Автор: Cornel Mulhardt Название: Molecular Biology and Genomics, ISBN: 0120885468 ISBN-13(EAN): 9780120885466 Издательство: Elsevier Science Рейтинг: Цена: 45150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Never before has it been so critical for lab workers to possess the proper tools and methodologies necessary to determine the structure, function, and expression of the corresponding proteins encoded in the genome. Mulhardt's Molecular Biology and Genomics helps aid in this daunting task by providing the reader with tips and tricks for more successful lab experiments. This strategic lab guide explores the current methodological variety of molecular biology and genomics in a simple manner, addressing the assets and drawbacks as well as critical points. It also provides short and precise summaries of routine procedures as well as listings of the advantages and disadvantages of alternative methods.
Автор: Strachan Название: Human Molecular Genetics ISBN: 0815345895 ISBN-13(EAN): 9780815345893 Издательство: Taylor&Francis Рейтинг: Цена: 80630.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Human Molecular Genetics has been carefully crafted over successive editions to provide an authoritative introduction to the molecular aspects of human genetics, genomics and cell biology.
Maintaining the features that have made previous editions so popular, this fifth edition has been completely updated in line with the latest developments in the field. Older technologies such as cloning and hybridization have been merged and summarized, coverage of newer DNA sequencing technologies has been expanded, and powerful new gene editing and single-cell genomics technologies have been added. The coverage of GWAS, functional genomics, stem cells, and disease modeling has been expanded. Greater focus is given to inheritance and variation in the context of populations and on the role of epigenetics in gene regulation.
Key features:
Fully integrated approach to the molecular aspects of human genetics, genomics, and cell biology
Accessible text is supported and enhanced throughout by superb artwork illustrating the key concepts and mechanisms
Summary boxes at the end of each chapter provide clear learning points
Annotated further reading helps readers navigate the wealth of additional information in this complex subject and provides direction for further study
Reorganized into five sections for improved access to related topics
Also new to this edition - brand new chapter on evolution and anthropology from the authors of the highly acclaimed Human Evolutionary Genetics
A proven and popular textbook for upper-level undergraduates and graduate students, the new edition of Human Molecular Genetics remains the 'go-to' book for those studying human molecular genetics or genomics courses around the world.
Автор: Jonathan Pevsner Название: Bioinformatics and Functional Genomics ISBN: 1118581784 ISBN-13(EAN): 9781118581780 Издательство: Wiley Рейтинг: Цена: 118220.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The bestselling introduction to bioinformatics and genomics now in its third edition Widely received in its previous editions, Bioinformatics and Functional Genomics offers the most broad-based introduction to this explosive new discipline.
At a ceremony announcing the completion of the first draft of the human genome in 2000, President Bill Clinton declared, "I believe one of the great truths to emerge from this triumphant expedition inside the human genome is that in genetic terms, all human beings, regardless of race, are more than 99.9 percent the same." Yet despite this declaration of unity, biomedical research has focused increasingly on mapping that.1 percent of difference, particularly as it relates to race.
This trend is exemplified by the drug BiDil. Approved by the FDA in 2005 as the first drug with a race-specific indication on its label, BiDil was originally touted as a pathbreaking therapy to treat heart failure in black patients and help underserved populations. Upon closer examination, however, Jonathan Kahn reveals a far more complex story. At the most basic level, BiDil became racial through legal maneuvering and commercial pressure as much as through medical understandings of how the drug worked.
Using BiDil as a central case study, Kahn broadly examines the legal and commercial imperatives driving the expanding role of race in biomedicine, even as scientific advances in genomics could render the issue irrelevant. He surveys the distinct politics informing the use of race in medicine and the very real health disparities caused by racism and social injustice that are now being cast as a mere function of genetic difference. Calling for a more reasoned approach to using race in biomedical research and practice, Kahn asks readers to recognize that, just as genetics is a complex field requiring sensitivity and expertise, so too is race, particularly in the field of biomedicine.
Автор: Henrich, Vincent Название: Henrich-Managing Patient Health in the Genomic Era ISBN: 0128160152 ISBN-13(EAN): 9780128160152 Издательство: Elsevier Science Рейтинг: Цена: 119030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
In recent years genomic medicine has grown from a new medical science to an implementable set of clinical methods and technologies whose concrete applications are revolutionizing the health sector. However, most primary care and family health practitioners still have limited experience employing genetic and genomic approaches effectively in their daily practice.
In Managing Patient Health in the Genomic Era: Family Health History and Chronic Disease Risk, Drs. Vincent Henrich, Lori Orlando, and Brian Shirts discuss the practical considerations surrounding the use of genomic and genetic tests to manage patient health, provide adult disease risk assessment, improve diagnosis, and support effective interventions and treatment. In ten chapters, evidence-based information and case studies are described and examine the central place of family health history (FHH) in genomic medicine, tools and strategies for compiling and analysing family health history, how to identify existing and novel genetic markers, how to identify lineage specific (or rare) variants within families, and how to find effective interventions based on genetic testing results and FHH. Factors which influence clinical practice, including gene-environment interactions, FHH social networking, direct to consumer (DTC) genetic testing and data sharing, algorithms for analyzing genetic data, and patient counseling are discussed from the standpoint of clinical practice.
Here frontline healthcare providers will discover succinct commentary and key examples to assist with their local needs. Relevant principles of genetic biology and inheritance are explored and guidance on available support networks and online resources is also provided.
Presents a practical, accessible resource for primary care providers, allied health professionals, pharmacologists, public health professionals, students and clinical researchers
Addresses genetic and genomic approaches in managing patient health, conducting and analyzing family health histories, and assessing adult disease risk
Features an expert author team with direct experience integrating genetics and genomics in primary care and family medicine settings
Examines the attributes and limitations of family health history, genetic testing, and genomic testing in clinical practice
Includes detailed explanations following practice-based examples
Автор: Jos? Mar?a Frade; Fred H. Gage Название: Genomic Mosaicism in Neurons and Other Cell Types ISBN: 1493984403 ISBN-13(EAN): 9781493984404 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Поставка под заказ.
Автор: Smith, Moyra (division Of Genetic And Genomic Medicine, Department Of Pediatrics, University Of California Irvine, Irvine, Ca, United States) Название: Mechanisms and genetics of neurodevelopmental cognitive disorders ISBN: 0128219130 ISBN-13(EAN): 9780128219133 Издательство: Elsevier Science Рейтинг: Цена: 132500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mechanisms and Genetics of Neurodevelopmental Cognitive Disorders connects neurodevelopment with genetics and behavior to better understand the underlying factors leading to cognitive neurodevelopmental disorders. This book focuses on mechanisms of disease and follows the development of specific brain regions, functions, and gene expression to causes and processes in autism, attention deficit disorder, and learning disabilities. Topics include brain mapping, brain plasticity, epigenetics, neuroimmunology, and many other factors that influence the development of these diseases.
This book will promote understanding of recent investigations and developments related to brain development from fetal life onward with specific relevance to neurodevelopmental cognitive disorders and conditions. This is an essential reference for anyone who is looking to learn more about different aspects of neurodevelopment and emerging concepts in psychiatric disorders.
Автор: Isabelle Peter Название: Genomic Control Process ISBN: 0124047297 ISBN-13(EAN): 9780124047297 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Поставка под заказ. Описание: Explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. This book covers a vast area of biological research to produce a genome oriented regulatory bioscience of animal life.
Автор: Surinder Singh Papiha; Ranjan Deka; Ranajit Chakra Название: Genomic Diversity ISBN: 1461369142 ISBN-13(EAN): 9781461369141 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the Symposium on Molecular Anthropology in the 21st Century, held during the 14th International Congress of the Association of Anthropological and Ethnological Sciences, 26 July to 1 August, 1998, in Williamsburg, Virginia, USA
Автор: Kishore R. Sakharkar, Meena K. Sakharkar, Ramesh Chandra Название: Post-genomic Approaches in Cancer and Nano Medicine ISBN: 8793102860 ISBN-13(EAN): 9788793102866 Издательство: Taylor&Francis Рейтинг: Цена: 88800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Understanding the molecular mechanisms of cancer is the key for transforming cancer medicine. Seen in several cancers is a substantial proportion of human genes showing alternative splicing and mis-regulation of Pre-mRNA splicing.
Post-genomic Approaches in Cancer and Nano Medicine further investigates these matters. The first few chapters provide an update on the role of genomics in understanding alternative splicing and targets in cancer pathogenesis. Advances and prospects in applications of nanotechnology for cancer prevention, detection, and treatment are a promising field of research. The subsequent chapters provide insights on how nanotechnology-based therapeutics are moving toward revolutionizing cancer and infectious disease treatment by minimizing toxicity and facilitating targeted delivery of drugs.
Technical topics discussed in the book include: - Alternative splicing and cancer - Cancer imaging - Nanomaterials in infectious diseases - Nanomedicine in oxidative stress and cancer - Nanoparticle based drug delivery systems
Автор: Hodgman Charlie, Lu Chungui, Kirk Sandra Название: Advanced Textbook On Genomic And Proteomic Sciences, An ISBN: 1848167865 ISBN-13(EAN): 9781848167865 Издательство: World Scientific Publishing Цена: 86590.00 T Наличие на складе: Поставка под заказ. Описание: This book aims to equip readers with modern molecular biology concepts and techniques including genomics, transcriptomics, proteomics, bioinformatics, metabolomics and systems biology. It will provide students, researchers and lecturers with a core understanding of a newly emerging field that is of relevance to the industrial/academic arenas. As a result, they can create insightful and inventive solutions to common problems, and describe and explore the current field of post-genomic ('omics') technologies.
Автор: Joseph P Damon Название: Whole Genome Sequencing: Privacy & Security in an Era of Genomic Advancements ISBN: 1631171577 ISBN-13(EAN): 9781631171574 Издательство: Nova Science Рейтинг: Цена: 168950.00 T Наличие на складе: Невозможна поставка. Описание: Over the course of less than a decade, whole genome sequencing has progressed from being one of our nations boldest scientific aspirations to becoming a readily available technique for determining the complete sequence of an individuals deoxyribonucleic acid (DNA) -- that persons unique genetic blueprint. This book focuses on the privacy and progress in whole genome sequencing; and provides a scientific background for policymakers in genetic testing.
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