This unique advanced textbook provides a clear and comprehensive overview of gene delivery, gene therapy and genetic pharmacology, with descriptions of the main gene transfer vectors and a set of selected therapeutic applications, along with safety considerations. The second edition features new groundbreaking material on genome editing using the recently discovered CRISPR/Cas9 system and on cancer immunotherapy by CAR-T cells. It also presents the historical milestone of gene therapy application in the field of severe combined immunodeficiency, and other fields of gene therapy and molecular medicine.
The use of gene transfer is exponentially growing in the scientific and medical communities for day-to-day cell biology experiments and swift development of gene therapy, which is already revolutionizing medicine. In this advanced textbook, more than 30 leading scientists come together to explore these topics.
This educational introduction provides the background material needed to further explore the subject as well as relevant research literature. It is an invaluable resource to Master, PhD or MD students, post-doctoral scientists or medical doctors, as well as any scientist wishing to deliver a gene or synthetic nucleotide or develop a gene therapy strategy. The second edition's simple and synthetic content will be of value to any reader interested in the biological and medical revolution derived from the elucidation of the human genome.
Автор: Jack A. Roth Название: Gene-Based Therapies for Cancer ISBN: 1461426340 ISBN-13(EAN): 9781461426349 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume on developing gene therapies for many cancers emphasizes translational gene therapy approaches. Chapters include specific gene delivery technologies and their application to various cancers with extensive discussions of ongoing clinical trials.
Автор: Los Название: Apoptotic Pathways as Target for Novel Therapies in Cancer & Other Diseases ISBN: 0387233849 ISBN-13(EAN): 9780387233840 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Поставка под заказ. Описание: As our understanding of apoptotic pathway expands, we are coming to realize the great potential of utilizing this pathway to treat diseases such as cancer. The book attempts to review, summarize, and speculate on the apoptotic pathways, how are they regulated and how targeted therapies are being used to treat a wide variety of diseases. Special emphasis is placed on cancer since new treatments either being developed or currently in the clinical setting are showing great promise to increase survival rates for cancer patients. Chapters will address the biology behind regulating the apoptotic pathways and what goes wrong in disease states whereas other chapters will concentrate on new therapies targeting apoptotic pathways. The reader by the end of the book should have greater insight into the understanding and utilization of apoptotic pathways to fight diseases such as cancer.
Автор: E. Garaci; Allan L. Goldstein Название: Combination Therapies ISBN: 1461364728 ISBN-13(EAN): 9781461364726 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: These molecules, termed biological response modifiers (BRMs) , have been sequenced, synthesized and produced in large enough quantities to test in animals and humans resulting in the development of new approaches to the treatment of human disease, in particular, cancers and infectious diseases.
Автор: Joseph P. Hou Название: The Healing Power of Ginseng ISBN: 0367211459 ISBN-13(EAN): 9780367211455 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book covers the properties and uses of four varieties of ginseng in the world with focus on American and Asian types of ginseng. It discusses healing properties of ginseng, growing ginseng plants, chemical, nutritional, medical and pharmacological properties, detoxification, longevity and proper usage of the root.
Автор: Hoffman Janet Название: Steroids: Therapies and Applications ISBN: 1632423820 ISBN-13(EAN): 9781632423825 Издательство: Неизвестно Цена: 122310.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Peplow Phil, Adams James, Young Tim Название: Cardiovascular and Metabolic Disease: Scientific Discoveries and New Therapies ISBN: 178262046X ISBN-13(EAN): 9781782620464 Издательство: Royal Society of Chemistry Рейтинг: Цена: 252030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides a complete picture of drug discovery for these inter-related conditions by bringing together the latest information and highlighting links between them.
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants--rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more.
This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries.
Автор: Akash, Navneet, B.S. Bhandari Название: Ethnomedicinal Plant Use and Practice in Traditional Medicine ISBN: 1799813207 ISBN-13(EAN): 9781799813200 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 264270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Traditional medicinal knowledge, especially the use of ethnomedicinal plants in developing countries, has been passed down for generations. Today, however, scientists are poised to combine traditional medicinal plants and modern drug discoveries to further develop essential products that have followed the leads of indigenous cures used for centuries.
Ethnomedicinal Plant Use and Practice in Traditional Medicine provides emerging research exploring the theoretical and practical aspects of indigenous knowledge and therapeutic potential within ethnobotany. Featuring coverage on a broad range of topics such as drug discovery, traditional knowledge, and herbal medicine, this book is ideally designed for doctors, healers, medical professionals, ethnobotanists, naturalists, academicians, researchers, and students interested in current research on the medical use and applications of natural-based resources.
Автор: Saroya, Amritpal Singh Название: Reverse pharmacology ISBN: 1138037079 ISBN-13(EAN): 9781138037076 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book serves as a reference guide for manufacturers and practitioners of herbal drugs. It is divided into two parts to differentiate between herbal drugs that are banned or restricted and herbal plants that are red listed. It is an invaluable resource to professionals in the herbal and pharmaceutical trades and in regulatory drug production.
Автор: Neha Mishra Название: Ethnopharmacological Investigation of Indian Spices ISBN: 1799825248 ISBN-13(EAN): 9781799825241 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 264270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Though their usage greatly diminished at the dawn of the scientific area, Indian spices were traditional parts of healthcare for thousands of years. However, over the last decade, largely due to the growth in popularity of complementary and alternative medicine, spices have regained attention due to their physiological and functional benefits. By applying modern research methods to traditional remedies, it is possible to discover what made these spices such effective ailment treatments.
Ethnopharmacological Investigation of Indian Spices is a collection of innovative research that analyzes the chemical properties and medical benefits of Indian spices in order to design new therapeutic drugs and for possible utility in the food industry. The book specifically examines the phytochemistry and biosynthetic pathway of active constituents of Indian spices. Highlighting a wide range of topics including pharmacology, antioxidant activity, and anti-cancer research, this book is ideally designed for pharmacologists, pharmacists, physicians, nutritionists, botanists, biotechnicians, biochemists, researchers, academicians, and students at the graduate and post-graduate levels interested in alternative healthcare.
Название: Therapies for Retinal Degeneration: Targeting Common Processes ISBN: 1782629491 ISBN-13(EAN): 9781782629498 Издательство: Royal Society of Chemistry Рейтинг: Цена: 209790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book addresses approaches to the treatment of retinal diseases, targeting common processes and components.
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