: Elsevier Science
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Цена: 116780.00 T
Наличие на складе: Невозможна поставка.
Описание: Nonclinical Assessment of Abuse Potential for New Pharmaceuticals offers a complete reference on the current international regulatory guidelines and details best practice methodology for the three standard animal models used to evaluate abuse potential: physical dependence, self-administration and drug discrimination. This book also includes chapters on alternative models and examples of when you should use these alternatives. Case histories are provided at the end of the book to show how the data generated from the animal models play a pivitol role in the submission package for a new drug. By incorporating all of this information into one book, Nonclinical Assessment of Abuse Potential for New Pharmaceuticals is your single resource for everything you need to know to understand and implement the assessment of abuse liability.