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Computer Techniques in Preclinical and Clinical Drug Development, Jackson, Robert C.


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Цена: 65320.00T
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Автор: Jackson, Robert C.
Название:  Computer Techniques in Preclinical and Clinical Drug Development
ISBN: 9780367401283
Издательство: Taylor&Francis
Классификация:
ISBN-10: 0367401282
Обложка/Формат: Paperback
Страницы: 256
Вес: 0.47 кг.
Дата издания: 20.12.2019
Язык: English
Размер: 234 x 156 x 14
Читательская аудитория: Tertiary education (us: college)
Основная тема: Computer Software-Pharmaceutical Science
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание: It is estimated that 80 to 90% of drugs under development never make it to the marketplace due to insufficient clinical activity, unacceptable toxicity, rapid appearance of drug resistance, or other factors that should be, at least partially, predictable from preclinical testing. This new text asks the question, How can we use computational methods to improve the success rate in drug development? Computer Techniques in Preclinical and Clinical Drug Development shows how modeling makes it possible to extract the maximum amount of information and predictive value from preclinical data. Computer modeling methods from the areas of pharmacokinetics, pharmacodynamics, cytokinetics, and inhibition kinetics of multi-enzyme pathways are all discussed in this unique reference source.

Modern Clinical Molecular Techniques

Автор: Hu Peter, Hegde Madhuri, Lennon Patrick Alan
Название: Modern Clinical Molecular Techniques
ISBN: 1461421691 ISBN-13(EAN): 9781461421696
Издательство: Springer
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Цена: 130430.00 T
Наличие на складе: Есть
Описание: This timely book covers the need to know clinical practices for all those involved in molecular laboratory science.

Transfusion Medicine and Patient Safety

Автор: Giustina De Silvestro, Arianna Veronesi, Maria Vicarioto
Название: Transfusion Medicine and Patient Safety
ISBN: 3110286971 ISBN-13(EAN): 9783110286977
Издательство: Walter de Gruyter
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Цена: 43330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Transfusional medicine is a young discipline, whereas the AB0 system was discovered only at the beginning of the last century, and that the neonatal haemolytic disease has been described in the middle of the 20th century.

Clinical Chemistry, Techniques, Principles, and Correlations, 6e

Автор: Bishop
Название: Clinical Chemistry, Techniques, Principles, and Correlations, 6e
ISBN: 078179045X ISBN-13(EAN): 9780781790451
Издательство: Lippincott Williams & Wilkins
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Цена: 50330.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for two-year Medical Laboratory Technician and four-year Medical Technology programs, this book focuses on what MLTs and MTs need to know. It intends to strike a balance between analytical principles and techniques and the correlation of laboratory results. It features a companion website with additional case studies, and a quiz bank.

Laboratory Diagnostic Pathways: Clinical Manual of Screening Methods and Stepwise Diagnosis

Автор: Walter Hofmann, Johannes Aufenanger, Georg Hoffmann
Название: Laboratory Diagnostic Pathways: Clinical Manual of Screening Methods and Stepwise Diagnosis
ISBN: 3110453673 ISBN-13(EAN): 9783110453676
Издательство: Walter de Gruyter
Цена: 111510.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The prognosis of a disease often depends on the timing of therapeutic invention, which in turn strongly relies on a reliable and quick diagnosis. Laboratory diagnostic pathways are algorithms that give structure to the diagnostic process, thereby minimizing the risk of mistreatment, shortening the hospital stay, and lowering the cost for treatment. This book offers 70 diagnostic algorithms that lead physicians and laboratory personnel through the diagnostic process in a step-by-step fashion. In Part One, general basics, infrastructure, and economic aspects are discussed and tipps for implementation are given. Part Two introduces screening methods for cases without a suspected diagnosis as well as specific pathways for stepwise diagnosis of the most common diseases, accompanied by information on pathophysiology, preanalytical measures, implementation, and interpretation of results.

Clinical Diagnostic Tests: How to Avoid Errors in Ordering Tests and Interpreting Results

Название: Clinical Diagnostic Tests: How to Avoid Errors in Ordering Tests and Interpreting Results
ISBN: 1620700832 ISBN-13(EAN): 9781620700839
Издательство: Mare Nostrum (Eurospan)
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Цена: 60990.00 T
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Описание: A convenient, quick-reference guide to common errors and pitfalls in test selection and result interpretation for practitioners and trainees in all areas of clinical medicine. Authored by recognized experts and educators in laboratory medicine, it provides timely, practical guidance about what to do and what not to do for practitioners ordering or interpreting clinical tests.

Molecular Diagnostics of Infectious Diseases

Автор: Harald H. Kessler
Название: Molecular Diagnostics of Infectious Diseases
ISBN: 3110327880 ISBN-13(EAN): 9783110327885
Издательство: Walter de Gruyter
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Цена: 117710.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The prevalence of infectious diseases is worldwide increasing. Therefore, detection methods for infectious pathogens change quickly. In the 3rd edition of Kessler´s Molecular Diagnostics of Infectious Diseases laboratory professionalists get valueable information about the current diagnostic methods, tipps and tricks in terms of sample processing, quality control, and interpretation of the results. For clinicians the book is a valuable aid for decision-making in ordering appropriate tests as well as in assuring the necessary quality of the sample material.

Pre-Examination Procedures in Laboratory Diagnostics: Preanalytical Aspects and their Impact on the Quality of Medical Laboratory Results

Автор: Walter G. Guder
Название: Pre-Examination Procedures in Laboratory Diagnostics: Preanalytical Aspects and their Impact on the Quality of Medical Laboratory Results
ISBN: 3110331659 ISBN-13(EAN): 9783110331653
Издательство: Walter de Gruyter
Цена: 123910.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Die Aussagekraft eines Laborbefundes hängt entscheidend von der Präanalytik ab, also von Prozessen, die vor der eigentlichen Messung der Proben im Labor ablaufen. Dieses Buch beschreibt alle präanalytischen Variablen - Indikation der Anforderung über Probengewinnung, Transport und Lagerung der Proben und Vorverarbeitung dieser für die Analyse - und definiert Qualitätskriterien der einzelnen Aspekte im Sinne einer evidenz-basierten Medizin.

Abdominal Wall Defects: Prevalence, Surgical Management Strategies & Clinical Care Outcomes

Автор: Jose J Diaz
Название: Abdominal Wall Defects: Prevalence, Surgical Management Strategies & Clinical Care Outcomes
ISBN: 1629486728 ISBN-13(EAN): 9781629486727
Издательство: Nova Science
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Цена: 205910.00 T
Наличие на складе: Невозможна поставка.
Описание: Since general surgeons first started performing laparotomies in the late 1880s, acquired hernias and abdominal wall defects have become a surgical disease of their own. Many surgeons have made it their lifes work to develop surgical techniques, design hernia meshes or utilise biologic tissue for repair of these abdominal wall defects. Hernias are defined as a defect in the normal architecture of the abdominal wall muscuolo-aponeuroic structure. They are subdivided into congenital or acquired hernias. The ventral or incisional hernia defects are rare due to the failure of normal healing of the incision after a laparotomy. The approach to the initial repair may be quite straightforward in the patient with a simple fascial defect who is otherwise healthy. As the size of the defect gets beyond 4 cm, or the patient has a significant co-morbid disease, other considerations must come into play. The component separation technique for abdominal wall reconstruction has brought many new young surgeons to focus their skills toward improving it. With the advances in critical care and peri-operative resuscitation together with knowledge of the abdominal compartment syndrome, surgeons are addressing very complicated ventral hernias. They commonly have significant loss of domain, tissue loss due to infection or tumour, or an entero-atmospheric intestinal fistula. The combined information in this text will help the surgeon identify the right surgical technique for the right patient. The focus of the text is the evaluation, prevalence, surgical techniques, and outcomes of patients undergoing complex ventral hernia repairs. The use of preoperative evaluation imaging is reviewed. The multiple etiologies of hernia and abdominal wall defects are mentioned. The surgical repairs utilising tissue repairs, both synthetic and biologic mesh are reviewed, and the component separation is discussed in detail. New endo/laparoscopic component separation techniques are also described. This text will become a must-have for every surgeon who takes care of patients with complex ventral hernias.

Histopathology of Preclinical Toxicity Studies,

Автор: Peter Greaves
Название: Histopathology of Preclinical Toxicity Studies,
ISBN: 0444538569 ISBN-13(EAN): 9780444538567
Издательство: Elsevier Science
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Цена: 167310.00 T
Наличие на складе: Поставка под заказ.
Описание: Describes the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. This reference is suitable for those involved in drug safety evaluation, including pathologists, toxicologists, and pharmacologists.

Effective Communication in Clinical Handover: From Research to Practice

Автор: Suzanne Eggins, Diana Slade, Fiona Geddes
Название: Effective Communication in Clinical Handover: From Research to Practice
ISBN: 3110378868 ISBN-13(EAN): 9783110378863
Издательство: Walter de Gruyter
Цена: 43330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Based on detailed multi-disciplinary analyses of more than 800 recorded handover interactions, audits of written handover documentation, interviews and survey responses, the contributing authors identify features of effective and ineffective clinical handovers in diverse hospital contexts. The authors then translate their descriptive findings into practical protocols, communication strategies and checklists that clinicians, managers and policy makers can apply to improve the safety and quality of clinical handovers. All the contributors are affiliated with the International Research Centre for Communication in Healthcare (IRCCH), an international multidisciplinary organisation of over 90 healthcare professionals from more than 17 countries committed to improving improving communication in healthcare systems around the world. 'The authors have created a new and tightly woven systems safety net that will, if implemented, significantly reduce the occurrence of errors resulting from cumulative communication failures.' -H. Esterbrook Longmaid III, MD, FACR, President of Medical Staff, Beth Israel Deaconess-Milton Hospital, Milton, MA USA 'Uncommonly valuable for the rigorous, original communication research it reports and for the careful translation of the research findings into practical strategies that actually improve clinical handovers in the real world of practice.' -Professor Suzanne Kurtz, Washington State University 'This clear, plain English book is an outstanding resource for the training of all involved in healthcare.' -Elizabeth Trickett, (Former) Director of Safety and Quality, ACT Health, Australia

Unimodal and Multimodal Biometric Data Indexing

Автор: Somnath Dey, Debasis Samanta
Название: Unimodal and Multimodal Biometric Data Indexing
ISBN: 1614517452 ISBN-13(EAN): 9781614517450
Издательство: Walter de Gruyter
Цена: 92910.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This work is on biometric data indexing for large-scale identification systems with a focus on different biometrics data indexing methods.  It provides state-of-the-art coverage including different biometric traits, together with the pros and cons for each.  Discussion of different multimodal fusion strategies are also included.


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