The basal ganglia are involved in complex brain functions, from voluntary movement control to learning and reward processing, and they are implicated in numerous neurological and psychiatric disorders. Information from the cerebral cortex and thalamus is conveyed to basal ganglia nuclei via glutamate release, while dopamine from the midbrain is released in close proximity to glutamate. At the heart of both function and dysfunction of basal ganglia circuits is the interaction of these two neurotransmitters, dopamine and glutamate.
Elucidating the relationship between their molecular and cellular effects and behavioural significance has been challenging, but in the past 5-10 years, improved labeling, imaging, recording, and genetic manipulation approaches have yielded new information on how dopamine and glutamate interact to generate the circuit activity underpinning basal ganglia function. Dopamine-Glutamate Interactions in the Basal Ganglia synthesizes this recent researchfrom the level of receptor molecules all the way to complex behaviours and disease.
Current insights from research on individual neurons and synapses, detailed circuit analysis, and learning and action functions of the basal ganglia are presented against a historical perspective. The book also discusses compromised dopamine-glutamate interaction in disorders of basal ganglia function, including Parkinson's disease, Huntington's disease, and drug addiction.
Автор: Kim Neve Название: The Dopamine Receptors ISBN: 1617796565 ISBN-13(EAN): 9781617796562 Издательство: Springer Рейтинг: Цена: 287890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This revised book serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. There are new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization.
Автор: Mario Tiberi Название: Dopamine Receptor Technologies ISBN: 149394889X ISBN-13(EAN): 9781493948895 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: To foster a better understanding of dopamine receptor functionality, this detailed volume creates an interface between updated classical methods and new emerging technologies heretofore not available to new or seasoned researchers.
Автор: Endo Kudo Название: Dopamine: Functions, Regulation & Health Effects ISBN: 161942147X ISBN-13(EAN): 9781619421479 Издательство: Nova Science Рейтинг: Цена: 205910.00 T Наличие на складе: Невозможна поставка. Описание: The critical introduction to this Broadview Edition gives particular emphasis to Wells`s hostility towards religion as well as his thorough knowledge of the Darwinian thought of his time. Appendices provide passages from Darwin and Huxley related to Wells`s early writing; in addition, excerpts from other writers illustrate late-nineteenth-century anxieties about social degeneration.
Автор: Iversen, Leslie; Iversen, Susan; Dunnett, Stephen; Название: Dopamine Handbook (Hardback) ISBN: 0195373030 ISBN-13(EAN): 9780195373035 Издательство: Oxford Academ Рейтинг: Цена: 163680.00 T Наличие на складе: Поставка под заказ. Описание: The discovery of dopamine in 1957 was one of the seminal events in the development of modern neuroscience, and has been extremely important for the development of modern therapies of neurological and psychiatric disorders. The Dopamine Handbook is the first single-volume publication to capture current progress and excitement in this dynamic research field.
Автор: Kim A. Neve (Ed.) Название: The Dopamine Receptors ISBN: 1603273328 ISBN-13(EAN): 9781603273329 Издательство: Springer Рейтинг: Цена: 287890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This revised book serves as a reference work on dopamine receptors while also highlighting the areas of research that are most active today. There are new chapters on dopamine receptor-interacting proteins and on dopamine receptor oligomerization.
Автор: Glenda Halliday, PhD... Название: Non-dopamine Lesions in Parkinson`s Disease ISBN: 0195371089 ISBN-13(EAN): 9780195371086 Издательство: Oxford Academ Рейтинг: Цена: 145200.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Parkinson's disease becomes apparent only after substantial loss (>60%) of the dopamine neurons in the substantia nigra. By this time there has already been widespread neural inclusion formation in the peripheral and central nervous system of patients with the disease, although this has only been recognized more recently. Degeneration in these widespread regions of the peripheral and central nervous system is now known to impact on disease symptoms, progression and treatment over time. This book aims to provide a comprehensive review of these non-dopamine lesions in Parkinson's disease by assessing our current knowledge of their presence and pathophysiology, how they relate to different symptoms and, where relevant, discuss how they may be potentially treated. The book addresses most of the known symptoms that occur in patients with Parkinson's disease. In addition to the classic motor triad, motor speech, eye movements, olfactory dysfunction, autonomic dysfunction, pain and sensory abnormalities, sleep disturbances, depression and apathy, dopamine dysregulation syndromes, hallucinations and psychoses, cognitive impairment and dementia, and systemic manifestations are all reviewed. Early selective cell loss in non-dopaminergic regions is highlighted (the glutamate projection neurons of the presupplementary motor cortex and caudal intralaminar thalamus) in addition to the widespread inclusion formation in many regions outside the basal ganglia that characterize the disease. Overall this book provides a comprehensive analysis of the lesions associated with the most common symptoms found in patients with Parkinson's disease.
Автор: Jeroen Pasterkamp; Marten P. Smidt; J. Peter H. Bu Название: Development and Engineering of Dopamine Neurons ISBN: 1441903216 ISBN-13(EAN): 9781441903211 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections.
Автор: Kabbani Название: Dopamine ISBN: 1627032509 ISBN-13(EAN): 9781627032506 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Methods in Molecular Biology(TM) book offers protocols for bioluminescence and fluorescence imaging, receptor immunoprecipitation and proteomic analysis, creation of a mouse model of Parkinson`s disease, real time measurement of dopamine in the brain and more.
Автор: Sidhu Anita Название: Dopamine Receptors And Transporters: Pharmacology, Structure And Function: V. 56 ISBN: 0824708547 ISBN-13(EAN): 9780824708542 Издательство: Taylor&Francis Рейтинг: Цена: 209270.00 T Наличие на складе: Невозможна поставка. Описание: "Details the function, characterization, and physiology of various dopamine receptor/transporter systems and explores their role in etiology, diagnosis, and disease management."
Автор: Nadine Kabbani Название: Dopamine ISBN: 1493963333 ISBN-13(EAN): 9781493963331 Издательство: Springer Рейтинг: Цена: 135090.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Methods in Molecular Biology (TM) book offers protocols for bioluminescence and fluorescence imaging, receptor immunoprecipitation and proteomic analysis, creation of a mouse model of Parkinson`s disease, real time measurement of dopamine in the brain and more.
Автор: Monti Название: Dopamine and Sleep ISBN: 3319464353 ISBN-13(EAN): 9783319464350 Издательство: Springer Рейтинг: Цена: 158380.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
