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Animal Models of Diabetes, 


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Название:  Animal Models of Diabetes
ISBN: 9780367389253
Издательство: Taylor&Francis
Классификация:


ISBN-10: 0367389258
Обложка/Формат: Paperback
Страницы: 384
Вес: 0.71 кг.
Дата издания: 20.12.2019
Язык: English
Издание: 2 ed
Размер: 226 x 152 x 18
Читательская аудитория: Tertiary education (us: college)
Основная тема: Diabetes
Подзаголовок: Frontiers in Research
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

As the incidence of diabetes increases worldwide, the need for recommendations on how to prevent and treat the condition grows exponentially, and so does the need for an authoritative source for information on the appropriate models to study the condition. The new edition of Animal Models of Diabetes is that source. The book presents updated and expanded information regarding the use of models in experiments with both Type 1 and Type 2 diabetes.

The new edition compiles relevant time-saving information on well-recognized models, including various mice, rats, minipigs, and Rhesus monkeys, and provides extensive references for more in-depth study. It contains new and updated referenced reviews on animals with induced obesity as well as observations on retinopathy in spontaneous diabetes resembling human lesions. The book discusses nutritionally diabetes-prone animals and considerations of insulin resistance and obesity. The contributors also address the importance of recent findings on the pathogenesis of diabetes and its complications in relation to human disease.

Including contributions from prominent experts in the field, the book brings together scattered data and lucidly presents it. This promotes the understanding of the etiopathology of diabetes and offers a new grasp of the insulin action, its negative feedback leading to insulin resistance, and its detrimental outcomes. The book also includes new knowledge on specific complications of diabetes, offering an incentive to test advanced modalities to prevent and inhibit their occurrence.



Animal Models in Diabetes Research

Автор: Hans-Georg Joost; Hadi Al-Hasani; Annette Sch?rman
Название: Animal Models in Diabetes Research
ISBN: 1493962566 ISBN-13(EAN): 9781493962563
Издательство: Springer
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Цена: 135090.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Detailing the latest protocols for researching animal models of diabetes, especially resistant groups of rodents such as the NOD mouse, and including expert advice on implementation, this is a valuable new volume in the Methods in Molecular Biology series.

Lessons from Animal Diabetes VI

Автор: Eleazar Shafrir
Название: Lessons from Animal Diabetes VI
ISBN: 1461286581 ISBN-13(EAN): 9781461286585
Издательство: Springer
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Цена: 213360.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Best of Five MCQS for the Endocrinology and Diabetes SCE

Название: Best of Five MCQS for the Endocrinology and Diabetes SCE
ISBN: 0198729332 ISBN-13(EAN): 9780198729334
Издательство: Oxford Academ
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Цена: 51730.00 T
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Описание: Best of Five MCQs for the Endocrinology and Diabetes SCE is designed specifically for this new high-stakes exam. It contains over 300 best of five questions with explanatory answers, each accurately reflecting the layout of questions in the exam.

Animal Models in Cardiovascular Research

Автор: David R. Gross
Название: Animal Models in Cardiovascular Research
ISBN: 0387959610 ISBN-13(EAN): 9780387959610
Издательство: Springer
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Цена: 177010.00 T
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Описание: Describes advances in our understanding of the cardiovascular system from studies conducted in a variety of animal models. This book covers preoperative care, pre-anesthesia, chemical restraint, and includes a section on pain recognition and analgesia particularly in rodents.

Animal models for retinal diseases series: neuromethods, vol. 46

Автор: Pang, Iok-Hou; Clark, Abbot F. (Eds.) Pang, Iok-H
Название: Animal models for retinal diseases series: neuromethods, vol. 46
ISBN: 1607615401 ISBN-13(EAN): 9781607615408
Издательство: Springer
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Цена: 149060.00 T
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Описание: Retinal diseases are among the leading causes of irreversible visual impairment and blindness. This vital book provides an easily accessible and authoritative reference for animal models of the most common and important retinal diseases.

Animal Models in Cardiovascular Research

Автор: Gross
Название: Animal Models in Cardiovascular Research
ISBN: 1441930701 ISBN-13(EAN): 9781441930705
Издательство: Springer
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Цена: 177010.00 T
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Описание: This fully revised and updated third edition reflects intensified interest in the field and provides information essential to researchers interested in using animal models for cardiovascular research, or any research requiring normal cardiovascular function.

Animal Models of Neurological Disease, I

Автор: Alan A. Boulton; Glen B. Baker; Roger F. Butterwor
Название: Animal Models of Neurological Disease, I
ISBN: 0896032086 ISBN-13(EAN): 9780896032088
Издательство: Springer
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Цена: 172350.00 T
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Описание: The use of animal models continues to be the most reliable way of studying pathophysiologic mechanisms as well as treatments for neurological disorders. These two companion volumes highlight new information and techniques available in this rapidly growing area.

Animal Models for Medications Screening to Treat Addiction,126

Автор: Richard L Bell
Название: Animal Models for Medications Screening to Treat Addiction,126
ISBN: 0128040130 ISBN-13(EAN): 9780128040133
Издательство: Elsevier Science
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Цена: 162820.00 T
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Описание:

"Animal Models for Medications Screening to Treat Addiction," the latest volume in the "International Review of Neurobiology" series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field.
Brings together information on the current state of medication development for drug addiction using animal modelsContains comprehensive descriptions of various models associated with many forms of drug addictionAdds new information for translational research in the field of drug addiction

Animal Models of T Cell-Mediated Skin Diseases

Автор: T. Zollner; Harald Renz; Khusru Asadullah
Название: Animal Models of T Cell-Mediated Skin Diseases
ISBN: 3642422055 ISBN-13(EAN): 9783642422058
Издательство: Springer
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Цена: 148010.00 T
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Описание: Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character.

Animal Models in Cancer Drug Discovery

Автор: Azmi, Asfar
Название: Animal Models in Cancer Drug Discovery
ISBN: 0128147040 ISBN-13(EAN): 9780128147047
Издательство: Elsevier Science
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Цена: 153830.00 T
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Описание:

Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read.

Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.

  • Encompasses discussions on innovative animal models, xenograft, genetic models, primary models, organoid systems, humanized and other models in modern biology paradigms that are enhancing research in the field of drug discover
  • Covers the use of these models in personalized medicine, immunotherapy, toxicology, pre-IND assessments and related drug development arenas
  • Presents protocols, procedures, and a comprehensive glossary to help new readers understand technical terms and specialized nomenclature


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