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Animal Models of Cognitive Impairment, 


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Название:  Animal Models of Cognitive Impairment
ISBN: 9780367390679
Издательство: Taylor&Francis
Классификация:


ISBN-10: 0367390671
Обложка/Формат: Paperback
Страницы: 396
Вес: 1.61 кг.
Дата издания: 27.09.2019
Язык: English
Размер: 235 x 159
Читательская аудитория: Tertiary education (us: college)
Основная тема: Neurology
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

The costs associated with a drugs clinical trials are so significant that it has become necessary to validate both its safety and efficacy in animal models prior to the continued study of the drug in humans.

Featuring contributions from distinguished researchers in the field of cognitive therapy research, Animal Models of Cognitive Impairment examines some of the most popular and successful animal archetypes used in the context of drug discovery. It provides integrated coverage of the latest research concerning neuronal systems relevant to cognitive function and dysfunction, assimilating reviews of this research within the context of each chapter. This approach is unique in that it brings together molecular and neurochemical methodologies, behavioral applications in translational models, and clinical applications.

The book comprehensively discusses a wide variety of animal models of cognitive impairment, including genetic, lesion, pharmacological, and aging related impairments. It also explores the significance of this research in regards to the treatment of various addictions and disorders such as stroke, autism, Alzheimers, schizophrenia, and ADHD.

Edited by two renowned authorities in the field, Animal Models of Cognitive Impairment is a timely book that provides integrated coverage of cutting-edge research that concerns neuronal systems relevant to cognitive function and dysfunction.



Acute Brain Impairment: Scientific Discoveries and Translational Research

Автор: Peplow
Название: Acute Brain Impairment: Scientific Discoveries and Translational Research
ISBN: 1782629505 ISBN-13(EAN): 9781782629504
Издательство: Royal Society of Chemistry
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Цена: 209790.00 T
Наличие на складе: Нет в наличии.
Описание: A book useful to postgraduate students and researchers in medicinal chemistry and pharmacology, as well as specialists in the acute brain injury field.

Cognitive Impairment & Survival After a Natural Disaster: Lessons Learned from Life Experiences in the Great East Japan Earthquake of 2011

Автор: Kenichi Meguro
Название: Cognitive Impairment & Survival After a Natural Disaster: Lessons Learned from Life Experiences in the Great East Japan Earthquake of 2011
ISBN: 1536108243 ISBN-13(EAN): 9781536108248
Издательство: Nova Science
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Цена: 122490.00 T
Наличие на складе: Невозможна поставка.
Описание: Behavioural neurology is a subspecialty of neurology that investigates the neurological basis of human behaviour and cognitive function. Recently, dementing diseases have become so common that their behavioural abnormalities are now being investigated with reference to brain damage. During a big disaster, which can critically affect the human population, people should utilise their brains fully in order to survive, that is, to understand the situation around them, to make a proper judgement, and to decide their behaviours; these are associated with brain functions. However, disaster medicine is focused mainly on the environment, with the underlying assumption that brain function is always normal, and thus judgement and behaviour remain normal. By contrast, dementia medicine does not always consider dementia in determining peoples behaviours during the disaster. The author believes that approaches to brain-based disaster medicine and disaster-associated dementia medicine have not been fully integrated nor even investigated. Herein, the author focuses on reconstruction support after the Great East Japan earthquake in 2011, from an academic perspective, with particular respect to behavioural neurology based on his own experiences.

Sleep, Epilepsies, and Cognitive Impairment

Автор: Halasz, Peter
Название: Sleep, Epilepsies, and Cognitive Impairment
ISBN: 0128125799 ISBN-13(EAN): 9780128125793
Издательство: Elsevier Science
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Цена: 85330.00 T
Наличие на складе: Поставка под заказ.
Описание:

Translational research connects science and clinical medicine from "the bench to the bedside." In Sleep, Epilepsies and Cognitive Impairment, the authors look back from the bedside to the brain function underlying clinical symptoms and reveal mechanisms explored by contemporary neuroimaging and signal analysis in the overlapping fields of sleep and epilepsy. This book will help the reader to see epilepsy from a new viewpoint.

The common pathophysiology binding together the diverse manifestations of epilepsies is the exaggeration of plastic functions of the brain involving the hippocampus, the non-specific thalamocortical system and the perisylvian cognitive network. Epileptic derailment seems to be the price for the latest achievements of the mammal and human brain; namely the highly developed ability to change and learn. The contemporary results of sleep research provide new viewpoints to explain why sleep and epilepsy are bedfellows. Converging evidence supports the concept that one of the most important biological roles of NREM sleep is the renewal of synaptic balance ensuring learning ability from one day to the next and consolidation of new memories. Epilepsy and NREM sleep use overlapping structures and functions, therefore epilepsy beginning in early childhood may interfere with sleep plastic functions. NREM sleep, which affects original learning and memory, may become the hidden source of chronic cognitive impairment when epilepsy occurs during sleep and blocks the plastic processes.

Sleep, Epilepsies and Cognitive Impairment abandons the academic classification of epilepsy by following the system epilepsy concept, binding major epilepsies with structures and functions of physiological brain systems. It tries to show within this system the close interrelationship between sleep, epilepsy and cognition.

Neuroscientists, clinical epileptologists and neurologists interested in brain processes underlying brain plasticity, sleep and epilepsy will find this book thought provoking. It offers good "brain-gymnastics" for reconsidering the ideas on epilepsy.

  • It provides contemporary knowledge about the neurophysiological and functional anatomical background of major epilepsies
  • Treats major epilepsies as system epilepsies of brain networks
  • Reveals the interrelationship of sleep, epilepsy and cognitive impairment showing how epileptic manifestations became facilitated in NREM sleep and interferes with sleep plastic functions

Coping with Mild Cognitive Impairment (MCI)

Автор: Jordan, Mary
Название: Coping with Mild Cognitive Impairment (MCI)
ISBN: 1787750906 ISBN-13(EAN): 9781787750906
Издательство: Jessica Kingsley
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Цена: 0.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Practical self-help strategies for older individuals and their families to help slow the onset of Mild Cognitive Impairment. Includes activities, health and lifestyle changes, memory aids, therapies and technological aids. Also suitable for those with early stage dementia wishing to prevent the condition worsening.

Neuropsychiatric Symptoms of Cognitive Impairment and Dementia

Автор: Ana Verdelho; Manuel Gon?alves-Pereira
Название: Neuropsychiatric Symptoms of Cognitive Impairment and Dementia
ISBN: 3319818279 ISBN-13(EAN): 9783319818276
Издательство: Springer
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Цена: 111790.00 T
Наличие на складе: Невозможна поставка.
Описание: This book is an up-to-date, comprehensive review of the neuropsychiatry of different types of cognitive impairment by active authorities in the field. A critical appraisal of the methodological aspects and limitations of the current research on the neuropsychiatry of cognitive impairment and dementia is included.

Vascular Cognitive Impairment

Автор: Erkinjuntti
Название: Vascular Cognitive Impairment
ISBN: 1853179396 ISBN-13(EAN): 9781853179396
Издательство: Informa
Цена: 190630.00 T
Наличие на складе: Нет в наличии.
Описание: Accurate assessment of vascular cognitive impairment and vascular disease are important challenges for the practicing clinician, this book helps to address those challenges thus hopefully benefiting patients with early detection and therapy.

Sensorimotor Impairment in the Elderly

Автор: George E. Stelmach; Volker H?mberg
Название: Sensorimotor Impairment in the Elderly
ISBN: 940104872X ISBN-13(EAN): 9789401048729
Издательство: Springer
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Цена: 279500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Proceedings of the NATO Advanced Research Workshop, Bad Windsheim, Germany, September 11-13, 1992


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